関: theca cell tumor

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/07/06 08:03:59」(JST)

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Thecomas or theca cell tumors are benign ovarian neoplasms composed only of theca cells. Histogenetically they are classified as sex cord-stromal tumours.

They are typically estrogen-producing and they occur in older women (mean age 59; 84% after menopause). (They can, however, appear before menopause.^[1])

Sixty percent of patients present with abnormal uterine bleeding, and 20% have endometrial carcinoma.

Pathologic features

Low magnification micrograph of a thecoma showing compression of the ovarian cortex (right of image). H&E stain.

Grossly, the tumour is solid and yellow.

Grossly and microscopically, it consists of the ovarian cortex.

Microscopically, the tumour cells have abundant lipid-filled cytoplasm.

References

^ Okada I, Nakagawa S, Takemura Y, et al. (October 2004). "Ovarian thecoma associated in the first trimester of pregnancy". J. Obstet. Gynaecol. Res. 30 (5): 368–71. doi:10.1111/j.1447-0756.2004.00212.x. PMID 15327450.

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1. 卵巣の性索間質腫瘍：顆粒膜-間質細胞腫瘍 sex cord stromal tumors of the ovary granulosa stromal cell tumors
2. 卵巣の性索間質腫瘍の概要 overview of sex cord stromal tumors of the ovary
3. 卵巣の性索間質腫瘍：セルトリ・間質細胞腫瘍 sex cord stromal tumors of the ovary sertoli stromal cell tumors
4. Evaluation and management of postmenopausal hyperandrogenism
5. 精巣腫瘍の解剖学および病理 anatomy and pathology of testicular tumors

English Journal

New sonographic morphology score for the differentiation of malignant from benign ovarian tumors.

Shen ZY1, He AQ2, Xia GL1, Wu MF1, Li J1, Ding YS1.
The journal of obstetrics and gynaecology research.J Obstet Gynaecol Res.2016 Aug;42(8):1000-12. doi: 10.1111/jog.13009. Epub 2016 Apr 28.
AIM: The aim of this study was to explore the efficacy of a new sonographic morphology score (SMS) to differentiate malignant from benign ovarian tumors.METHODS: Data on 84 ovarian tumors in patients hospitalized in our hospital between 2013 and 2014 were retrospectively analyzed. We established a n
PMID 27125323

Ovarian thecoma with massive pleural effusion in postmenopausal women: A case report.

Ting Y1, Yang LI1, Juan Z1, Xing W1, Feng YX1.
Molecular and clinical oncology.Mol Clin Oncol.2016 Jun;4(6):1003-1005. Epub 2016 Apr 7.
Previous clinical reports of benign ovarian thecoma, associated with hydrothorax, are rare. The present study presents the case of a 58-year-old women exhibiting right massive pleural effusions and elevated cancer antigen (CA)125, and a pelvic ultrasound revealed a hypoechoic mass. An exploratory la
PMID 27284435

Vestibulodynia: A Multifactorial Syndrome: A Case Report.

Geynisman-Tan J, Ledger WJ.
The Journal of reproductive medicine.J Reprod Med.2016 May-Jun;61(5-6):287-9.
BACKGROUND: Vulvodynia is a difficult-to-treat, chronic, multifactorial malady that drastically lowers the quality of life of afflicted patients.CASE: A 68-year-old woman, who had been treated successfully for vulvodynia years before with medication, returned with a recurrence of vulvodynia symptoms
PMID 27424374

Japanese Journal

Testicular thecoma in an 11-year-old boy with nevoid basal-cell carcinoma syndrome (Gorlin syndrome).

Ueda Masakatsu,Kanematsu Akihiro,Nishiyama Hiroyuki,Yoshimura Koji,Watanabe Kenichiro,Yorifuji Tohru,Mikami Yoshiki,Kamoto Toshiyuki,Ogawa Osamu
Journal of pediatric surgery 45(3), 1-3, 2010-03
… We report a case of testicular thecoma in an 11-year-old Japanese boy with nevoid basal-cell carcinoma syndrome (Gorlin syndrome). … The tumor arose from the testis exophytically and was diagnosed as a thecoma histopathologically. … Ovarian thecoma-fibroma group tumors are closely associated with Gorlin syndrome or with abnormalities in PTCH, a candidate gene for the syndrome. …
NAID 120002515186