WordNet

the 19th letter of the Roman alphabet (同)s
any of several hemolysins derived from strains of streptococcus

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sulfurの化学記号 / {略}South[ern]

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/02/13 01:33:41」(JST)

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Streptolysin is a streptococcal hemolytic exotoxin.^[1]^[2]

Types include streptolysin O (SLO), which is oxygen-labile, and streptolysin S (SLS), which is oxygen-stable.^[3]

An antibody, antistreptolysin O, can be detected in an antistreptolysin O titre.

Streptolysin O is hemolytically active only in a reversibly reduced state, unlike streptolysin S, which is stable in the presence of oxygen. Another difference is that that SLO is antigenic, while SLS is not antigenic due to its small size.

References

^ "streptolysin" at Dorland's Medical Dictionary
^ Streptolysin at the US National Library of Medicine Medical Subject Headings (MeSH)
^ Sierig G, Cywes C, Wessels MR, Ashbaugh CD (January 2003). "Cytotoxic effects of streptolysin o and streptolysin s enhance the virulence of poorly encapsulated group a streptococci". Infect. Immun. 71 (1): 446–55. doi:10.1128/IAI.71.1.446-455.2003. PMC 143243. PMID 12496195.

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English Journal

Consequences of the variability of the CovRS and RopB regulators among Streptococcus pyogenes causing human infections.

Friães A1, Pato C1, Melo-Cristino J1, Ramirez M1.
Scientific reports.Sci Rep.2015 Jul 15;5:12057. doi: 10.1038/srep12057.
To evaluate the importance of covRS and ropB mutations in invasive disease caused by Group A Streptococci (GAS), we determined the sequence of the covRS and ropB genes of 191 isolates from invasive infections and pharyngitis, comprising a diverse set of emm types and multilocus sequence types. The p
PMID 26174161

HIV protease inhibitors block streptolysin S production.

Maxson T1, Deane CD1,2, Molloy EM2, Cox CL2,3, Markley AL4, Lee SW5, Mitchell DA1,2,3.
ACS chemical biology.ACS Chem Biol.2015 May 15;10(5):1217-26. doi: 10.1021/cb500843r. Epub 2015 Feb 20.
Streptolysin S (SLS) is a post-translationally modified peptide cytolysin that is produced by the human pathogen Streptococcus pyogenes. SLS belongs to a large family of azole-containing natural products that are biosynthesized via an evolutionarily conserved pathway. SLS is an important virulence f
PMID 25668590

Japanese Journal

新規に生じた心雑音により心炎の合併を同定し得た高齢発症リウマチ熱の1例

有沼良幸,菊地弘敏,荒巻芸,高山真希,浅子来未,廣畑俊成
日本臨床免疫学会会誌 = Japanese journal of clinical immunology 35(3), 194-198, 2012-06-30
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NAID 10030832745