WordNet

a silvery soft waxy metallic element of the alkali metal group; occurs abundantly in natural compounds (especially in salt water); burns with a yellow flame and reacts violently in water; occurs in sea water and in the mineral halite (rock salt) (同)Na, atomic number 11

PrepTutorEJDIC

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 肝臓の有機アニオン輸送能および薬物代謝能の検査 tests of the livers capacity to transport organic anions and metabolize drugs
2. 抱合型高ビリルビン血症関連の遺伝性疾患 inherited disorders associated with conjugated hyperbilirubinemia
3. 肝細胞障害を検出するための肝臓生化学検査 liver biochemical tests that detect injury to hepatocytes
4. 肝臓の合成能の検査（アルブミン、凝固因子、プロトロンビン時間など） tests of the livers biosynthetic capacity eg albumin coagulation factors prothrombin time
5. 血清ビリルビン定量の臨床的側面 clinical aspects of serum bilirubin determination

Investigation of Fluorescein Derivatives as Substrates of Organic Anion Transporting Polypeptide (OATP) 1B1 To Develop Sensitive Fluorescence-Based OATP1B1 Inhibition Assays.

Izumi S1, Nozaki Y1, Komori T1, Takenaka O2, Maeda K3, Kusuhara H3, Sugiyama Y4.
Molecular pharmaceutics.Mol Pharm.2016 Jan 7. [Epub ahead of print]
Organic anion transporting polypeptide (OATP) 1B1 plays an important role in the hepatic uptake of various drugs. Because OATP1B1 is a site of drug-drug interactions (DDIs), evaluating the inhibitory potential of drug candidates on OATP1B1 is required during drug development. For establishing a high
PMID 26696140

Role of OAT4 in Uptake of Estriol Precursor 16α-Hydroxydehydroepiandrosterone Sulfate Into Human Placental Syncytiotrophoblasts From Fetus.

Tomi M1, Eguchi H1, Ozaki M1, Tawara T1, Nishimura S1, Higuchi K1, Maruyama T1, Nishimura T1, Nakashima E1.
Endocrinology.Endocrinology.2015 Jul;156(7):2704-12. doi: 10.1210/en.2015-1130. Epub 2015 Apr 28.
Estriol biosynthesis in human placenta requires the uptake of a fetal liver-derived estriol precursor, 16α-hydroxydehydroepiandrosterone sulfate (16α-OH DHEAS), by placental syncytiotrophoblasts at their basal plasma membrane (BM), which faces the fetal circulation. The aim of this work is to iden
PMID 25919187

The potential drug-drug interactions of ginkgolide B mediated by renal transporters.

Qiu Z1, Wang L, Dai Y, Ren W, Jiang W, Chen X, Li N.
Phytotherapy research : PTR.Phytother Res.2015 May;29(5):662-7. doi: 10.1002/ptr.5294. Epub 2015 Jan 15.
Ginkgolide B (GB) is a selective and strong antagonist of platelet-activating factor with great benefits in CNS diseases treatment. The renal excretion constitutes the predominant secretory pathway of GB. Here, we investigated the potential role of renal drug transporters in GB urinary excretion. Th
PMID 25589475

津田寛,古屋清一,近藤芳夫
日本消化器病学会雑誌 81(8), 1773-1780, 1984
… To study the effect of taurocholate on sulfobromophthalein (BSP) excretion in the rats with relieved biliary obstruction, 42 Wistar rats were divided into two groups; …
NAID 130001064001

宮田康司,古賀俊逸,山本匡介,井林博,牧野勲
肝臓 23(5), 540-545, 1982
… Plasma clearance of unconjugated bilirubin, sulfobromophthalein sodium (BSP), indocyanine green (ICG) and ursodeoxycholic acid (UDCA) were studied in father and son cases with Rotor's syndrome. …
NAID 130000878418