WordNet
- stated explicitly or in detail; "needed a specific amount"
- a medicine that has a mitigating effect on a specific disease; "quinine is a specific for malaria"
- (sometimes followed by `to'
- being or affecting a disease produced by a particular microorganism or condition; used also of stains or dyes used in making microscope slides; "quinine is highly specific for malaria"; "a specific remedy"; "a specific stain is one having a specific affinity for particular structural elements"
- relating to or distinguishing or constituting a taxonomic species; "specific characters"
- the degree to which something is toxic to living cells
PrepTutorEJDIC
- 《名詞の前にのみ用いて》『特定の』,一定の・『明確な』,明白な・(そのものに)『特有の』,独特の《+『to』+『名』》・〈C〉(…の)特効薬《+『for』+『名』》・《複数形で》明細,細部(details)
UpToDate Contents
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English Journal
- Application of ZnO/graphene and S6 aptamers for sensitive photoelectrochemical detection of SK-BR-3 breast cancer cells based on a disposable indium tin oxide device.
- Liu F, Zhang Y, Yu J, Wang S, Ge S, Song X.SourceKey Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, PR China.
- Biosensors & bioelectronics.Biosens Bioelectron.2014 Jan 15;51C:413-420. doi: 10.1016/j.bios.2013.07.066. Epub 2013 Aug 22.
- ZnO/graphene (ZnO/G) composite and S6 aptamer were employed to sensitive photoelectrochemical (PEC) strategy for the specific detection of SK-BR-3 cancer cells based on a portable indium tin oxide microdevice. ZnO/G composite was synthesized using a facile ultrasonic method, and then applied to impr
- PMID 24007750
- Activation of complement by monoclonal antibodies that target cell-associated β2-microglobulin: Implications for cancer immunotherapy.
- Pokrass MJ, Liu MF, Lindorfer MA, Taylor RP.SourceDepartment of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, USA.
- Molecular immunology.Mol Immunol.2013 Dec 31;56(4):549-60. doi: 10.1016/j.molimm.2013.05.242. Epub 2013 Aug 1.
- β2-Microglobulin (β2M), the light chain of the class I major histocompatibilty complex (MHC-I), is a promising tumor target for monoclonal antibodies (mAbs) in cancer immunotherapy. Several reports indicate that chelation of cell-associated β2M by specific mouse mAbs promotes tumor cell destructi
- PMID 23911412
- Induction of apoptosis by high-dose gold nanoparticles in nasopharyngeal carcinoma cells.
- Lan MY, Hsu YB, Hsu CH, Ho CY, Lin JC, Lee SW.SourceDepartment of Otolaryngology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
- Auris, nasus, larynx.Auris Nasus Larynx.2013 Dec;40(6):563-8. doi: 10.1016/j.anl.2013.04.011. Epub 2013 May 27.
- OBJECTIVE: Nasopharyngeal carcinoma (NPC) is a rare malignancy in most parts of the world, but is a common cancer in southern Asia. Local recurrent disease and distant metastasis of NPC are still the unsolved problems. Recently, gold nanoparticles (AuNPs) have been developed as potential in vivo dia
- PMID 23722198
Japanese Journal
- Secure and effective gene delivery system of plasmid DNA coated by polynucleotide
- Kodama Yukinobu,Ohkubo Chikako,Kurosaki Tomoaki,Egashira Kanoko,Sato Kayoko,Fumoto Shintaro,Nishida Koyo,Higuchi Norihide,Kitahara Takashi,Nakamura Tadahiro,Sasaki Hitoshi
- Journal of Drug Targeting 23(1), 43-51, 2015-01-01
- … Polynucleotides are anionic macromolecules which are expected to transfer into the targeted cells through specific uptake mechanisms. … An inhibition study strongly indicated the specific uptake mechanism of pDNA/PEI/polyC complex. … Polynucleotide coating complexes had lower cytotoxicity than pDNA/PEI complex. …
- NAID 120005527920
- Toxicity of trichothecene mycotoxin nivalenol in human leukemia cell line HL60
- マイコトキシン 65(1), 11-17, 2015
- … NIV cytotoxicity was examined after 24 h treatment, and the inhibitor studies were performed. … That intracellular calcium ion chelator BAPTAAM mitigated the cytotoxicity of NIV indicates that this effect is dependent on intracellular calcium ion. … The results of an intracellular calcium ion modulator ryanodine receptor (RyR)1-specific inhibitor dantrolene treatment indicates that RyR1 contributes to NIV-induced toxicity. …
- NAID 130005066154
- DA-9801 Promotes Neurite Outgrowth via ERK1/2-CREB Pathway in PC12 Cells
- , , [他], , , , , ,
- Biological and Pharmaceutical Bulletin 38(2), 169-178, 2015
- … To investigate DA-9801 action, specific inhibitors targeting the ERK signaling cascade were used. … No cytotoxicity was observed in PC12 cells at DA-9801 concentrations of less than 30 µg/mL. …
- NAID 130004872243
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★リンクテーブル★
[★]
- (~に関して)明確な、はっきりとした(exact precise)、具体的な(in, about)
- (比較)(限定)特定の(particular)、一定の(⇔general)
- (~に)特有の、独特の(to)
- (比較)(医学)(~に)渡航のある(for)。特殊な
- (生物)(生物)種の
- 医学)特異の
- (物理)比の。物質固有の。単位質量・長さ・面積・容積で
n.
- 関
- specifically、specificity
[★]
- 関
- cytotoxic