WordNet

any of several fat-soluble organic compounds having as a basis 17 carbon atoms in four rings; many have important physiological effects

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1. 11βヒドロキシラーゼ欠損症による先天性副腎過形成 congenital adrenal hyperplasia due to 11 beta hydroxylase deficiency
2. 副腎ステロイド生合成 adrenal steroid biosynthesis
3. 副腎不全の稀な原因 unusual causes of adrenal insufficiency
4. 内因性および外因性ステロイドの尿中排泄の測定 measurement of urinary excretion of endogenous and exogenous glucocorticoids
5. 小児における原発性副腎不全の原因および臨床症状 causes and clinical manifestations of primary adrenal insufficiency in children

Identification of seven novel CYP11B1 gene mutations in Chinese patients with 11β-hydroxylase deficiency.

Wang X1, Nie M2, Lu L3, Tong A4, Chen S5, Lu Z6.
Steroids.Steroids.2015 Aug;100:11-6. doi: 10.1016/j.steroids.2015.04.003. Epub 2015 Apr 21.
Steroid 11β-hydroxylase deficiency (11β-OHD), one of common cause of congenital adrenal hyperplasia (CAH), is an autosomal recessive disorder characterized by virilization, precocious pseudo-puberty, and hypertension. It is caused by CYP11B1 gene mutation. We performed molecular genetic analysis o
PMID 25911436

Morris DJ1.
Steroids.Steroids.2015 Jul 2;102:32-38. doi: 10.1016/j.steroids.2015.06.017. [Epub ahead of print]
The main purpose of this review article is threefold (a) to try to address the question "why are two adrenal glucocorticoids, cortisol and corticosterone, secreted by humans and other mammalian species ", (b) to outline a hypothesis that under certain physiological conditions, corticosterone has add
PMID 26144050

Schiffer L1, Anderko S1, Hannemann F1, Eiden-Plach A1, Bernhardt R2.
The Journal of steroid biochemistry and molecular biology.J Steroid Biochem Mol Biol.2015 Jul;151:38-51. doi: 10.1016/j.jsbmb.2014.10.011. Epub 2014 Oct 18.
The biosynthesis of steroid hormones is dependent on P450-catalyzed reactions. In mammals, cholesterol is the common precursor of all steroid hormones, and its conversion to pregnenolone is the initial and rate-limiting step in hormone biosynthesis in steroidogenic tissues such as gonads and adrenal
PMID 25465475