tenecteplase

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/09/19 19:20:06」(JST)

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英文文献

  • In intermediate-risk acute PE, tenecteplase plus heparin reduced hemodynamic decompensation but increased stroke.
  • Akl EA, Guyatt GH.
  • Annals of internal medicine.Ann Intern Med.2014 Sep 16;161(6):JC8. doi: 10.7326/0003-4819-161-6-201409160-02008.
  • PMID 25222420
  • Time Is Penumbra: Imaging, Selection and Outcome. The Johann Jacob Wepfer Award 2014.
  • Davis S1, Donnan GA.
  • Cerebrovascular diseases (Basel, Switzerland).Cerebrovasc Dis.2014 Sep 16;38(1):59-72. [Epub ahead of print]
  • The foundation of modern therapy for ischaemic stroke involves reperfusion of the ischaemic penumbra and salvage of threatened but potentially viable brain tissue. Work on imaging of the penumbra and clinical trials using penumbral evaluation or selection have been a major focus of our collaborative
  • PMID 25227260
  • Intracoronary thrombolysis in patients with ST-segment elevation myocardial infarction presenting with massive intraluminal thrombus and failed aspiration.
  • Boscarelli D1, Vaquerizo B2, Miranda-Guardiola F3, Arzamendi D1, Tizon H3, Sierra G3, Delgado G1, Fantuzzi A3, Estrada D1, Garcia-Picart J1, Cinca J1, Serra A1.
  • European heart journal. Acute cardiovascular care.Eur Heart J Acute Cardiovasc Care.2014 Sep;3(3):229-36. doi: 10.1177/2048872614527008. Epub 2014 Mar 17.
  • AIM: Massive intracoronary thrombus is associated with adverse procedural results including failed aspiration and unfavourable reperfusion. In this scenario the best treatment remains unknown. We aim to evaluate the effect of low dose intracoronary thrombolysis in patients with ST-segment elevation
  • PMID 24637066

和文文献

  • Quantitative analysis of Tenecteplase in rat plasma samples using LC-MS/MS as an alternative for ELISA
  • BUSCHER B. A. P.,GERRITSEN H.,VAN SCHOLL I.,CNUBBEN N. H. P.,BRULL L. P.
  • Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 852(1), 631-634, 2007-06-01
  • NAID 10025803191
  • A pilot dose-escalation safety study of tenecteplase in acute ischemic stroke

関連リンク

Tenecteplase (TNK) is an enzyme used as a thrombolytic drug. Tenecteplase is a tissue plasminogen activator (tPA) produced by recombinant DNA technology using an established mammalian cell line (Chinese hamster ovary cells).
2012年3月21日 ... recombinant tissue plasminogen activatorである、alteplaseは、急性卒中にて ベネフィットがあるが、理想からほど遠く、不完全で、再潅流として遅い。遺伝子工学的に 作られたtenecteplaseは、tPAであり、リスク・ベネフィットのバランスから ...

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