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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/12/14 10:04:37」(JST)

English Journal

Hedgehog pathway overexpression in pancreatic cancer is abrogated by new-generation taxoid SB-T-1216.

Mohelnikova-Duchonova B1,2, Kocik M3, Duchonova B4, Brynychova V1,5, Oliverius M3, Hlavsa J6, Honsova E7, Mazanec J8, Kala Z6, Ojima I9, Hughes DJ10, Doherty JE11, Murray HA11, Crockard MA11, Lemstrova R2, Soucek P1.
The pharmacogenomics journal.Pharmacogenomics J.2016 Aug 30. doi: 10.1038/tpj.2016.55. [Epub ahead of print]
The Hedgehog pathway is one of the major driver pathways in pancreatic ductal adenocarcinoma. This study investigated prognostic importance of Hedgehog signaling pathway in pancreatic cancer patients who underwent a radical resection. Tumors and adjacent non-neoplastic pancreatic tissues were obtain
PMID 27573236

Diving Into Cabazitaxel's Mode of Action: More Than a Taxane for the Treatment of Castration-Resistant Prostate Cancer Patients.

Mellado B1, Jimenez N2, Marin-Aguilera M2, Reig O2.
Clinical genitourinary cancer.Clin Genitourin Cancer.2016 Aug;14(4):265-70. doi: 10.1016/j.clgc.2015.12.030. Epub 2015 Dec 28.
Prostate cancer is a molecularly heterogeneous disease, and mechanisms of action of taxanes and potential mechanisms of resistance are not clearly defined. Taxanes are microtubule-stabilizing agents resulting in the slowing or blocking of mitosis at the metaphase-anaphase transition and induction of
PMID 26827258

Response to docetaxel and cisplatin induction chemotherapy of locally advanced head and neck squamous cell carcinoma: a multicenter, non-comparative, open-label interventional pilot study.

Noronha V1, Goswami C2, Patil S3, Joshi A1, Patil VM1, Murthy V4, Arya S5, Juvekar S5, Goud S3, Prabhash K3.
The Journal of laryngology and otology.J Laryngol Otol.2016 Jul 26:1-10. [Epub ahead of print]
BACKGROUND: Docetaxel, cisplatin plus 5-fluorouracil is an efficacious induction regimen but is more toxic than cisplatin plus 5-fluorouracil. This study aimed to determine whether docetaxel and cisplatin without 5-fluorouracil maintains efficacy while decreasing toxicity.METHODS: A multicenter non-
PMID 27456399

石野貴久,寺田珠実,鮫島正浩,鴨田重裕
東京大学農学部演習林報告 126, 2012-02-25
… We examined the presence of TXS, BAPT and T a H, thought to be a key enzyme for taxoid production, by dot blot hybridization for first screening of taxol-producing fungi. … As a result we were able to obtain the sequences of three taxol biosynthetic pathway genes from Cordyceps dipterigene and from this we concluded that Cordyceps dipterigene has the ability of taxoid production. …
NAID 120003988591

加茂理英,大霜智子,梅香路綾乃,村上克彦,石井正光
Skin Cancer 26(2), 201-205, 2011
頭部脈管肉腫治療は，近年縮小手術か無手術で，放射線療法とタキサン系抗がん剤併用が主流である。自験例は，症例1は軽度認知症の独居88歳女性，症例2は認知症と脳梗塞後片麻痺の既往の85歳女性である。病理組織学的に頭部脈管肉腫と診断し，初期治療に放射線療法を行い腫瘤は軽快した。症例1は初期治療後，左耳下腺転移しドセタキセル投与を試みるも骨髄抑制で継続できず初診後25ヵ月で死亡した。症例2は，通院でドセタ …
NAID 130001480086