tacrolimus

出典: meddic

タクロリムス

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/06/18 22:21:29」(JST)

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英文文献

  • Enhancement of tacrolimus productivity in Streptomyces tsukubaensis by the use of novel precursors for biosynthesis.
  • Turło J, Gajzlerska W, Klimaszewska M, Król M, Dawidowski M, Gutkowska B.SourceDepartment of Drug Technology and Pharmaceutical Biotechnology, Medical University of Warsaw, 1 Banacha St, 02-097 Warsaw, Poland. Electronic address: jadwiga.turlo@wum.edu.pl.
  • Enzyme and microbial technology.Enzyme Microb Technol.2012 Dec 10;51(6-7):388-95. doi: 10.1016/j.enzmictec.2012.08.008. Epub 2012 Aug 30.
  • In this report the optimization of biosynthesis of tacrolimus, the immunosupressant widely used in transplantology and dermatology was described. The enhancement of the productivity of Streptomyces tsukubaensis strain was achieved by development of new precursors of tacrolimus biosynthesis, which sh
  • PMID 23040396
  • Extracellular factors and immunosuppressive drugs influencing insulin secretion of murine islets.
  • Auer VJ, Janas E, Ninichuk V, Eppler E, Weiss TS, Kirchner S, Otto AM, Stangl MJ.SourceInstitute of Medical Engineering, Technische Universität München (IMETUM), Garching Center for Liver Cell Research, Department of Pediatrics and Adolescent Medicine, University of Regensburg Hospital Hepacult GmbH, Biopark Regensburg, Regensburg Chirurgische Klinik und Poliklinik, Transplantationszentrum, Klinikum Großhadern, Ludwig-Maximilians-Universität, München, Germany Research Group Neuro-endocrine-immune Interactions, Anatomisches Institut, Zentrum für Integrative Humanphysiologie (ZIHP), Universität Zürich, Zürich, Switzerland.
  • Clinical and experimental immunology.Clin Exp Immunol.2012 Nov;170(2):238-247. doi: 10.1111/j.1365-2249.2012.04645.x.
  • Approximately 60% of transplanted islets undergo apoptosis within the first week post-transplantation into the liver attributed to poor engraftment, immune rejection and toxicity of immunosuppressive drugs. Understanding how extracellular matrix (ECM) components, immunosuppressive drugs and proinfla
  • PMID 23039895

和文文献

  • Preparation of High-Payload, Prolonged-Release Biodegradable Poly(lactic-co-glycolic acid)-Based Tacrolimus Microspheres Using the Single-Jet Electrospray Method
  • Preparation of High-Payload, Prolonged-Release Biodegradable Poly(lactic-co-glycolic acid)-Based Tacrolimus Microspheres Using the Single-Jet Electrospray Method
  • タクロリムス固体分散体製剤の効率的な0.1 mg希釈散調製方法の確立

関連リンク

Tacrolimus comes as a capsule to take by mouth. It is usually taken twice a day. Space your doses 12 hours apart, and take tacrolimus at the same times every day. Follow the directions on your prescription label carefully, and ask ...
INTRODUCTION Cyclosporine and tacrolimus selectively inhibit calcineurin, thereby impairing the transcription of interleukin (IL)-2 and several other cytokines in T lymphocytes. Calcineurin inhibitors have been mainstays of ...

関連画像

Tacrolimus; Tacrolimus capsules, USP Tacrolimus. Causes, symptoms, treatment tacrolimus what is tacrolimus tacrolimus  of age is Tacrolimus ointment; Protopic1MG RDY 526 Pill - tacrolimus 1 mgtacrolimus 1mg lab. pisa regaladas


★リンクテーブル★
リンク元免疫抑制薬」「タクロリムス
拡張検索tacrolimus-binding protein」「tacrolimus hydrate」「tacrolimus ointment」「tacrolimus-binding protein 1A

免疫抑制薬」

  [★]

immunosuppressive drug, immunosuppressant

免疫抑制薬

作用機序

56kDa immunophilinに結合 (GOO.1596)
56kDa immunophilinはHSP70, HSP90と共にglucocorticoid receptosに結合している。

再生不良性貧血に対する治療薬として



タクロリムス」

  [★]

tacrolimus
プログラフタリムスプロトピック Protopicグラセプター
tacrolimus ointment
免疫抑制剤シクロスポリンタクロリムス水和物
  • 放線菌から分離されたマクロライド系の物質
  • シクロスポリンより低濃度で免疫抑制の作用をもつ
  • 腎毒性がある




tacrolimus-binding protein」

  [★]

FK506-binding proteinFKBP


tacrolimus hydrate」

  [★]

FK-506FK506tacrolimus


tacrolimus ointment」

  [★] タクロリムス。タクロリムス水和物軟膏


tacrolimus-binding protein 1A」

  [★]




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