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1. 原発性および転移性脳腫瘍患者における痙攣発作 seizures in patients with primary and metastatic brain tumors
2. 心雑音および心音の鑑別診断における生理学的および薬理学的手法 physiologic and pharmacologic maneuvers in the differential diagnosis of heart murmurs and sounds
3. 痙攣発作およびてんかんの病態生理 pathophysiology of seizures and epilepsy
4. 冬眠心筋の評価 evaluation of hibernating myocardium
5. コカイン乱用による心血管系合併症の評価およびマネージメント evaluation and management of the cardiovascular complications of cocaine abuse

Dopamine and norepinephrine receptors participate in methylphenidate enhancement of in vivo hippocampal synaptic plasticity.

Jenson D1, Yang K2, Acevedo-Rodriguez A1, Levine A1, Broussard JI1, Tang J3, Dani JA4.
Neuropharmacology.Neuropharmacology.2015 Mar;90:23-32. doi: 10.1016/j.neuropharm.2014.10.029. Epub 2014 Nov 11.
Attention-deficit hyperactive disorder (ADHD) is the most commonly studied and diagnosed psychiatric disorder in children. Methylphenidate (MPH, e.g., Ritalin) has been used to treat ADHD for over 50 years. It is the most commonly prescribed treatment for ADHD, and in the past decade it was the drug
PMID 25445492

Gating of hippocampal output by β-adrenergic receptor activation in the pilocarpine model of epilepsy.

Grosser S1, Hollnagel JO2, Gilling KE1, Bartsch JC1, Heinemann U2, Behr J3.
Neuroscience.Neuroscience.2015 Feb 12;286:325-37. doi: 10.1016/j.neuroscience.2014.11.055. Epub 2014 Dec 10.
Norepinephrine acting via β-adrenergic receptors (β-ARs) plays an important role in hippocampal plasticity including the subiculum which is the principal target of CA1 pyramidal cells and which controls information transfer from the hippocampus to other brain regions including the neighboring pres
PMID 25498224

Methamphetamine differentially affects BDNF and cell death factors in anatomically defined regions of the hippocampus.

Galinato MH1, Orio L2, Mandyam CD3.
Neuroscience.Neuroscience.2015 Feb 12;286:97-108. doi: 10.1016/j.neuroscience.2014.11.042. Epub 2014 Nov 26.
Methamphetamine exposure reduces hippocampal long-term potentiation (LTP) and neurogenesis and these alterations partially contribute to hippocampal maladaptive plasticity. The potential mechanisms underlying methamphetamine-induced maladaptive plasticity were identified in the present study. Expres
PMID 25463524

Extracellular ATP modulates synaptic plasticity induced by activation of metabotropic glutamate receptors in the hippocampus

,
Biomedical Research 36(1), 1-9, 2015
… Synaptic plasticity is believed to be a cellular mechanism for memory formation in the brain. … It has been known that the metabotropic glutamate receptor (mGluR) is required for persistent forms of memory and induction of synaptic plasticity. … Application of mGluR agonists induces synaptic plasticity in the absence of electrical conditioning stimulation, such as high or low frequency stimulation. …
NAID 130004903878

Dexmedetomidine suppresses long-term potentiation in the hippocampal CA1 field of anesthetized rats

Ito Kato Ryoko,Tachibana Kaori,Hashimoto Toshikazu,Takita Koichi,Morimoto Yuji
Journal of anesthesia 28(6), 828-832, 2014-12
… The aim of this study was to evaluate the effect of dexmedetomidine (DEX) on hippocampal synaptic activity in vivo. … The results of our in vivo study reveal that sedative doses of DEX impaired the induction of hippocampal long-term potentiation (LTP). …
NAID 120005606027

Metaplastic Regulation of the Median Raphe Nucleus via Serotonin 5-HT₁A Receptor on Hippocampal Synaptic Plasticity Is Associated With Gender-Specific Emotional Expression in Rats