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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/02/19 19:00:52」(JST)

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/10/16 23:16:49」(JST)

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  • Distinct Roles for Intestinal Epithelial Cell-Specific Hdac1 and Hdac2 in the Regulation of Murine Intestinal Homeostasis.
  • Gonneaud A1, Turgeon N1, Boudreau F1, Perreault N1, Rivard N1, Asselin C1.
  • Journal of cellular physiology.J Cell Physiol.2016 Feb;231(2):436-48. doi: 10.1002/jcp.25090.
  • The intestinal epithelium responds to and transmits signals from the microbiota and the mucosal immune system to insure intestinal homeostasis. These interactions are in part conveyed by epigenetic modifications, which respond to environmental changes. Protein acetylation is an epigenetic signal reg
  • PMID 26174178
  • Effects of Gender and Estrogen Receptors on Iron-Induced Brain Edema Formation.
  • Xie Q1,2, Xi G1, Keep RF1, Hua Y3.
  • Acta neurochirurgica. Supplement.Acta Neurochir Suppl.2016;121:341-5. doi: 10.1007/978-3-319-18497-5_59.
  • Our previous studies have shown that female mice have less brain edema and better recovery in neurological deficits after intracerebral hemorrhage (ICH) and that 17β-estradiol treatment in male mice markedly reduces ICH-induced brain edema. In this study, we investigated the role of gender and the
  • PMID 26463972
  • Tamoxifen-Containing Eye Drops Successfully Trigger Cre-Mediated Recombination in the Entire Eye.
  • Schlecht A1, Leimbeck SV2, Tamm ER3, Braunger BM4.
  • Advances in experimental medicine and biology.Adv Exp Med Biol.2016;854:495-500. doi: 10.1007/978-3-319-17121-0_66.
  • Embryonic lethality in mice with targeted gene deletion is a major issue that can be circumvented by using Cre-loxP-based animal models. Various inducible Cre systems are available, e.g. such that are activated following tamoxifen treatment, and allow deletion of a specific target gene at any desire
  • PMID 26427451


  • Hepatoprotective effect of tamoxifen on steatosis and non-alcoholic steatohepatitis in mouse models
  • Miyashita Taishi,Toyoda Yasuyuki,Tsuneyama Koichi [他]
  • The Journal of toxicological sciences 37(5), 931-942, 2012-10
  • NAID 40019458156
  • Oxidative stress in the testis induced by tamoxifen and its effects on early embryo development in isogenic mice
  • LEE Sunghak,LEE Myeong-Seop,PARK Joonghoon,ZHANG Jin Yu,JIN Dong Il
  • Journal of toxicological sciences 37(4), 675-679, 2012-08-01
  • NAID 10030502072


Tamoxifen is also used sometimes to induce ovulation (egg production) in women who do not produce eggs but wish to become pregnant. Tamoxifen is also sometimes used to treat McCune-Albright syndrome (MAS; a ...
Tamoxifen blocks the actions of estrogen and is used to treat and prevent some types of breast cancer. Learn about side effects, interactions and indications. ... Tamoxifen side effects Get emergency medical help if you have signs of ...



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