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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/09/09 18:06:08」(JST)

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  • The Role of β-Catenin in Bcr/Abl Negative Myeloproliferative Neoplasms: An Immunohistochemical Study.
  • Geduk A1, Atesoglu EB2, Tarkun P2, Mehtap O2, Hacihanefioglu A2, Demirsoy ET2, Baydemir C3.
  • Clinical lymphoma, myeloma & leukemia.Clin Lymphoma Myeloma Leuk.2015 Dec;15(12):785-9. doi: 10.1016/j.clml.2015.08.084. Epub 2015 Sep 3.
  • INTRODUCTION: β-Catenin is a multifunctional protein that acts as a central effector molecule in the Wnt signaling pathway. Aberrant activation of the Wnt/β-catenin signaling pathway causes various diseases including cancer. In this study we evaluated β-catenin expression in bcr/abl-negative myel
  • PMID 26422250
  • Immature platelet fraction measurement is influenced by platelet size and is a useful parameter for discrimination of macrothrombocytopenia.
  • Miyazaki K, Koike Y, Kunishima S, Ishii R, Danbara M, Horie R, Yatomi Y, Higashihara M.
  • Hematology (Amsterdam, Netherlands).Hematology.2015 Dec;20(10):587-92. doi: 10.1179/1607845415Y.0000000021. Epub 2015 Jun 2.
  • Background Reticulated platelets (RPs) as measured using flow cytometry are useful parameters of thrombopoiesis; however, difficulties remain with standardization between laboratories. On the other hand, immature platelet fraction (IPF) measurement, as determined using an automated hematology analyz
  • PMID 26035037
  • Analyses of Genetic and Clinical Parameters for Screening Patients With Inherited Thrombocytopenia with Small or Normal-Sized Platelets.
  • Ouchi-Uchiyama M1,2, Sasahara Y1, Kikuchi A1, Goi K3, Nakane T3, Ikeno M4, Noguchi Y5, Uike N6, Miyajima Y7, Matsubara K8, Koh K9, Sugita K3, Imaizumi M2, Kure S1.
  • Pediatric blood & cancer.Pediatr Blood Cancer.2015 Dec;62(12):2082-8. doi: 10.1002/pbc.25668. Epub 2015 Jul 14.
  • BACKGROUND: Childhood thrombocytopenias include immune thrombocytopenic purpura (ITP) and inherited thrombocytopenia; the former is caused by autoantibodies to platelets, whereas the latter can be distinguished by platelet size and underlying genetic mutations. Due to limited methods for the definit
  • PMID 26175287


  • Pluripotent stem cells reveal the developmental biology of human megakaryocytes and provide a source of platelets for clinical application.
  • Takayama Naoya,Eto Koji
  • Cellular and molecular life sciences : CMLS 69(20), 3419-3428, 2012-10
  • … Megakaryocytes (MKs) and platelets can be created from human ESCs and iPSCs in vitro and represent a potential source of blood cells for transfusion and a promising tool for studying the human thrombopoiesis. … Combining this co-culture system with a drug-inducible gene expression system enabled us to clarify the novel role played by c-MYC during human thrombopoiesis. …
  • NAID 120004920418
  • Gene substitutions in relation to megakaryopoiesis and thrombopoiesis
  • Transcriptional regulation of megakaryopoiesis and thrombopoiesis
  • 藤田 理恵,本橋 ほづみ,山本 雅之
  • 日本血栓止血学会誌 23(6), 539-543, 2012
  • NAID 130003367323


thrombopoiesis throm·bo·poi·e·sis (thrŏm'bō-poi-ē'sĭs) n. The process of blood clot formation. The formation of blood platelets.
thrombopoiesis /throm·bo·poi·e·sis/ (-poi-e?sis) 1. thrombogenesis. 2. thrombocytopoiesis.thrombopoiet?ic throm·bo·poi·e·sis (thrŏm′bō-poi-ē′sĭs) n. 1. The process of blood clot formation. 2. The formation of blood platelets.


bigThrombopoiesis_01.jpg mechanisms that control thrombopoiesisThrombopoiesis refers to the process of Illustration of blood cell lineage, a Thrombopoiesis (Megakaryocytopoiesis)Thrombopoiesis (Megakaryocytopoiesis)













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