English Journal

Asn112 in Plasmodium falciparum glutathione S-transferase is essential for induced reversible tetramerization by phosphate or pyrophosphate.

Quesada-Soriano I1, Barón C1, Téllez-Sanz R1, García-Maroto F1, García-Fuentes L2.
Biochimica et biophysica acta.Biochim Biophys Acta.2014 Sep;1844(9):1427-36. doi: 10.1016/j.bbapap.2014.04.017. Epub 2014 May 2.
The glutathione S-transferase from Plasmodium falciparum presents distinct features which are absent from mammalian GST isoenzyme counterparts. Most apparent among these are the ability to tetramerize and the presence of a flexible loop. The loop, situated between the 113-119 residues, has been repo
PMID 24792386

Burkhardt P1, Grønborg M2, McDonald K3, Sulur T1, Wang Q4, King N5.
Molecular biology and evolution.Mol Biol Evol.2014 Sep;31(9):2342-55. doi: 10.1093/molbev/msu178. Epub 2014 Jun 3.
Reconstructing the evolution and ancestral functions of synaptic proteins promises to shed light on how neurons first evolved. The postsynaptic density (PSD) protein Homer scaffolds membrane receptors and regulates Ca(2+) signaling in diverse metazoan cell types (including neurons and muscle cells),
PMID 24899667

Biochemical and structural studies of the oligomerization domain of the Nipah virus phosphoprotein: evidence for an elongated coiled-coil homotrimer.

Blocquel D1, Beltrandi M, Erales J, Barbier P, Longhi S.
Virology.Virology.2013 Nov;446(1-2):162-72. doi: 10.1016/j.virol.2013.07.031. Epub 2013 Aug 28.
Nipah virus (NiV) is a recently emerged severe human pathogen that belongs to the Henipavirus genus within the Paramyxoviridae family. The NiV genome is encapsidated by the nucleoprotein (N) within a helical nucleocapsid that is the substrate used by the polymerase for transcription and replication.
PMID 24074578

Japanese Journal

尾上均,宇高ちひろ,山崎理紗 [他],中野麻衣子,武田朋子
西南女学院大学紀要 12, 81-87, 2008-00-00
イノシトール1,4,5-三リン酸(inositol 1,4,5-trisphosphate:IP_3)受容体は、小胞体膜上で四量体を形成することにより、IP_3が結合すると開口して、Ca^<2+>を細胞質へと動員するCa^<2+>放出チャネルとして機能するタンパク質である。IP_3受容体には現在までにI〜III型までの三つのタイプが同定されている。今回我々は、各タイプのIP …
NAID 110006978784