spliceosome

出典: meddic

スプライソソームスプライソゾームスプライセオソーム

spliceosomal

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英文文献

  • Molecular identification of the dominant-negative, splicing isoform of the two-pore domain K(+) channel K2P5.1 in lymphoid cells and enhancement of its expression by splicing inhibition.
  • Endo K1, Kurokawa N2, Kito H3, Nakakura S4, Fujii M5, Ohya S6.
  • Biochemical pharmacology.Biochem Pharmacol.2015 Dec 1;98(3):440-52. doi: 10.1016/j.bcp.2015.10.002. Epub 2015 Oct 20.
  • The two-pore domain background K(+) channel K2P5.1 is expected as a possible therapeutic target for autoimmune and inflammatory disorders and cancers because it plays an important role in maintaining the resting membrane potential and regulation of Ca(2+) signaling in T lymphocytes and cancer cells.
  • PMID 26475531
  • Diverse regulation of 3' splice site usage.
  • Sohail M1, Xie J2,3.
  • Cellular and molecular life sciences : CMLS.Cell Mol Life Sci.2015 Dec;72(24):4771-93. doi: 10.1007/s00018-015-2037-5. Epub 2015 Sep 14.
  • The regulation of splice site (SS) usage is important for alternative pre-mRNA splicing and thus proper expression of protein isoforms in cells; its disruption causes diseases. In recent years, an increasing number of novel regulatory elements have been found within or nearby the 3'SS in mammalian g
  • PMID 26370726
  • Modeling of autosomal-dominant retinitis pigmentosa in Caenorhabditis elegans uncovers a nexus between global impaired functioning of certain splicing factors and cell type-specific apoptosis.
  • Rubio-Peña K1, Fontrodona L1, Aristizábal-Corrales D1, Torres S1, Cornes E1, García-Rodríguez FJ1, Serrat X1, González-Knowles D2, Foissac S3, Porta-De-La-Riva M4, Cerón J1.
  • RNA (New York, N.Y.).RNA.2015 Dec;21(12):2119-31. doi: 10.1261/rna.053397.115. Epub 2015 Oct 21.
  • Retinitis pigmentosa (RP) is a rare genetic disease that causes gradual blindness through retinal degeneration. Intriguingly, seven of the 24 genes identified as responsible for the autosomal-dominant form (adRP) are ubiquitous spliceosome components whose impairment causes disease only in the retin
  • PMID 26490224

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