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  • Superantigens Subvert the Neutrophil Response To Promote Abscess Formation and Enhance Staphylococcus aureus Survival In Vivo.
  • Xu SX1, Gilmore KJ2, Szabo PA1, Zeppa JJ1, Baroja ML3, Haeryfar SM4, McCormick JK5.
  • Infection and immunity.Infect Immun.2014 Sep;82(9):3588-98. doi: 10.1128/IAI.02110-14. Epub 2014 Jun 9.
  • Staphylococcus aureus is a versatile bacterial pathogen that produces T cell-activating toxins known as superantigens (SAgs). Although excessive immune activation by SAgs can induce a dysregulated cytokine storm as a component of what is known as toxic shock syndrome (TSS), the contribution of SAgs
  • PMID 24914221
  • [Staphylococcal toxic shock syndrome after breast surgery].
  • Pelissier A1, Dumesnil J2, Levy R3, Charron C4, Rouzier R5.
  • Journal de gynécologie, obstétrique et biologie de la reproduction.J Gynecol Obstet Biol Reprod (Paris).2014 Sep;43(7):526-9. doi: 10.1016/j.jgyn.2014.02.003. Epub 2014 Mar 14.
  • The surgical site infection occurs within 30 days after surgery. It is the most common complication of surgery, with a rate of 1 to 5% without antibiotic prophylaxis and less than 1% with antibiotic prophylaxis. The toxic shock syndrome (TSS) is a dramatic complication. We report the case 39-year-ol
  • PMID 24636869
  • Staphylococcus aureus β-toxin Production is Common in Strains With the β-toxin Gene Inactivated by Bacteriophage.
  • Salgado-Pabón W, Herrera A, Vu BG, Stach CS, Merriman JA, Spaulding AR, Schlievert PM.
  • The Journal of infectious diseases.J Infect Dis.2014 Sep 1;210(5):784-92. doi: 10.1093/infdis/jiu146. Epub 2014 Mar 11.
  • BACKGROUND: Staphylococcus aureus causes life-threatening infections, including infective endocarditis, sepsis, and pneumonia. β-toxin is a sphingomyelinase encoded for by virtually all S. aureus strains and exhibits human immune cell cytotoxicity. The toxin enhances S. aureus phenol-soluble moduli
  • PMID 24620023


  • 好酸球性副鼻腔炎の病態 (特集 好酸球性副鼻腔炎の病態と治療)
  • 石戸谷 淳一,佐久間 康徳,塩野 理 [他]
  • 臨床免疫・アレルギー科 55(4), 429-434, 2011-04-00
  • NAID 40018833136
  • 感染症や乾癬におけるIL-23とTh17細胞
  • 鑑 慎司
  • 日本臨床免疫学会会誌 = Japanese journal of clinical immunology 34(1), 13-19, 2011-02-28
  •   IL-23は樹状細胞などの抗原提示細胞が産生する.そしてIL-23はTh17細胞への分化を誘導し,Th17細胞の増殖,維持に必要である.Th17細胞は好中球を遊走するケモカイン,抗菌ペプチド,および他の炎症性サイトカインの発現を増強する.IL-23とTh17細胞が正常に機能する状態では宿主はカンジダ,黄色ブドウ球菌,溶連菌等の微生物を駆除できるが,Th17細胞が欠損した状態 …
  • NAID 10029431563
  • Protective eff ect of intranasal vaccination with nontoxic mutant TSST-1 against Staphylococcus aureus infection
  • Narita Kouji,Hu Dong-Liang,Tsuji Takao [他],Nakane Akio
  • 弘前醫學 59(Suppl), S227-S234, 2007-00-00
  • … Toxic shocksyndrome toxin 1( TSST-1) is one of superantigens secreted by S. …
  • NAID 110006603003