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出血,(特に)大量出血 / 多量に出血する
皮下の

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1. 出血性疾患の疑いのある成人患者へのアプローチapproach to the adult with a suspected bleeding disorder [show details]
… hemarthroses are typical of coagulation factor deficiencies. Bleeding challenge – A bleeding challenge is an event that would normally cause bleeding, such as a dental extraction, surgery, delivery, or trauma …
2. 産後出血の概要overview of postpartum hemorrhage [show details]
… defined by the volume of blood loss (ie, estimated blood loss ≥500 mL after vaginal birth or ≥1000 mL after cesarean delivery), this diagnosis is problematic because bleeding may not be visible externally …
3. 出血症状を有する小児に対するアプローチapproach to the child with bleeding symptoms [show details]
… or adolescent presenting with either overt bruising or bleeding or with a history of increased bleeding. Thrombocytopenia and specific bleeding disorders, including hemophilia and von Willebrand disease …
4. 人工心臓弁における抗血栓療法：出血および侵襲的手技のマネージメントantithrombotic therapy for prosthetic heart valves management of bleeding and invasive procedures [show details]
… procedure. When subcutaneous LMWH is used, the last dose is administered 24 hours before the procedure. Use of postoperative bridging with heparin is individualized based upon the risk of bleeding and risk …
5. 成人における急性下部消化管出血に対するアプローチapproach to acute lower gastrointestinal bleeding in adults [show details]
… Acute lower gastrointestinal (GI) bleeding refers to blood loss of recent onset originating from the colon. The causes of acute lower GI bleeding may be grouped into several categories: anatomic (diverticulosis) …

English Journal

Submucosal tunneling endoscopic resection for submucosal tumors of the esophagogastric junction originating from the muscularis propria layer: a feasibility study (with videos).

Wang XY1, Xu MD, Yao LQ, Zhou PH, Pleskow D, Li QL, Zhang YQ, Chen WF, Zhong YS.
Surgical endoscopy.Surg Endosc.2014 Jun;28(6):1971-7. doi: 10.1007/s00464-014-3420-2. Epub 2014 Feb 11.
BACKGROUND: The esophagogastric junction (EGJ) is a difficult location for endoscopic resection due to its narrow lumen and sharp angle. Potential increased risks of perforation and mediastinal infection exist, especially for submucosal tumors (SMTs) originating from the muscularis propria (MP) laye
PMID 24515260

Subcutaneous enoxaparin for therapeutic anticoagulation in hemodialysis patients.

Pon TK1, Dager WE2, Roberts AJ3, White RH4.
Thrombosis research.Thromb Res.2014 Jun;133(6):1023-8. doi: 10.1016/j.thromres.2014.03.036. Epub 2014 Mar 24.
BACKGROUND: Information regarding dosing of low-molecular-weight heparins (LMWH) for therapeutic anticoagulation in hemodialysis (HD) patients is limited. The aim of this study was to retrospectively compare the safety and efficacy of enoxaparin versus unfractionated heparin (UFH) for therapeutic an
PMID 24718051

Prevention effect of orally active heparin conjugate on cancer-associated thrombosis.

Al-Hilal TA1, Alam F2, Park JW3, Kim K4, Kwon IC4, Ryu GH5, Byun Y6.
Journal of controlled release : official journal of the Controlled Release Society.J Control Release.2014 May 23. pii: S0168-3659(14)00330-7. doi: 10.1016/j.jconrel.2014.05.027. [Epub ahead of print]
Thrombogenesis is a major cause of morbidity and mortality in cancer patients. Prophylaxis with low-molecular-weight heparin (LMWH) is recommended for cancer patients, but requires non-parenteral delivery methods for long-term treatments. In this study, we sought to generate a new oligomeric-bile ac
PMID 24862320

Japanese Journal

A severe drug induced hepatitis caused by a dietary supplement "Nin-niku Ran-oh" made from garlic and egg yolk

岡本欣也,三好謙一,木科学,藤瀬幸,加藤順,徳永志保,的野智光,法正恵子,大山賢治,岡野淳一,前田直人,孝田雅彦,村脇義和
肝臓 53(11), 748-753, 2012
… A 60 years old woman who took some dietary supplements developed appetite loss, general fatigue, jaundice and subcutaneous hemorrhage together with a > …
NAID 130003343840

von Recklinghausen 病に合併した Vater 乳頭部ソマトスタチノーマの1例

川口章吾,山形亮,高橋誠司,齋藤太郎,村田有志,八木橋操六,福田眞作
日本消化器内視鏡学会雑誌 = Gastroenterological endoscopy 53(5), 1435-1440, 2011-05-20
症例は36歳女性．タール便を排泄後に意識消失をきたし当院へ救急搬送された．全身の皮膚にCafé-au-lait斑を認めた．上部消化管内視鏡検査で十二指腸下行脚に腫瘍性病変を認め，中心の潰瘍からは出血を認めた．保存的治療後，幽門輪温存膵頭十二指腸切除術が施行されたが，腫瘍は膵頭部にまで浸潤しており，♯13aのリンパ節に転移を認めた．腫瘍は免疫組織学的検査の結果ソマトスタチノーマであると診断 …
NAID 10029092470