synthetic penicillin

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  • Kidney and haemostasis. A (personal) time-journey.
  • Andrassy K.
  • Hamostaseologie.Hamostaseologie.2014 Nov 4;35(1). [Epub ahead of print]
  • Renal insufficiency is characterized by thrombocytopathy, caused by the accumulation of water soluble and protein bound waste products of protein metabolism, which are not adequately eliminated by the kidney. The kidneys also excrete drugs and their metabolites, which accumulate if dosages are not a
  • PMID 25366713
  • Diaryl-Substituted Azolylthioacetamides: Inhibitor Discovery of New Delhi Metallo-β-Lactamase-1 (NDM-1).
  • Zhang YL1, Yang KW, Zhou YJ, LaCuran AE, Oelschlaeger P, Crowder MW.
  • ChemMedChem.ChemMedChem.2014 Nov;9(11):2445-8. doi: 10.1002/cmdc.201402249. Epub 2014 Jul 22.
  • The emergence and spread of antibiotic-resistant pathogens is a global public health problem. Metallo-β-lactamases (MβLs) such as New Delhi MβL-1 (NDM-1) are principle contributors to the emergence of resistance because of their ability to hydrolyze almost all known β-lactam antibiotics includin
  • PMID 25048031


  • 脂肪酸生合成におけるエノイルACP還元酵素 FabI と FabK 阻害による抗菌薬の探索
  • 小澤 智宏,高畑 祥,北川 英男
  • 有機合成化学協会誌 70(3), 265-275, 2012-03-01
  • … pneumoniae, including penicillin-resistant strains, were 1 and 4µg/mL, respectively. …
  • NAID 10030481778
  • Synthetic Lethality of the lytE cwlO Genotype in Bacillus subtilis Is Caused by Lack of D,L-Endopeptidase Activity at the Lateral Cell Wall
  • Hashimoto Masayuki,Ooiwa Seika,Sekiguchi Junichi
  • JOURNAL OF BACTERIOLOGY 194(4), 796-803, 2012-02
  • … Although peptidoglycan biosynthesis by penicillin-binding proteins is well studied, few studies have described peptidoglycan disassembly, which is necessary for a dynamic structure that allows cell growth. … However, the forced expression of LytF or CwlS, which are paralogs of LytE, did not suppress lytE cwlO synthetic lethality. …
  • NAID 80022308460


In terms of public health, penicillin is pretty much the best thing since sliced bread. Its medical benefits were famously discovered in 1928 by Scottish bacteriologist Alexander Fleming from a piece of moldy bread. Penicillin was ...
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拡張検索broad spectrum semisynthetic penicillin

broad spectrum semisynthetic penicillin」

  [★] 広域スペクトルペニシリン



  • adj.
  • 合成の、合成的な、総合的な

WordNet   license wordnet

「systematic combining of root and modifying elements into single words」

WordNet   license wordnet

「a compound made artificially by chemical reactions」
synthetic substance

WordNet   license wordnet

「involving or of the nature of synthesis (combining separate elements to form a coherent whole) as opposed to analysis; "limnology is essentially a synthetic science composed of elements...that extend well beyond the limits of biology"- P.S.Welch」

WordNet   license wordnet

「of a proposition whose truth value is determined by observation or facts; "`all men are arrogant'' is a synthetic proposition"」

WordNet   license wordnet

「not genuine or natural; "counterfeit rhetoric that flourishes when passions are synthetic"- George Will」

PrepTutorEJDIC   license prepejdic

「総合の,統合的な / 合成の,人造の / にせの,作りごとの / (言語が)総合的な(統語的関係を表すのに,独立した語より屈折形を広く用いるもの) / 合成品,人造物」


  [★] ペニシリン

WordNet   license wordnet

「any of various antibiotics obtained from Penicillium molds (or produced synthetically) and used in the treatment of various infections and diseases」

PrepTutorEJDIC   license prepejdic