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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/02/16 19:28:32」(JST)
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Sulfaguanidine
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Systematic (IUPAC) name |
4-amino-N-[amino(imino)methyl]benzenesulfonamide |
Clinical data |
AHFS/Drugs.com |
International Drug Names |
Legal status |
?
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Identifiers |
CAS number |
57-67-0 |
ATC code |
A07AB03 |
PubChem |
CID 5324 |
ChemSpider |
5133 |
UNII |
15XQ8043FN Y |
KEGG |
D02437 Y |
Chemical data |
Formula |
C7H10N4O2S |
Molecular mass |
214.2449 g/mol |
SMILES
- C1=CC(=CC=C1N)S(=O)(=O)NC(=N)N
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InChI
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InChI=1S/C7H10N4O2S/c8-5-1-3-6(4-2-5)14(12,13)11-7(9)10/h1-4H,8H2,(H4,9,10,11)
Key:BRBKOPJOKNSWSG-UHFFFAOYSA-N
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Y (what is this?) (verify) |
Sulfaguanidine is a sulfonamide.
Antidiarrheals, intestinal anti-inflammatory and anti-infective agents (A07)
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Rehydration |
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Intestinal anti-infectives |
- Antibiotics
- Amphotericin B
- Colistin
- Fidaxomicin
- Kanamycin
- Natamycin
- Neomycin
- Nystatin
- Paromomycin
- Polymyxin B
- Rifaximin
- Streptomycin
- Vancomycin
- Sulfonamides
- Phthalylsulfathiazole
- Succinylsulfathiazole
- Sulfaguanidine
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Intestinal adsorbents |
- Charcoal
- Bismuth
- Pectin
- Kaolin
- Crospovidone
- Attapulgite
- Diosmectite
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Antipropulsives (opioids) |
- Opium tincture (laudanum)
- Codeine
- Morphine
- Camphorated opium tincture (paregoric)
- crosses BBB: Diphenoxylate (Diphenoxylate/atropine)
- Difenoxin
- does not cross BBB: Loperamide
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Intestinal anti-inflammatory agents |
- corticosteroids acting locally
- Prednisolone
- Hydrocortisone
- Prednisone
- Betamethasone
- Tixocortol
- Budesonide
- Beclometasone
- antiallergic agents, excluding corticosteroids
- aminosalicylic acid and similar agents
- Sulfasalazine
- Mesalazine
- Olsalazine
- Balsalazide
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Antidiarrheal micro-organisms |
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Other antidiarrheals |
- Albumin tannate
- Ceratonia
- Crofelemer
- Octreotide
- Racecadotril
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Description |
- Anatomy
- Physiology
- Development
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Disease |
- Congenital
- Neoplasms and cancer
- Inflammatory bowel disease
- Gluten sensitivity
- Other
- Symptoms and signs
- Blood tests
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Treatment |
- Procedures
- Drugs
- anabolic steroids
- antacids
- diarrhoea and infection
- bile and liver
- functional gastrointestinal disorders
- laxatives
- peptic ulcer and reflux
- vomiting
- other
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General Synonyms: sulfaguanidine, 4-amino-N-(aminoiminomethyl)benzenesulfonamide, 4-amino-N-guanylbenzenesulfonamide, abiguanil, aterian, ganidan, guamide, guanicil, guanidan, resulfon, ruocid, shigatix, suganyl, sulfoguanidine, sulfoguenil, sulgin Use: veterinary drug Molecular formula: C7H10N4O2S CAS No: 57-67-0 EINECS No: 200-345-9 Physical data Appearance: white powder Melting point: Boiling point: Vapour density: Vapour pressure: Density (g cm-3): Flash point: Explosion limits: Autoignition temperature: Water solubility:
Stability Stable. Incompatible with strong oxidizing agents.
Toxicology Eye, respiratory and skin irritant. May be harmful - toxicology not fully investigated.. Toxicity data (The meaning of any toxicological abbreviations which appear in this section is given here.)
Risk phrases (The meaning of any risk phrases which appear in this section is given here.) R36 R37 R38.
Transport information (The meaning of any UN hazard codes which appear in this section is given here.) Non-hazardous for air, sea and road freight. Personal protection Safety glasses, adequate ventilation. Safety phrases (The meaning of any safety phrases which appear in this section is given here.) S26 S36.
English Journal
- Purification and characterization of carbonic anhydrase from Ağrı Balık Lake trout gill (Salmo trutta labrax) and effects of sulfonamides on enzyme activity.
- Demirdag R1, Comakli V, Kuzu M, Yerlikaya E, Şentürk M.
- Journal of biochemical and molecular toxicology.J Biochem Mol Toxicol.2015 Mar;29(3):123-8. doi: 10.1002/jbt.21675. Epub 2014 Oct 26.
- Carbonic anhydrase (CA) was purified from Ağrı Balık Lake trout gill (fCA) by affinity chromatography on a sepharose 4B-tyrosine-sulfanilamide column. The fCA enzyme was purified with about a 303.9 purification factor, a specific activity 4130.4 EU (mg-protein)(-1), and a yield of 79.3 by using s
- PMID 25345690
- Preparation and application of sulfaguanidine-imprinted polymer on solid-phase extraction of pharmaceuticals from water.
- Mutavdžić Pavlović D1, Nikšić K2, Livazović S2, Brnardić I3, Anžlovar A4.
- Talanta.Talanta.2015 Jan;131:99-107. doi: 10.1016/j.talanta.2014.06.065. Epub 2014 Aug 1.
- The molecularly imprinted polymers (MIPs) with sulfaguanidine as a template, methacrylic acid, 4-vinylpyridine, and 2-hydroxyethyl methacrylate as functional monomers, ethylene glycol dimethacrylate as a cross-linker and 2,2'-azobis-isobutyronitrile as an initiator have been prepared through the cro
- PMID 25281079
- The sensitivity of Daphnia magna and Daphnia curvirostris to 10 veterinary antibacterials and to some of their binary mixtures.
- Dalla Bona M1, Di Leva V2, De Liguoro M3.
- Chemosphere.Chemosphere.2014 Nov;115:67-74. doi: 10.1016/j.chemosphere.2014.02.003. Epub 2014 Mar 12.
- Aim of this study was to evaluate the suitability of Daphnia curvirostris for the acute toxicity test usually performed on Daphnia magna, and to compare the sensitivity of the two species toward 10 antibacterials [enrofloxacin (EFX), ciprofloxacin(CPX), sulfaguanidine (SGD), sulfadiazine (SDZ), sulf
- PMID 24630458
Japanese Journal
- Determination of Hydration kinetics of Sulfaguanidine Anhydrate in Aqueous Solution by Calorimetry
- Determination of Hydration Kinetics of Sulfaguanidine Anhydrate in Aqueous Solution by Calorimetry.
- Relationship between Sulfaguanidine Resistance and Increased Cellulose Production in Acetobacter xylinum BPR3001E
- Bioscience, biotechnology, and biochemistry 62(6), 1234-1236, 1998-06-23
- NAID 110002679242
Related Links
- Sigma-Aldrich offers Sigma-S8751, Sulfaguanidine for your research needs. Find product specific information including CAS, MSDS, protocols and references. ... Application Sulfaguanidine is used to block the synthesis of ...
- sulfaguanidine [sul″fah-gwan´ĭ-dēn] a sulfonamide antibacterial used in treatment of gastrointestinal infections, especially bacillary dysentery, administered orally. sulfaguanidine the first sulfonamide designed to treat enteric infections.
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