WordNet

any of several fat-soluble organic compounds having as a basis 17 carbon atoms in four rings; many have important physiological effects

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/09/07 17:46:11」(JST)

The steroid hydroxylases are a class of enzymes involved in the biosynthesis of steroids.

Corticosteroid biosynthetic pathway in rat

Steroid hydroxylases at the US National Library of Medicine Medical Subject Headings (MeSH)

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CYP17A1 Enzyme Activity Is Linked to Ambulatory Blood Pressure in a Family-Based Population Study.

Ackermann D1, Pruijm M2, Ponte B3, Guessous I4, Ehret G5, Escher G6, Dick B6, Al-Alwan H4, Vuistiner P4, Paccaud F4, Burnier M2, Péchère-Bertschi A7, Martin PY3, Vogt B6, Mohaupt M6, Bochud M4.
American journal of hypertension.Am J Hypertens.2016 Apr;29(4):484-93. doi: 10.1093/ajh/hpv138. Epub 2015 Aug 20.
BACKGROUND: Genome-wide association studies have linked CYP17A1 coding for the steroid hormone synthesizing enzyme 17α-hydroxylase (CYP17A1) to blood pressure (BP). We hypothesized that the genetic signal may translate into a correlation of ambulatory BP (ABP) with apparent CYP17A1 activity in a fa
PMID 26297028

Interleukin 6 increases the in vitro expression of key proteins associated with steroidogenesis in the bovine adrenal zona fasciculata.

McIlmoil S1, Strickland J1, Judd AM2.
Domestic animal endocrinology.Domest Anim Endocrinol.2016 Apr;55:11-24. doi: 10.1016/j.domaniend.2015.10.003. Epub 2015 Oct 26.
In this study, the in vitro effects of interleukin 6 (IL-6) on the messenger RNAs (mRNAs) and proteins for key steroidogenic factors in the bovine adrenal zona fasciculata (ZF) were determined. Bovine adrenal glands were obtained from an abattoir, and the ZF was isolated. Strips of ZF were then exp
PMID 26700094

Preliminary evidence of altered steroidogenesis in women with Alzheimer's disease: Have the patients "OLDER" adrenal zona reticularis?

Vaňková M1, Hill M2, Velíková M3, Včelák J4, Vacínová G5, Dvořáková K6, Lukášová P7, Vejražková D8, Rusina R9, Holmerová I10, Jarolímová E11, Vaňková H12, Kancheva R13, Bendlová B14, Stárka L15.
The Journal of steroid biochemistry and molecular biology.J Steroid Biochem Mol Biol.2016 Apr;158:157-77. doi: 10.1016/j.jsbmb.2015.12.011. Epub 2015 Dec 15.
Alzheimer's disease (AD) represents more than half of total dementias. Various factors including altered steroid biosynthesis may participate in its pathophysiology. We investigated how the circulating steroids (measured by GC-MS and RIA) may be altered in the presence of AD. Sixteen women with AD a
PMID 26704533

Extraordinarily high aldosterone, 901.0 ng/dL, in a patient with primary aldosteronism: an insight into the underlying mechanism

The combination of a novel 2 bp deletion mutation and p.D63H in <i>CYP11B1</i> cause congenital adrenal hyperplasia due to steroid 11β-hydroxylase deficiency