テトラデシル硫酸ナトリウム
WordNet
- convert into a sulfate
- a salt or ester of sulphuric acid (同)sulphate
- a silvery soft waxy metallic element of the alkali metal group; occurs abundantly in natural compounds (especially in salt water); burns with a yellow flame and reacts violently in water; occurs in sea water and in the mineral halite (rock salt) (同)Na, atomic number 11
PrepTutorEJDIC
- ソジウム,ナトリウム(金属元素;化学記号はNa)
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/10/31 15:28:37」(JST)
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Sodium tetradecyl sulfate
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Systematic (IUPAC) name |
Sodium 7-ethyl-2-methyl-4-undecanyl sulfate
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Clinical data |
AHFS/Drugs.com |
Consumer Drug Information |
Legal status |
- Prescription only medicine
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Routes of
administration |
Intravenous injection |
Identifiers |
CAS Registry Number |
Y |
ATC code |
C05BB04 |
PubChem |
CID: 14492 |
ChemSpider |
8440 N |
UNII |
Q1SUG5KBD6 N |
ChEMBL |
CHEMBL1200354 N |
Synonyms |
7-Ethyl-2-methyl-4-hendecanol sulfate sodium salt |
Chemical data |
Formula |
C14H29NaO4S |
Molecular mass |
316.43243 g/mol |
SMILES
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CCCCC(CC)CCC(CC(C)C)OS(=O)(=O)[O-].[Na+]
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InChI
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InChI=1S/C14H30O4S.Na/c1-5-7-8-13(6-2)9-10-14(11-12(3)4)18-19(15,16)17;/h12-14H,5-11H2,1-4H3,(H,15,16,17);/q;+1/p-1 N
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Key:FVEFRICMTUKAML-UHFFFAOYSA-M N
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N (what is this?) (verify) |
Sodium tetradecyl sulfate (STS) is a commonly used synonym for 7-ethyl-2-methyl-4-undecanyl sulfate sodium salt[1] which is anionic surfactant that is the active component of the sclerosant drug Sotradecol. It is commonly used in the treatment of varicose and spider veins of the leg, during the procedure of sclerotherapy. Being a detergent, its action is on the lipid molecules in the cells of the vein wall, causing inflammatory destruction of the internal lining of the vein and thrombus formation eventually leading to sclerosis of the vein. It is used in concentrations ranging from 0.1% to 3% for this purpose. In the UK, Ireland, Italy, Australia, New Zealand and South Africa, it is sold under the trade-name Fibro-Vein in concentrations of 0.2%, 0.5%, 1.0%, and 3%.[2]
References
- ^ "SOTRADECOL® (Sodium tetradecyl sulfate)" (PDF). Retrieved 29 August 2014.
- ^ Fibro-Vein history and details
Vasoprotectives (C05)
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Antihemorrhoidals for topical use |
corticosteroids |
- Hydrocortisone
- Prednisolone
- Betamethasone
- Fluorometholone
- Fluocortolone
- Dexamethasone
- Fluocinolone acetonide
- Fluocinonide
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local anesthetics |
- Lidocaine
- Tetracaine
- Benzocaine
- Dibucaine
- Procaine
- Oxetacaine
- Pramocaine
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other |
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Antivaricose therapy |
heparins or heparinoids for topical use |
- Organo-heparinoid
- Sodium apolate
- Heparin
- Pentosan polysulfate
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sclerosing agents for local injection |
- Monoethanolamine oleate
- Polidocanol
- Inverted sugar syrup
- Sodium tetradecyl sulfate
- Phenol
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other |
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Capillary stabilising agents |
bioflavonoids |
- Rutoside
- Monoxerutin
- Diosmin
- Troxerutin
- Hidrosmin
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other |
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Index of the circulatory system
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Description |
- Anatomy
- Arteries
- head and neck
- arms
- chest
- abdomen
- legs
- Veins
- head and neck
- arms
- chest
- abdomen and pelvis
- legs
- Development
- Cells
- Physiology
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Disease |
- Congenital
- Neoplasms and cancer
- Lymphatic vessels
- Injury
- Vasculitis
- Other
- Symptoms and signs
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Treatment |
- Procedures
- Drugs
- beta blockers
- channel blockers
- diuretics
- nonsympatholytic vasodilatory antihypertensives
- peripheral vasodilators
- renin–angiotensin system
- sympatholytic antihypertensives
- vasoprotectives
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UpToDate Contents
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English Journal
- Modified Tessari Tourbillon technique for making foam sclerotherapy with silicone-free syringes.
