同: SLO

WordNet

the 15th letter of the Roman alphabet (同)o
the blood group whose red cells carry neither the A nor B antigens; "people with type O blood are universal donors" (同)type_O, group O
any of several hemolysins derived from strains of streptococcus

PrepTutorEJDIC

《呼び掛けの名前の前につけて》『おお』,あ / (驚き・恐れ・喜び・苦痛などを表して)『おお』,ああ,まあ / 《肯定・否定を強めて》
oxygenの化学記号
ohmオーム / Old
osmiumの化学記号

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/02/07 22:39:59」(JST)

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Streptolysin is a streptococcal hemolytic exotoxin.^[1]^[2]

Types include streptolysin O (SLO), which is oxygen-labile, and streptolysin S (SLS), which is oxygen-stable.^[3]

An antibody, antistreptolysin O, can be detected in an antistreptolysin O titre.

Streptolysin O is hemolytically active only in a reversibly reduced state, unlike streptolysin S, which is stable in the presence of oxygen. Another difference is that that SLO is antigenic, while SLS is not antigenic due to its small size.

References

^ "streptolysin" at Dorland's Medical Dictionary
^ Streptolysin at the US National Library of Medicine Medical Subject Headings (MeSH)
^ Sierig G, Cywes C, Wessels MR, Ashbaugh CD (January 2003). "Cytotoxic effects of streptolysin o and streptolysin s enhance the virulence of poorly encapsulated group a streptococci". Infect. Immun. 71 (1): 446–55. doi:10.1128/IAI.71.1.446-455.2003. PMC 143243. PMID 12496195.

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1. A群レンサ球菌：病原性因子および発症機序 group a streptococcus virulence factors and pathogenic mechanisms
2. 急性リウマチ熱の臨床症状および診断 clinical manifestations and diagnosis of acute rheumatic fever
3. C群およびG群レンサ球菌感染症 group c and group g streptococcal infection
4. 溶連菌感染後糸球体腎炎 poststreptococcal glomerulonephritis
5. PANDAS：A群レンサ球菌が関連した小児自己免疫性神経精神疾患 pandas pediatric autoimmune neuropsychiatric disorder associated with group a streptococci

English Journal

Streptolysin-O/antibiotics adjunct therapy modulates site-specific expression of extracellular matrix and inflammatory genes in lungs of Rhodococcus equi infected foals.

Gurel V, Lambert K, Page AE, Loynachan AT, Huges K, Timoney JF, Fettinger M, Horohov DW, McMichael J.SourceBeech Tree Labs Inc, 117 Chapman St, Providence, RI, 02905, USA, Volkan_gurel@beechtreelabs.com.
Veterinary research communications.Vet Res Commun.2013 Jun;37(2):145-54. doi: 10.1007/s11259-013-9557-y. Epub 2013 Mar 9.
The addition of streptolysin-O (SLO) to the standard antibiotics regimen was shown to be superior to antibiotics alone after experimental infection of foals with Rhodoccocus equi (R. equi). The objective of this study is to investigate this response by determining the site-specific expression of ext
PMID 23475766

The imbalance of Th17/Treg in Chinese children with Henoch-Schonlein purpura.

Chen O, Zhu XB, Ren H, Wang YB, Sun R.SourceDivision of Nursing Management, Nursing School, Shandong University, #44 West Wenhua Road, Jinan 250012, China; Department of Pediatrics, Qilu Hospital, Shandong University, #107 West Wenhua Road, Jinan 250012, China; Department of Pediatrics, Second Hospital, Shandong University, #247 Beiyuan Road, Jinan 250033, China.
International immunopharmacology.Int Immunopharmacol.2013 May;16(1):67-71. doi: 10.1016/j.intimp.2013.03.027. Epub 2013 Apr 5.
Interleukin 17 (IL-17)-producing T helper (Th17) cells and CD4(+)CD25(+) regulatory T (Treg) cells are two new T-cell subsets that are thought to be critically involved in mediating and regulating autoimmune responses. The imbalance of Th17/Treg cells has been implicated in a wide range of autoimmun
PMID 23562836

Detection of miRNA in Live Cells by Using Templated RuII -Catalyzed Unmasking of a Fluorophore.

Sadhu KK, Winssinger N.SourceInstitut de Science et Ingénierie Supramoléculaires (ISIS-UMR 7006), Université de Strasbourg, CNRS, 8 allée Gaspard Monge, 67000 Strasbourg (France).
Chemistry (Weinheim an der Bergstrasse, Germany).Chemistry.2013 Apr 30. doi: 10.1002/chem.201300060. [Epub ahead of print]
Reactions templated by cellular nucleic acids are attractive for nucleic acid sensing or responsive systems. Herein we report the use of a photocatalyzed reductive cleavage of an immolative linker to unmask a rhodamine fluorophore, and its application to miRNA imaging. The reaction was found to proc
PMID 23633397

Japanese Journal

Clostridium perfringens TpeL Induces Formation of Stress Fibers via Activation of RhoA-ROCK Signaling Pathway

Nagahama Masahiro,Ohkubo Akiko,Kinouchi Yoshihito [他],Kobayashi Keiko,Miyamoto Kazuaki,Takehara Masaya,Sakurai Jun
Biological and Pharmaceutical Bulletin 38(5), 732-739, 2015
… A recombinant protein (TpeL1–525) derived from the TpeL N-terminal catalytic domain in the presence of streptolysin O (SLO) induced the formation of actin stress fibers in Madin–Darby canine kidney (MDCK) cells in a dose-dependent manner. …
NAID 130005068100

A streptolysin S homologue is essential for beta-haemolytic Streptococcus constellatus subsp constellatus cytotoxicity

Tabata A,Sato Y,Maya K,Nakano K,Kikuchi K,Whiley RA,Ohkura K,Tomoyasu T,Nagamune H
MICROBIOLOGY-SGM 160, 980-991, 2014
NAID 120005597641

Highly Sensitive and Rapid Assay of Substance P and Streptolysin O in Human Serum Using Immuno-liposomes and Gramicidin Channels

SAKAMOTO Misato,SHOJI Atsushi,SUGAWARA Masao
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 29(9), 877-883, 2013-09-10
… A highly sensitive and rapid method for the determination of substance P (SP) and streptolysin O (SLO) in human serum is described. …
NAID 10031196098

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