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Selenium-enriched Agaricus bisporus increases expression and activity of glutathione peroxidase-1 and expression of glutathione peroxidase-2 in rat colon.

Maseko T, Howell K, Dunshea FR, Ng K.SourceDepartment of Agriculture and Food Systems, Melbourne School of Land & Environment, The University of Melbourne, Parkville, Victoria 3010, Australia.
Food chemistry.Food Chem.2014 Mar 1;146:327-33. doi: 10.1016/j.foodchem.2013.09.074. Epub 2013 Sep 21.
The effect of dietary supplementation with Se-enriched Agaricus bisporus on cytosolic gluthathione peroxidase-1 (GPx-1), gastrointestinal specific glutathione peroxidase-2 (GPx-2), thioredoxin reductase-1 (TrxR-1) and selenoprotein P (SeP) mRNA expression and GPx-1 enzyme activity in rat colon was e
PMID 24176350

Regulation of the human thioredoxin gene promoter and its key substrates: A study of functional and putative regulatory elements.

Hawkes HJ, Karlenius TC, Tonissen KF.SourceSchool of Biomolecular and Physical Sciences, and Eskitis Institute for Drug Discovery, Griffith University, Nathan, Qld 4111, Australia.
Biochimica et biophysica acta.Biochim Biophys Acta.2014 Jan;1840(1):303-14. doi: 10.1016/j.bbagen.2013.09.013. Epub 2013 Sep 13.
BACKGROUND: The thioredoxin system maintains redox balance through the action of thioredoxin and thioredoxin reductase. Thioredoxin regulates the activity of various substrates, including those that function to counteract cellular oxidative stress. These include the peroxiredoxins, methionine sulfox
PMID 24041992

The Thioredoxin Reductase-1 Inhibitor Aurothioglucose Attenuates Lung Injury and Improves Survival in a Murine Model of Acute Respiratory Distress Syndrome.

Britt RD, Velten M, Locy ML, Rogers LK, Tipple TE.SourceThe Research Institute at Nationwide Children's Hospital, Center for Perinatal Research, Columbus, Ohio, United States ; rodney.britt@nationwidechildrens.org.
Antioxidants & redox signaling.Antioxid Redox Signal.2013 Dec 2. [Epub ahead of print]
Aims Inflammation and oxygen toxicity increase free radical production and contribute to the development of acute respiratory distress syndrome (ARDS), a significant cause of morbidity and mortality in intensive care patients. We have previously reported increased glutathione (GSH) levels in lung ep
PMID 24295151

TAKETANI Yukiko,KINUGASA Kimihiro,FURUKAWA Shuhei,NAKAMURA Hajime,OTSUKI Ryoko,YASUDA Hisataka,FUJITA Tuyosi,KANZAKI Ken,MASUTANI Hiroshi,YODOI Junji
Bioscience, biotechnology, and biochemistry 75(10), 1872-1879, 2011-10-23
… Thioredoxin (TRX) catalyzes the reduction of disulfide bonds in proteins via the NADPH-dependent thioredoxin reductase system. … Treating with the yeast TRX-enriched extracts together with NADPH and yeast thioredoxin reductase enhanced the pepsin cleavage of β-lactoglobulin and ovomucoid (OM). …
NAID 10029872460

Selenite Reduction by the Thioredoxin System : Kinetics and Identification of Protein-Bound Selenide

TAMURA Takashi,SATO Kumi,KOMORI Kentaro,IMAI Takeshi,KUWAHARA Mitsuhiko,OKUGOCHI Takahiro,MIHARA Hisaaki,ESAKI Nobuyoshi,INAGAKI Kenji
Bioscience, biotechnology, and biochemistry 75(6), 1184-1187, 2011-06-23
… Selenite (SeO32−) assimilation into a bacterial selenoprotein depends on thioredoxin (trx) reductase in Esherichia coli, but the molecular mechanism has not been elucidated. … coli trx reductase (TrxB). …
NAID 10029328515