WordNet

direct the flow of; "channel information towards a broad audience" (同)canalize, canalise
a television station and its programs; "a satellite TV channel"; "surfing through the channels"; "they offer more than one hundred channels" (同)television channel, TV channel
a passage for water (or other fluids) to flow through; "the fields were crossed with irrigation channels"; "gutters carried off the rainwater into a series of channels under the street"
(often plural) a means of communication or access; "it must go through official channels"; "lines of communication were set up between the two firms" (同)communication channel, line
a path over which electrical signals can pass; "a channel is typically what you rent from a telephone company" (同)transmission channel
a deep and relatively narrow body of water (as in a river or a harbor or a strait linking two larger bodies) that allows the best passage for vessels; "the ship went aground in the channel"
a silvery soft waxy metallic element of the alkali metal group; occurs abundantly in natural compounds (especially in salt water); burns with a yellow flame and reacts violently in water; occurs in sea water and in the mineral halite (rock salt) (同)Na, atomic number 11
(genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors" (同)cistron, factor
official routes of communication; "you have to go through channels"
informal term for information; "give me the gen on your new line of computers"

PrepTutorEJDIC

〈C〉『水路』(川・湾・運河の船の通行ができる深い部分) / 〈U〉河床・川底 / 〈C〉『海峡』 / 〈C〉みぞ(groove),(道路の)水渠(すいきょ) / 《複数形で》(運搬・伝達の)正式の経路(手続き);(一般に)経路 / 〈C〉(テレビ・ラジオの)チャンネル / …‘に'水路を開く / …‘に'みぞを堀る / …'を'伝える,流す
ソジウム,ナトリウム(金属元素;化学記号はNa)
遺伝子

UpToDate Contents

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1. 小児におけるてんかん症候群 epilepsy syndromes in children
2. 先天性および後天性ＱＴ延長症候群の遺伝学 genetics of congenital and acquired long qt syndrome
3. ドラベ症候群：遺伝学、臨床的特徴、診断 dravet syndrome genetics clinical features and diagnosis
4. ブルガダ症候群：臨床症状、診断、評価 brugada syndrome clinical presentation diagnosis and evaluation
5. ドラベ症候群：マネージメントと予後 dravet syndrome management and prognosis

English Journal

Epithelial sodium channel (ENaC) family: Phylogeny, structure-function, tissue distribution, and associated inherited diseases.

Hanukoglu I1, Hanukoglu A2.
Gene.Gene.2016 Apr 1;579(2):95-132. doi: 10.1016/j.gene.2015.12.061. Epub 2016 Jan 7.
The epithelial sodium channel (ENaC) is composed of three homologous subunits and allows the flow of Na(+) ions across high resistance epithelia, maintaining body salt and water homeostasis. ENaC dependent reabsorption of Na(+) in the kidney tubules regulates extracellular fluid (ECF) volume and blo
PMID 26772908

Overcoming super-knock down resistance (super-kdr) mediated resistance: multi-halogenated benzyl pyrethroids are more toxic to super-kdr than kdr house flies.

Sun H1,2, Tong KP1, Kasai S1,3, Scott JG1.
Insect molecular biology.Insect Mol Biol.2016 Apr;25(2):126-37. doi: 10.1111/imb.12206. Epub 2015 Dec 22.
Target site insensitivity because of mutations in the voltage-sensitive sodium channel gene (Vssc) is a major mechanism of resistance to pyrethroid insecticides in the house fly, Musca domestica. There are three known Vssc alleles that confer resistance to pyrethroids in the house fly: knock down re
PMID 26691197

Painful small fiber neuropathy with gastroparesis: A new phenotype with a novel mutation in the SCN10A gene.

Dabby R1, Sadeh M2, Broitman Y3, Yosovich K4, Dickman R3, Leshinsky-Silver E4.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia.J Clin Neurosci.2016 Apr;26:84-8. doi: 10.1016/j.jocn.2015.05.071. Epub 2015 Dec 23.
Gain-of-function mutations in the SCN10A gene (encoding the Nav1.8 voltage gated sodium channel) have been reported in a small number of patients. All presented with predominantly painful sensory neuropathy, congruent with the expression of Nav1.8 in nociceptive sensory neurons of the dorsal root ga
PMID 26711856

Japanese Journal

Becker病に特徴的な運動開始時の一過性脱力を呈したNaチャネルミオトニー

臨床神経学 57(6), 287-292, 2017
NAID 130006882276

Development of a Patient-Derived Induced Pluripotent Stem Cell Model for the Investigation of <i>SCN5A</i>-D1275N-Related Cardiac Sodium Channelopathy