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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/11/16 05:26:58」(JST)
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Succinylsulfathiazole
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Systematic (IUPAC) name |
4-oxo-4-({4-[(1,3-thiazol-2-ylamino)sulfonyl]phenyl}amino)butanoic acid
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Identifiers |
ATC code |
A07AB04 |
PubChem |
CID: 5315 |
UNII |
RSS8647O4S Y |
KEGG |
D07060 Y |
ChEMBL |
CHEMBL1484857 |
Chemical data |
Formula |
C13H13N3O5S2 |
Molecular mass |
355.38942 g/mol |
Y (what is this?) (verify) |
Succinylsulfathiazole is a sulfonamide. It is also spelled as succinylsulphathiazole. It is a white or yellow-white crystalline powder. It dissolves in aqueous solutions of alkali hydroxides and carbonates but is very slightly soluble in water.
It is classified as ultra long acting drug. About 95% of the drug remains in the intestine and only 5% is hydrolyzed, slowly, to Sulfathiazole and is absorbed.
The drug is used for its antibacterial activity in the GIT. The dose is 10g - 20g daily in divided doses.
Antidiarrheals, intestinal anti-inflammatory and anti-infective agents (A07)
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Rehydration |
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Intestinal anti-infectives |
- Antibiotics
- Amphotericin B
- Colistin
- Fidaxomicin
- Kanamycin
- Natamycin
- Neomycin
- Nystatin
- Paromomycin
- Polymyxin B
- Rifaximin
- Streptomycin
- Vancomycin
- Sulfonamides
- Phthalylsulfathiazole
- Succinylsulfathiazole
- Sulfaguanidine
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Intestinal adsorbents |
- Charcoal
- Bismuth
- Pectin
- Kaolin
- Crospovidone
- Attapulgite
- Diosmectite
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Antipropulsives (opioids) |
- Opium tincture (laudanum)
- Codeine
- Morphine
- Camphorated opium tincture (paregoric)
- crosses BBB: Diphenoxylate (Diphenoxylate/atropine)
- Difenoxin
- does not cross BBB: Eluxadoline
- Loperamide
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Intestinal anti-inflammatory agents |
- corticosteroids acting locally
- Prednisolone
- Hydrocortisone
- Prednisone
- Betamethasone
- Tixocortol
- Budesonide
- Beclometasone
- antiallergic agents, excluding corticosteroids
- aminosalicylic acid and similar agents
- Sulfasalazine
- Mesalazine
- Olsalazine
- Balsalazide
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Antidiarrheal micro-organisms |
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Other antidiarrheals |
- Albumin tannate
- Ceratonia
- Crofelemer
- Octreotide
- Racecadotril
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Index of digestion
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Description |
- Anatomy
- Physiology
- Development
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Disease |
- Congenital
- Neoplasms and cancer
- Inflammatory bowel disease
- Gluten sensitivity
- Other
- Symptoms and signs
- Blood tests
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Treatment |
- Procedures
- Drugs
- anabolic steroids
- antacids
- diarrhoea and infection
- bile and liver
- functional gastrointestinal disorders
- laxatives
- peptic ulcer and reflux
- nausea and vomiting
- other
- Surgery
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UpToDate Contents
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Japanese Journal
- Succinylsulfathiazole投与によるモルモット腸内菌数の変動及び之に伴う腸管淋巴装置並びに腸間膜淋巴節の形態学的変化に関する研究
Related Links
- Find patient medical information for succinylsulfathiazole on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. ... Selected from data included with permission and copyrighted by ...
- Buy Succinylsulfathiazole (CAS 116-43-8), a product for proteomics research applications, from Santa Cruz. Molecular Formula: C13H13N3O5S2, MW: 355.39 ... 試験・研究用以外には使用しないでください。 臨床及び体外診断には使用 ...
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