thioridazine

出典: meddic

チオリダジン

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「a tranquilizer (trade name Mellaril) used to treat schizophrenia and other psychotic disorders」
Mellaril

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/06/14 08:39:57」(JST)

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英文文献

  • Effects of proarrhythmic drugs on relaxation time and beating pattern in rat engineered heart tissue.
  • Eder A1, Hansen A, Uebeler J, Schulze T, Neuber C, Schaaf S, Yuan L, Christ T, Vos MA, Eschenhagen T.
  • Basic research in cardiology.Basic Res Cardiol.2014 Nov;109(6):436. doi: 10.1007/s00395-014-0436-7. Epub 2014 Sep 11.
  • The assessment of proarrhythmic risks of drugs remains challenging. To evaluate the suitability of rat engineered heart tissue (EHT) for detecting proarrhythmic effects. We monitored drug effects on spontaneous contractile activity and, in selected cases, on action potentials (sharp microelectrode)
  • PMID 25209140
  • Using computational strategies to predict potential drugs for nasopharyngeal carcinoma.
  • Lan MY1, Yang WL, Lin KT, Lin JC, Shann YJ, Ho CY, Huang CY.
  • Head & neck.Head Neck.2014 Oct;36(10):1398-407. doi: 10.1002/hed.23464. Epub 2013 Nov 18.
  • BACKGROUND: Nasopharyngeal carcinoma (NPC) is a unique cancer. Refinement of current therapy by discovering potential drugs may be approached by several computational strategies.METHODS: We collected NPC genes from published microarray data and the literature. The NPC disease network was constructed
  • PMID 24038431
  • Molecular basis of non-mutational derepression of ramA in Klebsiella pneumoniae.
  • De Majumdar S1, Yu J1, Spencer J2, Tikhonova IG3, Schneiders T4.
  • The Journal of antimicrobial chemotherapy.J Antimicrob Chemother.2014 Oct;69(10):2681-9. doi: 10.1093/jac/dku203. Epub 2014 Jun 16.
  • OBJECTIVES: The ram locus, consisting of the romA-ramA genes, is repressed by the tetracycline-type regulator RamR, where regulation is abolished due to loss-of-function mutations within the protein or ligand interactions. The aim of this study was to determine whether the phenothiazines (chlorproma
  • PMID 25140579

和文文献

  • 薬剤性不整脈のリスクファクターに関する研究
  • 大中 博晶,大津 史子,矢野 玲子,金田 典雄,政田 幹夫,後藤 伸之
  • 医療薬学 33(10), 823-830, 2007-10-10
  • … In addition, disopyramide, ritodrine, miconazole, halothane, thioridazine and sodium thiopental were found to significantly raise the risk of drug-induced arrhythmia. …
  • NAID 110006419376
  • Simple and simultaneous determination for twelve phenothiazines in human serum by reversed-phase high-performance liquid chromatography
  • Tanaka Einosuke,Nakamura Takako,Terada Masaru,Shinozuka Tatsuo,Hashimoto Chikako,Kurihara Katsuyoshi,Honda Katsuya,田中 榮之介
  • Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 854(1), 116-120, 2007-07-01
  • … A high-performance liquid chromatographic method has been developed for the simultaneous analysis of the 12 phenothiazines (chlorpromazine, fluphenazine, levomepromazine, perazine, perphenazine, prochlorperazine, profenamine, promethazine, propericiazine, thioproperazine, thioridazine and trifluoperazine) in human serum using HPLC/UV. …
  • NAID 10025805017
  • IMPACT OF LEGISLATIVE CHANGES ON PATTERNS OF ANTIPSYCHOTIC PRESCRIBING AND SELF-POISONING IN SCOTLAND: 2000-06
  • Poon H.,Elliot V.,Bateman D. N. [他],WARING W. S.
  • Journal of toxicological sciences 32(1), 1-7, 2007-02-16
  • … This has led regulatory authorities in the United Kingdom to restrict the use of thioridazine. … These data indicate that legislative changes that restrict the use of thioridazine and other typical antipsychotics are associated with a measurable reduction in the number of hospital admissions due to overdose with these agents. …
  • NAID 110006204874

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リンク元チオリダジン

チオリダジン」

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thioridazine
thioridazinum
塩酸チオリダジン thioridazine hydrochloride
Mellaril
[[]]
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