WordNet

an abnormal state in which the normal flow of a liquid (such as blood) is slowed or stopped
inactivity resulting from a static balance between opposing forces
inflammation of the skin; skin becomes itchy and may develop blisters

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皮膚炎

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/04/23 06:49:09」(JST)

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Stasis dermatitis (also known as "Congestion eczema," "Gravitational dermatitis," "Gravitational eczema," "Stasis eczema," and "Varicose eczema")^[1] refers to the skin changes that occur in the leg as a result of "stasis" or blood pooling from insufficient venous return; the alternative name of varicose eczema comes from a common cause of this being varicose veins.^{[citation needed]}

Insufficient venous return results in increased pressure in the capillaries with the result that both fluid and cells may "leak" out of the capillaries. This results in red cells breaking down, with iron containing hemosiderin possibly contributing to the pathology of this entity.^[2]

Symptoms

The skin appears thin, brown and tissue-like, with possible skin lesions (macule or patches), red spots, superficial skin irritation and/or darkening and/or thickening of the skin at the ankles or legs
The skin may be weakened and may ulcerate in areas
Legs, ankles, or other areas may become swollen
Open sores, ulcers
Itching and/or leg pains
Sometimes pain may persist from swollen tissues and may feel like "stabbing" or "needle pricks"

The cracks and poor skin-condition of this disorder predisposes for the entry of bacterial infection causing spreading cellulitis infection in the leg. If the skin condition deteriorates further and breaks down, a venous ulcer (also known as a stasis ulcer) may form.

Treatment

Treatment may consist of topical applications of steroid based creams and the use of compression stockings to help force the underlying buildup of fluids back out of the lower leg or intermittent pneumatic compression pumps.^{[medical citation needed]}

References

^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. pp. Chapter 14. ISBN 1-4160-2999-0.
^ "Stasis dermatitis and ulcers". United States National Institute of Health. Retrieved July 31, 2008.

UpToDate Contents

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1. うっ滞性皮膚炎 stasis dermatitis
2. 下肢慢性静脈疾患の内科的マネージメント medical management of lower extremity chronic venous disease
3. 下肢慢性静脈疾患の臨床症状 clinical manifestations of lower extremity chronic venous disease
4. 下肢慢性静脈疾患の概要およびマネージメント overview and management of lower extremity chronic venous disease
5. 貨幣状湿疹 nummular eczema

English Journal

All-cause and potentially disease-related health care costs associated with venous thromboembolism in commercial, medicare, and medicaid beneficiaries.

Lefebvre P, Laliberté F, Nutescu EA, Duh MS, Lamori J, Bookhart BK, Olson WH, Dea K, Schein J, Kaatz S.SourceGroupe d'analyse, Ltée, 1000 De La Gauchetière Ouest, Bureau 1200, Montréal, QC, Canada H3B 4W. plefebvre@analysisgroup.com.
Journal of managed care pharmacy : JMCP.J Manag Care Pharm.2012 Jun;18(5):363-74.
BACKGROUND: Patients with venous thromboembolism (VTE) are at increased risk of developing recurrent VTE and post-thrombotic syndrome (PTS), a complication of deep vein thrombosis (DVT) characterized by venous reflux and residual venous obstruction that may manifest as chronic pain and swelling. The
PMID 22663169

Silver sulfadiazine for the treatment of partial-thickness burns and venous stasis ulcers.

Miller AC, Rashid RM, Falzon L, Elamin EM, Zehtabchi S.SourceDepartment of Critical Care Medicine, National Institutes of Health Clinical Center, Bethesda, Maryland, USA.
Journal of the American Academy of Dermatology.J Am Acad Dermatol.2012 May;66(5):e159-65. Epub 2010 Aug 17.
BACKGROUND: For decades silver-containing antibiotics such as silver sulfadiazine (SSD) have been applied as standard topical therapy for patients with partial-thickness burns and venous stasis ulcers. This evidence-based review intends to answer the following research question: in ambulatory patien
PMID 20724028