WordNet

street name for lysergic acid diethylamide (同)back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen
any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt
having the characteristics of an acid; "an acid reaction"

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Synthesis and evaluation of 5'-modified thymidines and 5-hydroxymethyl-2'-deoxyuridines as Mycobacterium tuberculosis thymidylate kinase inhibitors.

Toti KS, Verbeke F, Risseeuw MD, Frecer V, Munier-Lehmann H, Van Calenbergh S.SourceLaboratory for Medicinal Chemistry, Faculty of Pharmaceutical Sciences (FFW), Ghent University, Harelbekestraat 72, 9000 Ghent, Belgium.
Bioorganic & medicinal chemistry.Bioorg Med Chem.2013 Jan 1;21(1):257-68. doi: 10.1016/j.bmc.2012.10.018. Epub 2012 Nov 5.
We report the synthesis of 5'-modified thymidines (16, 18, 21, 23) and 5,5'-bis-substituted 2'-deoxyuridine analogues (30, 47) as inhibitors of thymidine monophosphate kinase of Mycobacterium tuberculosis (TMPKmt). These analogues were evaluated for their capacity to inhibit TMPKmt and solely two 5'
PMID 23199481

Structural and chemical basis for enhanced affinity to a series of mycobacterial thymidine monophosphate kinase inhibitors: fragment-based QSAR and QM/MM docking studies.

Bueno RV, Toledo NR, Neves BJ, Braga RC, Andrade CH.SourceLaboratório de Planejamento de Fármacos e Estudos de Metabolismo por Modelagem Molecular (LabMol), Faculdade de Farmácia, Universidade Federal de Goiás, 74605-220, Goiania, GO, Brazil.
Journal of molecular modeling.J Mol Model.2013 Jan;19(1):179-92. doi: 10.1007/s00894-012-1527-8. Epub 2012 Jul 31.
Tuberculosis (TB) still remains one of the most deadly infectious diseases. Mycobacterium tuberculosis thymidine monophosphate kinase (TMPKmt) has emerged as an attractive molecular target for the design of a novel class of anti-TB agents since blocking it will affect the pathways involved in DNA re
PMID 22846924

A highly sensitive capillary electrophoresis method using p-nitrophenyl 5'-thymidine monophosphate as a substrate for the monitoring of nucleotide pyrophosphatase/phosphodiesterase activities.

Lee SY, Lévesque SA, Sévigny J, Müller CE.SourcePharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.J Chromatogr B Analyt Technol Biomed Life Sci.2012 Dec 12;911:162-9. doi: 10.1016/j.jchromb.2012.10.044. Epub 2012 Nov 7.
A highly sensitive capillary electrophoresis method has been developed to monitor the activity of nucleotide pyrophosphatases/phosphodiesterases (NPPs) and screen for NPP inhibitors. In this method, p-nitrophenyl 5'-thymidine monophosphate (p-Nph-5'-TMP) was used as an artificial substrate, and sepa
PMID 23217320

Crystal structure disposition of thymidylic acid tetramer in complex with ribonuclease A

DETERMINATION OF DEOXYMONONUCLEOTIDES AND DEOXYNUCLEOSIDES AS A TOOL FOR TOXICOLOGICAL EXAMINATION : A TRIAL FOR CONVERSION OF ABSORBANCE UNIT INTO MOLAR AMOUNT IN DEOXYDINUCLEOTIDE