thyrotoxic ophthalmopathy

バセドウ病眼症

WordNet

1. of or relating to or affected by hyperthyroidism

UpToDate Contents

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• 1. 甲状腺機能亢進症およびバセドウ病の神経学的症状 neurologic manifestations of hyperthyroidism and graves disease
• 2. バセドウ眼症（グレーブス眼症：眼窩疾患）の病因および臨床的特徴 pathogenesis and clinical features of graves ophthalmopathy orbitopathy
• 3. 小児や青年の甲状腺機能亢進症の臨床症状および診断 clinical manifestations and diagnosis of hyperthyroidism in children and adolescents
• 4. 甲状腺中毒性周期性四肢麻痺 thyrotoxic periodic paralysis
• 5. バセドウ眼症（グレーブス眼窩疾患：眼症）の治療 treatment of graves orbitopathy ophthalmopathy

English Journal

• Steroid-induced thyrotoxic periodic paralysis during Graves' ophthalmopathy treatment.

• Sayiner ZA1, Eraydın A1, Akarsu E1.
• Postgraduate medical journal.Postgrad Med J.2016 Aug 26. pii: postgradmedj-2016-134292. doi: 10.1136/postgradmedj-2016-134292. [Epub ahead of print]
• PMID 27566533

• Heart Failure in Thyrotoxic Cardiomopathy: Extracorporeal Membrane Oxygenation Treatment for Graves' Disease.

• Allencherril J1, Birnbaum I1.
• The journal of extra-corporeal technology.J Extra Corpor Technol.2015 Dec;47(4):231-2.
• Thyrotoxicosis-induced cardiomyopathy and consequent heart failure is one of the most grave complications of uncontrolled hyperthyroidism. In such patients, early recognition of thyrotoxicosis, and directed antithyroid therapy can lead to rapid normalization of left ventricular function. Herein, we
• PMID 26834286

• Moyamoya disease concurrent with Graves' disease treated by direct bypass: clinical features and treatment strategies.

• Ryu B1, Kawamata T, Yamaguchi K, Kawashima A, Ono M, Okada Y.
• Acta neurochirurgica.Acta Neurochir (Wien).2015 Jul;157(7):1095-102. doi: 10.1007/s00701-015-2422-8. Epub 2015 May 1.
• BACKGROUND: Moyamoya disease (MMD) concurrent with Graves' disease (GD) is rare. There is no guideline about optimizing thyroid hormones and the appropriate timing of surgical treatment for MMD with GD.METHODS: We encountered eight patients with MMD and GD presenting with cerebral ischemia who were
• PMID 25929211

Japanese Journal

• Ｅｕｔｈｙｒｏｉｄ　ｏｐｈｔｈａｌｍｏｐａｔｈｙの臨床免疫学的特徴

• 日本臨床免疫学会会誌 13(2), 127-135, 1990
• NAID 130000851260

Related Links

• Imaging in Thyroid Ophthalmopathy: Overview, Radiography ...

Thyroid ophthalmopathy is currently is recognized as the most common cause of proptosis (protrusion of the globe) in adults (see the first image below). Other clinical features include upper and/or lower eyelid retraction ...

• Graves’ Ophthalmopathy - National Center for Biotechnology ...

ANATOMICAL AND HISTOLOGIC FINDINGS Many clinical signs and symptoms of Graves’ ophthalmopathy arise from soft-tissue enlargement in the orbit, leading to increased pressure within the bony cavity. 20,21 Most ...

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★リンクテーブル★

リンク元	「バセドウ病眼症」
関連記事	「ophthalmopathy」

「バセドウ病眼症」

　　[★]

英

Basedow ophthalmopathy

同

グレーブズ病眼症 Graves眼症 Graves ophthalmopathy Graves' ophthalmopathy, 甲状腺機能亢進性眼病変 thyrotoxic ophthalmopathy, 甲状腺眼症状 甲状腺眼症 dysthyroid ophthalmopathy thyroid associated ophthalmopathy thyroid-associated ophthalmopathy TAO、浸潤性眼症 infiltrative ophthalmopathy

関

グレーブス病

概念

• 眼球突出、眼球運動障害、眼瞼浮腫、結膜充血、視神経障害などの眼病変がバセドウ病患者にみられることをいう。

病態生理

• 眼窩内組織(外眼筋、球後結合組織)にTSH受容体を介する自己免疫機序を開始、外眼筋肥厚、脂肪組織増生、涙腺肥大を生じ、結果として眼窩内圧が上昇する。これにより眼球突出をきたす。

症状

SOP. 184

眼窩脂肪織・外眼筋の肥大　→　眼窩内容増大

• 眼瞼腫脹　眼瞼浮腫？
• 眼瞼後退

徴候

• ステルワーグ徴候 Stellwag sign：瞬目の減少
• グレーフェ徴候 Graefe sign lid lag：下方視に際して上眼瞼が下降しないため強膜上部が露出　←　上眼瞼筋の緊張
• ダルリンプル徴候 Dalrymple sign：眼瞼開大。交感神経優位となりMuller筋が異常に収縮することによる
• メビウス徴候 Mobius sign：輻輳不全

参考

• 1. [charged] Pathogenesis and clinical features of Graves' ophthalmopathy (orbitopathy) - uptodate [1]
• 2. [charged] Treatment of Graves' orbitopathy (ophthalmopathy) - uptodate [2]

「ophthalmopathy」

　　[★]

• n.

• 眼疾患、眼障害、眼症

関

eye disease、eye disorder