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  • MULTInational non-interventional study of patients with ST-segment elevation myocardial infarction treated with PRimary Angioplasty and Concomitant use of upstream antiplatelet therapy with prasugrel or clopidogrel - the European MULTIPRAC Registry.
  • Clemmensen P1, Grieco N2, Ince H3, Danchin N4, Goedicke J5, Ramos Y6, Schmitt J6, Goldstein P7; MULTIPRAC study investigators.
  • European heart journal. Acute cardiovascular care.Eur Heart J Acute Cardiovasc Care.2015 Jun;4(3):220-9. doi: 10.1177/2048872614547449. Epub 2014 Sep 2.
  • AIMS: Early initiation of dual antiplatelet therapy (DAPT) is guideline-recommended. MULTIPRAC was conducted to gain insights into the use patterns and outcomes of pre-hospital DAPT initiation with prasugrel or clopidogrel.METHODS AND RESULTS: MULTIPRAC is a multinational, multicentre, prospective r
  • PMID 25182465
  • Balancing the risks and benefits of dual platelet inhibition.
  • Keaney JF Jr1.
  • The New England journal of medicine.N Engl J Med.2015 May 7;372(19):1854-6. doi: 10.1056/NEJMe1502137. Epub 2015 Mar 14.
  • PMID 25773507
  • Efficacy and safety of P2Y12 inhibitors according to diabetes, age, gender, body mass index and body weight: Systematic review and meta-analyses of randomized clinical trials.
  • Zaccardi F1, Pitocco D2, Willeit P3, Laukkanen JA4.
  • Atherosclerosis.Atherosclerosis.2015 Apr 16;240(2):439-445. doi: 10.1016/j.atherosclerosis.2015.04.015. [Epub ahead of print]
  • OBJECTIVE: The efficacy of antiplatelet drugs may differ in specific patient subgroups. We aimed to assess the efficacy and safety of the P2Y12 inhibitors clopidogrel, ticlopidine, prasugrel, ticagrelor, and cangrelor according to diabetes status, age, gender, body mass index, and body weight.METHOD
  • PMID 25897998


  • Impact of Platelet Reactivity to Adenosine Diphosphate Before Implantation of Drug-Eluting Stents on Subsequent Adverse Cardiac Events in Patients With Stable Angina
  • MOTODA Chikaaki,UEDA Hironori,HAYASHI Yasuhiko,TOYOFUKU Mamoru,OKIMOTO Tomokazu,OTSUKA Masaya,TAMEKIYO Hiromichi,KAWASE Tomoharu,KIHARA Yasuki
  • Circulation journal : official journal of the Japanese Circulation Society 76(3), 641-649, 2012-02-25
  • … Background: Diverse pharmacological effects of anti-platelet thienopyridines due to individual differences in metabolism have been reported. …
  • NAID 10030129974
  • どこに差がある抗血小板薬
  • チクロピジンとアスピリンの併用治療を15日間休薬しても, 血小板機能が低下していた症例
  • 川崎 潤,小島 千佳,原 さやか,小山 薫,宮尾 秀樹,田中 健一
  • 日本臨床麻酔学会誌 = The Journal of Japan Society for Clinical Anesthesia 31(5), 877-883, 2011-09-15
  • NAID 10029770259


Thienopyridine. From Wikipedia, the free encyclopedia. Jump to: navigation, search. Ticlopidine · Clopidogrel · Prasugrel. Thienopyridines are a class of ADP receptor/P2Y12 inhibitors used for their anti-platelet activity.


Pharmacology of thienopyridines: rationale Thienopyridinesand thienopyridines inthienopyridines andMechanism of Action of Antiplatelet DrugsADP Receptor-Blocker Thienopyridines




チエノピリジン誘導体、抗血小板薬ADP受容体 P2Y12阻害薬