tetracyclines antibiotics

テトラサイクリン系抗菌薬

WordNet

1. a chemical substance derivable from a mold or bacterium that can kill microorganisms and cure bacterial infections; "when antibiotics were first discovered they were called wonder drugs" (同)antibiotic drug
2. of or relating to antibiotic drugs
3. an antibiotic (trade name Achromycin) derived from microorganisms of the genus Streptomyces and used broadly to treat infections (同)Achromycin

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1. 抗生物質(ペニシリン,ストレプトマイシンなど) / 抗生[物質]の

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• 1. テトラサイクリン tetracyclines
• 2. マクロライド系剤、アミノグリコシド、テトラサイクリン、クリンダマイシン、およびメトロニダゾールに対する過敏反応 hypersensitivity reactions to macrolides aminoglycosides tetracyclines clindamycin and metronidazole
• 3. 尋常性ざ瘡の治療 treatment of acne vulgaris
• 4. 腸球菌における抗菌薬耐性の機構 mechanisms of antibiotic resistance in enterococci
• 5. Necrobiosis lipoidica

English Journal

• Determination of veterinary antibiotics in bovine urine by liquid chromatography-tandem mass spectrometry.

• Chiesa L1, Nobile M1, Arioli F2, Britti D3, Trutic N4, Pavlovic R5, Panseri S1.
• Food chemistry.Food Chem.2015 Oct 15;185:7-15. doi: 10.1016/j.foodchem.2015.03.098. Epub 2015 Mar 28.
• A follow-up of antibiotics (tetracyclines, fluoroquinolones, cephalosporins, penicillins and amphenicols) in the bovine urine is important for two reasons: to understand if they are still present in organism, and whether their occurrence in urine might be considered as an environmental risk. A valid
• PMID 25952835

• Simultaneous determination of 38 veterinary antibiotic residues in raw milk by UPLC-MS/MS.

• Han RW1, Zheng N2, Yu ZN1, Wang J1, Xu XM2, Qu XY2, Li SL2, Zhang YD2, Wang JQ3.
• Food chemistry.Food Chem.2015 Aug 15;181:119-26. doi: 10.1016/j.foodchem.2015.02.041. Epub 2015 Feb 14.
• A selective and rapid method has been developed to determine, simultaneously, 38 veterinary antibiotic residues in raw milk by ultra-high-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). One milliliter of raw milk was diluted with 0.5 mL water and 3 mL acetonitrile, then puri
• PMID 25794729

• Removal of tetracyclines from swine manure at full-scale activated sludge treatment plants.

• Montes N1, Otero M, Coimbra RN, Méndez R, Martín-Villacorta J.
• Environmental technology.Environ Technol.2015 Aug;36(15):1966-73. doi: 10.1080/09593330.2015.1018338. Epub 2015 Mar 10.
• The purpose of this study was to investigate the fate of three tetracyclines (TCs), namely oxytetracycline (OTC), chlortetracycline (CTC) and doxycycline (DC) at two different full-scale swine manure-activated sludge treatment plants. Throughout treatment, OTC, CTC and DC were removed by 71-76%, 75-
• PMID 25672878

Japanese Journal

• Characterization of Erysipelothrix rhusiopathiae strains isolated from acute swine erysipelas outbreaks in Eastern China

• ZOU Yao,ZHU Xiaoming,MUHAMMAD Hassan Mushtaq,JIANG Ping,LI Yufeng
• Journal of Veterinary Medical Science 77(6), 653-660, 2015
• … All the field and attenuated strains were highly sensitive to β-lactam antibiotics, tetracyclines and macrolides. …
• NAID 130005085862

• Characterization of Erysipelothrix rhusiopathiae strains isolated from acute swine erysipelas outbreaks in Eastern China

• ZOU Yao,ZHU Xiaoming,MUHAMMAD Hassan Mushtaq,JIANG Ping,LI Yufeng
• Journal of Veterinary Medical Science advpub(0), 2015
• … All the field and attenuated strains were highly sensitive to β-lactam antibiotics, tetracyclines and macrolides. …
• NAID 130004781086

• Community-acquired Pneumonia Caused by Macrolide-resistant Mycoplasma pneumoniae in Adults

• Hanada Shigeo,Morozumi Miyuki,Takahashi Yui,Mochizuki Sayaka,Sato Toshitaka,Suzuki Shinko,Uruga Hironori,Takaya Hisashi,Miyamoto Atsushi,Morokawa Nasa,Ubukata Kimiko,Kishi Kazuma
• Internal Medicine 53(15), 1675-1678, 2014
• … We herein describe a case of community-acquired pneumonia caused by macrolide-resistant Mycoplasma pneumoniae (MRMP) in an adult who responded poorly to macrolide antibiotics, progressively deteriorated to acute respiratory failure and then responded effectively to a fluoroquinolone. … In seven of the eight cases of MRMP initially treated with macrolides, the patients did not improve, and a marked improvement was observed only after the antibiotic regimen was modified to include fluoroquinolones or tetracyclines. …
• NAID 130004678363

Related Links

• Tetracyclines - antibiotics - UK Essays | Part of All Answers Ltd

Tetracyclines are a large family of broad-spectrum antibiotics. ... The essay examples we publish have been submitted to us by students. The essays are the students' work and are not examples of our expert essay writers' work.

• Tetracycline antibiotics - definition of Tetracycline antibiotics ...

Tetracyclines Definition Tetracyclines are medicines that kill certain infection-causing microorganisms. Purpose Tetracyclines are called "broad-spectrum" antibiotics, because they can be used to treat a wide variety of infections.

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★リンクテーブル★

リンク元	「テトラサイクリン系抗菌薬」
関連記事	「tetracycline」「tetracyclines」

「テトラサイクリン系抗菌薬」

　　[★]

英

tetracyclines antibiotics

関

抗菌薬

• first aid step1 2006 p.170

特徴

• 静菌的作用
• 抗菌薬の1st choiceになりやすい

構造

• 六員環が4つ連結した構造　→　日光過敏との関連

作用機序

• 30Sリボソームに結合し、リボソームへのアミノアシルtRNAの結合を阻害→蛋白合成阻害

抗菌スペクトル

• グラム陽性菌、グラム陰性菌、リケッチア、マイコプラズマ、アメーバ

動態

• 酸に強く経口投与可能
• 上部消化管から吸収される
• 脳脊髄液には移行しづらい。
• 胆汁、尿にそのまま排泄される

禁忌

• 妊婦

副作用

• 歯牙の着色：妊婦、授乳中の女性、8歳以下の子供には避ける
• 日光過敏
• 催奇性：骨の発育阻害
• 菌交代症

テトラサイクリン系抗菌薬

• テトラサイクリン tetracycline
• [[]] chlortetracycline
• オキシテトラサイクリン oxytetracycline
• [[]] demeclocycline
• [[]] rolitetracycline
• [[]] methacycline
• ドキシサイクリン doxycycline
• ミノサイクリン minocycline

「tetracycline」

　　[★] テトラサイクリン, TC 　

「tetracyclines」

　　[★] テトラサイクリン系抗菌薬