Fed Batch Fermentation and Purification Strategy for High Yield Production of Brucella melitensis Recombinant Omp 28 kDa Protein and its Application in Disease Diagnosis.
Karothia BS, Athmaram TN, D T, Ashu K, Tiwari S, Singh AK, Sathyaseelan K, Gopalan N.SourceBioprocess scale-up facility, Defence Research and Development Estt. Jhansi Road, Gwalior, 474002, India athmabiotech@gmail.com.
Protein and peptide letters.Protein Pept Lett.2013 Jul 1;20(7):731-40.
Brucellosis is a disease caused by bacteria belonging to the genus Brucella. It affects cattle, goat, sheep, dog and humans. The serodiagnosis of brucellosis involves detection of antibodies generated against the LPS or whole cell bacterial extracts, however these tests lack sensitivity and specific
Expression and purification of SenX3 from the Mycobacterium tuberculosis strain H37Rv in Escherichia coli.
Lv H, Hu L, Hu Q, Wei Q, Shen P.SourceCenter of Laboratory Medicine, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang 310014, P.R. China.
Molecular medicine reports.Mol Med Rep.2013 Jun;7(6):1960-4. doi: 10.3892/mmr.2013.1449. Epub 2013 Apr 26.
Infection with the bacterium Mycobacterium tuberculosis (MTB) causes tuberculosis, a pulmonary infection that may be fatal if left untreated. Misuse or mismanagement of tuberculosis drugs may lead to drug-resistant pathogen forms that are difficult to treat and contribute to a global health problem.