thienopyridines

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 経皮的冠動脈インターベンションのための抗血栓療法：一般的使用 antithrombotic therapy for percutaneous coronary intervention general use
2. 冠動脈ステント留置術後の抗血小板療法 antiplatelet therapy after coronary artery stenting
3. クロピドグレル耐性とクロピドグレル治療不奏効 clopidogrel resistance and clopidogrel treatment failure
4. 心血管疾患の二次および一次予防におけるアスピリンの利益とリスク benefits and risks of aspirin in secondary and primary prevention of cardiovascular disease
5. ST上昇型心筋梗塞における抗血小板剤 antiplatelet agents in acute st elevation myocardial infarction

MULTInational non-interventional study of patients with ST-segment elevation myocardial infarction treated with PRimary Angioplasty and Concomitant use of upstream antiplatelet therapy with prasugrel or clopidogrel - the European MULTIPRAC Registry.

Clemmensen P1, Grieco N2, Ince H3, Danchin N4, Goedicke J5, Ramos Y6, Schmitt J6, Goldstein P7; MULTIPRAC study investigators.
European heart journal. Acute cardiovascular care.Eur Heart J Acute Cardiovasc Care.2015 Jun;4(3):220-9. doi: 10.1177/2048872614547449. Epub 2014 Sep 2.
AIMS: Early initiation of dual antiplatelet therapy (DAPT) is guideline-recommended. MULTIPRAC was conducted to gain insights into the use patterns and outcomes of pre-hospital DAPT initiation with prasugrel or clopidogrel.METHODS AND RESULTS: MULTIPRAC is a multinational, multicentre, prospective r
PMID 25182465

Keaney JF Jr1.
The New England journal of medicine.N Engl J Med.2015 May 7;372(19):1854-6. doi: 10.1056/NEJMe1502137. Epub 2015 Mar 14.
PMID 25773507

Efficacy and safety of P2Y12 inhibitors according to diabetes, age, gender, body mass index and body weight: Systematic review and meta-analyses of randomized clinical trials.

Zaccardi F1, Pitocco D2, Willeit P3, Laukkanen JA4.
Atherosclerosis.Atherosclerosis.2015 Apr 16;240(2):439-445. doi: 10.1016/j.atherosclerosis.2015.04.015. [Epub ahead of print]
OBJECTIVE: The efficacy of antiplatelet drugs may differ in specific patient subgroups. We aimed to assess the efficacy and safety of the P2Y12 inhibitors clopidogrel, ticlopidine, prasugrel, ticagrelor, and cangrelor according to diabetes status, age, gender, body mass index, and body weight.METHOD
PMID 25897998

Impact of Platelet Reactivity to Adenosine Diphosphate Before Implantation of Drug-Eluting Stents on Subsequent Adverse Cardiac Events in Patients With Stable Angina

MOTODA Chikaaki,UEDA Hironori,HAYASHI Yasuhiko,TOYOFUKU Mamoru,OKIMOTO Tomokazu,OTSUKA Masaya,TAMEKIYO Hiromichi,KAWASE Tomoharu,KIHARA Yasuki
Circulation journal : official journal of the Japanese Circulation Society 76(3), 641-649, 2012-02-25
… Background: Diverse pharmacological effects of anti-platelet thienopyridines due to individual differences in metabolism have been reported. …
NAID 10030129974