- Whiteley MS1, Patel SB2.
- Phlebology / Venous Forum of the Royal Society of Medicine.Phlebology.2015 Oct;30(9):614-617. Epub 2014 Oct 6.
- The longevity of foam made using sodium tetradecyl sulphate and gas (air or a CO2:O2 mixture) is increased significantly if silicone-free syringes are used over the normal syringes containing silicone oil lubrication. However, the plungers in silicone-free syringes start sticking after several passa
- PMID 25288590
- Clinical outcome and predictors of treatment response in foam sodium tetradecyl sulfate sclerotherapy of venous malformations.
- Park HS1, Do YS, Park KB, Kim KH, Woo SY, Jung SH, Kim DI, Kim YW, Hyun D, Cho SK, Choo IW.
- European radiology.Eur Radiol.2015 Aug 26. [Epub ahead of print]
- OBJECTIVES: To evaluate clinical outcomes and their predictors in patients with venous malformation (VM) treated with foam sodium tetradecyl sulfate (STS) sclerotherapy.METHODS: We retrospectively evaluated clinical outcomes of foam STS sclerotherapy in 86 patients with 91 VMs to assess reduction in
- PMID 26307182
- Interaction of the Belousov-Zhabotinsky Reaction with Phospholipid Engineered Membranes.
- Torbensen K1, Rossi F2, Pantani OL3, Ristori S, Abou-Hassan A1.
- The journal of physical chemistry. B.J Phys Chem B.2015 Aug 13;119(32):10224-30. doi: 10.1021/acs.jpcb.5b04572. Epub 2015 Jul 31.
- Compartmentalized in liposome arrays, the Belousov-Zhabotinsky (BZ) oscillatory reaction might represent a good model for biochemical networks. In order to engineer such liposomes, we used small-angle X-ray scattering (SAXS) to study the effect of individual BZ reactant as well as of the entire BZ m
- PMID 26176333
Japanese Journal
- 難水溶性製剤の溶出試験に界面活性剤として使用されるラウリル硫酸ナトリウムの品質に関する研究(第1報)
- Sclerosing Therapy for Orbital Lymphangioma Using Sodium Tetradecyl Sulfate
- Poonyathalang Anuchit,Preechawat Pisit,Jiarakongmun Pakorn [他],PONGPECH Sirintara
- Japanese journal of ophthalmology 52(4), 298-304, 2008-07-01
- NAID 10021947983
- Effects of Anionic Surfactants on the Hydride-Transfer Reaction of NADH with Methylene Blue: In Premicellar and Micellar Regions
- , , ,
- Bulletin of the Chemical Society of Japan 81(2), 291-297, 2008
- … The kinetics of the hydride-transfer reaction between methylene blue (MB) and reduced nicotinamide–adenine dinucleotide (NADH) were studied in basic buffer solutions containing anionic surfactants (sodium dodecyl sulfate (SDS), sodium decyl sulfate (SDES), and sodium tetradecyl sulfate (STS)) under oxygen-saturated conditions. …
- NAID 130004058866
Related Links
- SOTRADECOL (Sodium tetradecyl sulfate) DESCRIPTION NURSING MOTHERS PEDIATRIC USE PEDIATRIC USE ADVERSE REACTIONS PREGNANCY CARCINOGENESIS, MUTAGENESIS, IMPAIRMENT OF FERTILITY
- Sodium tetradecyl sulfate is a sclerosing (skler-OH-sing) agent. It works by increasing the formation of blood clots and scar tissue inside certain types of veins. This helps decrease dilation of enlarged veins.
★リンクテーブル★
[★]
- 英
- sodium tetradecyl sulfate
[★]
- 関
- H2SO4、inorganic sulfate、sulfate ester、sulfated、sulfation、sulfuric acid、sulfuric acid ester、sulphate、sulphuric acid
[★]
- 関
- sulfate、sulfation、sulphate
[★]
スルファ、サルファ