WordNet

any specific behavior; "they avoided all recreational activity"
(chemistry) the capacity of a substance to take part in a chemical reaction; "catalytic activity"
an enzyme in eukaryotic cells that can add telomeres to the ends of chromosomes after they divide

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1. 前立腺癌の分子生物学 molecular biology of prostate cancer
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5. 特発性肺線維症の病因 pathogenesis of idiopathic pulmonary fibrosis

The NVL gene confers risk for both major depressive disorder and schizophrenia in the Han Chinese population.

Wang M1, Chen J2, He K3, Wang Q4, Li Z1, Shen J1, Wen Z1, Song Z1, Xu Y4, Shi Y5.
Progress in neuro-psychopharmacology & biological psychiatry.Prog Neuropsychopharmacol Biol Psychiatry.2015 Oct 1;62:7-13. doi: 10.1016/j.pnpbp.2015.04.001. Epub 2015 Apr 17.
NVL (nuclear VCP (valosin containing protein)/p97-Like), a member of the AAA-ATPase (ATPases associated with various cellular activities) family, encodes a novel hTERT (human telomerase reverse transcriptase)-interacting protein NVL2 which is a telomerase component essential for holoenzyme assembly.
PMID 25891250

Cloning and molecular characterization of telomerase reverse transcriptase (TERT) and telomere length analysis of Peromyscus leucopus.

Zhao X1, Ueda Y2, Kajigaya S2, Alaks G3, Desierto MJ2, Townsley DM2, Dumitriu B2, Chen J2, Lacy RC3, Young NS2.
Gene.Gene.2015 Aug 15;568(1):8-18. doi: 10.1016/j.gene.2015.05.013. Epub 2015 May 9.
Telomerase reverse transcriptase (TERT) is the catalytic subunit of telomerase complex that regulates telomerase activity to maintain telomere length for all animals with linear chromosomes. As the Mus musculus (MM) laboratory mouse has very long telomeres compared to humans, a potential alternative
PMID 25962353

Telomere length and telomerase in a well-characterized sample of individuals with major depressive disorder compared to controls.

Simon NM1, Walton ZE2, Bui E3, Prescott J4, Hoge E3, Keshaviah A5, Schwarz N5, Dryman T5, Ojserkis RA5, Kovachy B5, Mischoulon D3, Worthington J3, DeVivo I6, Fava M3, Wong KK7.
Psychoneuroendocrinology.Psychoneuroendocrinology.2015 Aug;58:9-22. doi: 10.1016/j.psyneuen.2015.04.004. Epub 2015 Apr 13.
BACKGROUND: Leukocyte telomere length (LTL) is a marker of cellular turnover and oxidative stress. Studies suggest major depressive disorder (MDD) is associated with oxidative stress, but examinations of MDD and LTL have yielded mixed results, likely because of differences in measurement methods and
PMID 25932992

Qi Xiaodong,Li Yang,Honda Shinji,Hoffmann Steve,Marz Manja,Mosig Axel,Podlevsky Joshua D.,Stadler Peter F.,Selker Eric U.,Chen Julian J.-L.
Nucleic Acids Research 41, 450-462, 2013-01-00
… Telomerase is a ribonucleoprotein with an intrinsictelomerase RNA (TER) component. … crassa and Schizosaccharomyces pombe telomerasereconstituted in vitro, and showed thatthe two RNA core domains in both systems canreconstitute activity in trans as two separateRNA fragments. … crassa telomerase synthesizes TTAGGG repeatswith high processivity, a common attribute of vertebratetelomerase. …
NAID 120005323239

The hTERT Promoter Enhances the Antitumor Activity of an Oncolytic Adenovirus under a Hypoxic Microenvironment

Hashimoto Yuuri,Tazawa Hiroshi,Teraishi Fuminori,Kojima Toru,Watanabe Yuichi,Uno Futoshi,Yano Shuya,Urata Yasuo,Kagawa Shunsuke,Fujiwara Toshiyoshi
PLoS ONE 7(6), 2012-06-15
… We previously generated a tumor-specific replication-competent oncolytic adenovirus (OBP-301: Telomelysin), in which the human telomerase reverse transcriptase (hTERT) promoter drives viral E1 expression. … Since the promoter activity of the hTERT gene has been shown to be upregulated by hypoxia, we hypothesized that, under hypoxic conditions, the antitumor effect of OBP-301 with the hTERT promoter would be more efficient than that of the wild-type adenovirus 5 (Ad5). …
NAID 120005232484

Stem cells in asexual reproduction of Enchytraeus japonensis (Oligochaeta, Annelid): Proliferation and migration of neoblasts

Sugio Mutsumi,Yoshida-Noro Chikako,Ozawa Kaname [他],Tochinai Shin
Development, Growth & Differentiation 54(4), 439-450, 2012-05-00
… We have also shown that neoblasts have stem cell characteristics by expressing Ej-vlg2 and by the activity of telomerase during regeneration. … Telomerase activity was high in the early stage of regeneration and correlated with the proliferation activity in the neoblast lineage of mesodermal stem cells. …
NAID 120005228679