tetrameric

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tetramer

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/09/25 23:32:16」(JST)

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An example of a subunit, human hemoglobin. The protein's α and β subunits are coloured red and blue.

A tetramer (/ˈtɛtrəmər/) (tetra-, "four" + -mer, "parts") is an oligomer formed from four monomers or subunits. The associated propriety is called tetramery. An example is kobophenol A, a molecule formed from four stilbenoids monomers.

In biochemistry, it similarly refers to a biomolecule formed of four units, that are the same (homotetramer), i.e. as in Concanavalin A or different (heterotetramer), i.e. as in hemoglobin. Hemoglobin has 4 similar sub-units while immunoglobulins have 2 very different sub-units. The different sub-units may have each their own activity, such as binding biotin in avidin tetramers, or have a common biological property, such as the allosteric binding of oxygen in hemoglobin.

See also

• Tetrameric protein
• Tetramery (botany), tetramerous, a plant with four component parts in each whorls of its structure
• Tetramerium, a genus of plants belonging to the family Acanthaceae
• Cluster chemistry; atomic and molecular clusters

References

UpToDate Contents

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• 1. 肥満細胞：表面受容体とシグナル伝達 mast cells surface receptors and signal transduction
• 2. イブチリドの治療使用 therapeutic use of ibutilide
• 3. 小児における栄養状態の臨床検査および放射線学的評価 laboratory and radiologic evaluation of nutritional status in children
• 4. 赤血球細胞膜の動態および機構 red blood cell membrane dynamics and organization
• 5. 異常ヘモグロビン症の検査室診断 laboratory diagnosis of the hemoglobinopathies

English Journal

• Isolation of dimeric, trimeric, tetrameric and pentameric procyanidins from unroasted cocoa beans (Theobroma cacao L.) using countercurrent chromatography.

• Esatbeyoglu T1, Wray V2, Winterhalter P3.
• Food chemistry.Food Chem.2015 Jul 15;179:278-89. doi: 10.1016/j.foodchem.2015.01.130. Epub 2015 Feb 4.
• The main procyanidins, including dimeric B2 and B5, trimeric C1, tetrameric and pentameric procyanidins, were isolated from unroasted cocoa beans (Theobroma cacao L.) using various techniques of countercurrent chromatography, such as high-speed countercurrent chromatography (HSCCC), low-speed rotary
• PMID 25722166

• Structural modeling and patch-clamp analysis of pain-related mutation TRPA1-N855S reveal inter-subunit salt bridges stabilizing the channel open state.

• Zíma V1, Witschas K2, Hynkova A3, Zímová L2, Barvík I1, Vlachova V4.
• Neuropharmacology.Neuropharmacology.2015 Jun;93:294-307. doi: 10.1016/j.neuropharm.2015.02.018. Epub 2015 Feb 25.
• The ankyrin transient receptor potential channel TRPA1 is a polymodal sensor for noxious stimuli, and hence a promising target for treating chronic pain. This tetrameric six-transmembrane segment (S1-S6) channel can be activated by various pungent chemicals, such as allyl isothiocyanate or cinnamald
• PMID 25724085

• Novel insights in mammalian catalase heme maturation: Effect of NO and thioredoxin-1.

• Chakravarti R1, Gupta K2, Majors A1, Ruple L1, Aronica M1, Stuehr DJ3.
• Free radical biology & medicine.Free Radic Biol Med.2015 May;82:105-13. doi: 10.1016/j.freeradbiomed.2015.01.030. Epub 2015 Feb 4.
• Catalase is a tetrameric heme-containing enzyme with essential antioxidant functions in biology. Multiple factors including nitric oxide (NO) have been shown to attenuate its activity. However, the possible impact of NO in relation to the maturation of active catalase, including its heme acquisition
• PMID 25659933

Japanese Journal

• 膜内KcsAカリウムチャネルの原子間力顕微鏡による構造と動態解析

• 角野 歩,山本 大輔,炭竈 享司 [他],岩本 真幸,出羽 毅久,老木 成稔
• 生物物理 55(1), 005-010, 2015
• … In the open conformation, the open pore at the center of the tetrameric channel was resolved, and the protrusion was substantially shortened relative to the closed conformation. …
• NAID 130004794734

• チタン(IV) 三置換Dawson型ポリ酸塩単量体とそれを用いたNH₄+イオン内包テトラポッド型四量体の合成

• 松木 悠介,Matsuki Yusuke,星野 貴弘,Hoshino Takahiro,増田 佳奈,Masuda Kana,松井 敬祐,Matsui Keisuke,力石 紀子,Chikaraishi Kasuga Noriko,松永 諭,Matsunaga Satoshi,野宮 健司,Nomiya Kenji
• Science Journal of Kanagawa University 25, 69-72, 2014-06-30
• The monomeric tri-Ti(IV)-substituted Dawson polyoxometalate (POM), Na12[P2W15Ti3O62]•NaCl•6H2O, was synthesized by basic hydrolysis of the bridging Dawson tetramer with an encapsulated chloride ion, N …
• NAID 120005556263

• Catalytic domain surface residues mediating catecholamine inhibition in tyrosine hydroxylase

• Briggs Gabrielle D.,Bulley Jesse,Dickson Phillip W.
• The journal of biochemistry 155(3), 183-193, 2014-03
• NAID 40020021459

Related Links

• Tetrameric - definition of tetrameric by The Free Dictionary

tet·ra·mer (tĕt′rə-mər) n. A polymer consisting of four identical monomers. [tetra-+ (poly)mer.] tet′ra·mer′ic (-mĕr′ĭk) adj. tetrameric ... A tetrameric 70 kDa galactose specific lectin was purified using two step simple purification protocol ...

• Tetramer | Definition of Tetramer by Merriam-Webster

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heterotetramer

「homotetrameric」

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homotetramer

「tetramer」

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• 四量体、テトラマー

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tetrameric