出典: meddic


R-SNARE protein

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  • Phosphatidylserine-Dependent Catalysis of Stalk and Pore Formation by Synaptobrevin JMR-TMD Peptide.
  • Tarafdar PK1, Chakraborty H1, Bruno MJ1, Lentz BR2.
  • Biophysical journal.Biophys J.2015 Nov 3;109(9):1863-72. doi: 10.1016/j.bpj.2015.08.051.
  • Although the importance of a SNARE complex in neurotransmitter release is widely accepted, there exist different views on how the complex promotes fusion. One hypothesis is that the SNARE complex's ability to bring membranes into contact is sufficient for fusion, another points to possible roles of
  • PMID 26536263
  • Vesicular Synaptobrevin/VAMP2 Levels Guarded by AP180 Control Efficient Neurotransmission.
  • Koo SJ1, Kochlamazashvili G1, Rost B2, Puchkov D1, Gimber N1, Lehmann M3, Tadeus G1, Schmoranzer J3, Rosenmund C2, Haucke V4, Maritzen T5.
  • Neuron.Neuron.2015 Oct 21;88(2):330-44. doi: 10.1016/j.neuron.2015.08.034. Epub 2015 Sep 24.
  • Neurotransmission depends on synaptic vesicle (SV) exocytosis driven by soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex formation of vesicular synaptobrevin/VAMP2 (Syb2). Exocytic fusion is followed by endocytic SV membrane retrieval and the high-fidelity reform
  • PMID 26412491
  • Tissue Plasminogen Activator Expression Is Restricted to Subsets of Excitatory Pyramidal Glutamatergic Neurons.
  • Louessard M1, Lacroix A2,3,4, Martineau M5, Mondielli G6, Montagne A1, Lesept F1, Lambolez B2,3,4, Cauli B2,3,4, Mothet JP6, Vivien D7, Maubert E1.
  • Molecular neurobiology.Mol Neurobiol.2015 Sep 16. [Epub ahead of print]
  • Although the extracellular serine protease tissue plasminogen activator (tPA) is involved in pathophysiological processes such as learning and memory, anxiety, epilepsy, stroke, and Alzheimer's disease, information about its regional, cellular, and subcellular distribution in vivo is lacking. In the
  • PMID 26377106


  • Ca2+-independent syntaxin binding to the C2B effector region of synaptotagmin
  • Masumoto Toshio,Suzuki Koichiro,Ohmori Iori,Michiue Hiroyuki,Tomizawa Kazuhito,Fujimura Atsushi,Nishiki Tei-ichi,Matsui Hideki
  • Molecular and Cellular Neuroscience 49(1), 1-8, 2012-01
  • … SNARE complexes comprising syntaxin 1, 25-kDa synaptosomal-associated protein (SNAP-25), and synaptobrevin 2 were coprecipitzted with synaptotagmin I in the presence of ethylene glycol tetraacetic acid. … Syntaxin, but not SNAP-25 and synaptobrevin, bound to synaptotagmin in a Ca2+-independent manner, and the binding was abolished in the presence of 1 M NaCl. …
  • NAID 120005425639
  • Factors regulating the abundance and localization of synaptobrevin in the plasma membrane
  • Proc. Natl. Acad. Sci. USA 103, 11399-11404, 2006
  • NAID 30016238189
  • RNAi-mediated gene silencing to assess the role of synaptobrevin and cystatin in tick blood feeding
  • KARIM S.
  • Biochemical and Biophysical Research Communications 334, 1336-1342, 2005
  • NAID 30017846126


Myobloc - Mechanism of Action 3D Medical Animation, AutoFill with Cell Paper recipe applied to a single vesicle and minor overlaps ... The World News (WN) Network, has created this privacy statement in order to demonstrate our ...
[VAMP; vesicle-associated membrane protein] [synaptobrevin isotypes 1-2] VAMP。VAMP/synaptobrevin familyに含まれる全てのタンパク質は共通の構造をもっていてsと呼ばれる。v- and t-SNAREsに分類されるときは、その合成機関に ...



リンク元R-SNARE protein
拡張検索synaptobrevin 1」「synaptobrevin 2」「synaptobrevin 3




R-SNARE protein」




synaptobrevin 1」



VAMP-1、VAMP1vesicle-associated membrane protein 1

synaptobrevin 2」



VAMP-2、VAMP2vesicle-associated membrane protein 2

synaptobrevin 3」



VAMP3vesicle-associated membrane protein 3