English Journal

Ketone bodies effectively compete with glucose for neuronal acetyl-CoA generation in rat hippocampal slices.

Valente-Silva P1, Lemos C1, Köfalvi A1, Cunha RA1,2, Jones JG1,3.
NMR in biomedicine.NMR Biomed.2015 Sep;28(9):1111-6. doi: 10.1002/nbm.3355. Epub 2015 Jul 15.
Ketone bodies can be used for cerebral energy generation in situ, when their availability is increased as during fasting or ingestion of a ketogenic diet. However, it is not known how effectively ketone bodies compete with glucose, lactate, and pyruvate for energy generation in the brain parenchyma.
PMID 26174755

Kushida N1, Fry CH2.
BJU international.BJU Int.2015 Jul 24. doi: 10.1111/bju.13240. [Epub ahead of print]
OBJECTIVES: To characterise separately the pharmacological profiles of spontaneous contractions from the mucosa and detrusor layers of the bladder wall and to describe the relationship in mucosa between adenosine triphosphate (ATP) release and spontaneous contractions.MATERIALS AND METHODS: Spontane
PMID 26207752

The gut microbiome restores intrinsic and extrinsic nerve function in germ-free mice accompanied by changes in calbindin.

McVey Neufeld KA1, Perez-Burgos A, Mao YK, Bienenstock J, Kunze WA.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.Neurogastroenterol Motil.2015 May;27(5):627-36. doi: 10.1111/nmo.12534. Epub 2015 Mar 2.
BACKGROUND: The microbiome is essential for normal myenteric intrinsic primary afferent neuron (IPAN) excitability. These neurons control gut motility and modulate gut-brain signaling by exciting extrinsic afferent fibers innervating the enteric nervous system via an IPAN to extrinsic fiber sensory
PMID 25727007