関: cancer of the skin、skin cancer

WordNet

bruise, cut, or injure the skin or the surface of; "The boy skinned his knee when he fell" (同)scrape
a persons skin regarded as their life; "he tried to save his skin"
a bag serving as a container for liquids; it is made from the hide of an animal
an outer surface (usually thin); "the skin of an airplane"
a natural protective body covering and site of the sense of touch; "your skin is the largest organ of your body" (同)tegument, cutis
strip the skin off; "pare apples" (同)peel, pare
move along on skis; "We love to ski the Rockies"; "My children dont ski"
narrow wood or metal or plastic runners used in pairs for gliding over snow
a sport in which participants must travel on skis
any malignant tumor derived from epithelial tissue; one of the four major types of cancer

PrepTutorEJDIC

〈U〉〈C〉(人・動物の)『皮膚』,肌 / 〈C〉〈U〉(動物からはいだ)『皮』,『毛皮』;皮製品,皮袋 / 〈C〉(果物・野菜の)皮 / 〈U〉〈C〉(液体の表面にできる)薄い膜,上皮 / 〈C〉(枠組み・表面などを覆う)外皮,外被,外板 / 〈動物・果物など〉‘の'皮をはぐ(むく) / 〈手・脚など〉‘を'擦りむく / 《話》(金などを)〈人〉‘から'巻き上げる《+『名』〈人〉+『of』+『名』》 / 〈傷口などが〉皮で覆われる《+『over』》
『スキー』 / 『スキーで滑走する』 / …‘を'スキーで滑る / スキーの,スキー用の
(スポーツとしての)『スキー』;スキー術
がん,がん腫

UpToDate Contents

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1. Dermoscopic algorithms for skin cancer triage
2. 皮膚扁平上皮癌の治療および予後 treatment and prognosis of cutaneous squamous cell carcinoma
3. 黒色腫のスクリーニングおよび早期発見 screening and early detection of melanoma
4. 基底細胞癌の疫学および臨床的特徴 epidemiology and clinical features of basal cell carcinoma
5. 実質臓器移植受容者における皮膚癌のマネージメント management of skin cancer in solid organ transplant recipients

English Journal

Multidisciplinary management in Merkel cell carcinoma.

Matkowski R, Lata E, Zietek M, Halon A, Forgacz J, Szynglarewicz B.Author information Department of Oncology, Division of Oncological Surgery, Wroclaw Medical University , Plac Hirszfelda 12, Wroclaw , Poland.AbstractHerein, the authors describe the experience with the treatment of Merkel cell carcinoma (MCC) and review the literature regarding MCC treatment regimens. Nine patients underwent treatment due to stage I, II, or III MCC. The median follow up was 39 months. In five cases, tumors were excised with skin margins of >2 cm, and skin margins were <2 cm in four patients. Local adjuvant radiotherapy (RT) was given to four patients, while three patients underwent local lymphadenectomy (LAD). Local recurrence occurred in four patients who did not undergo RT (among them three patients had excision margins <2 cm) after a mean time of 9 months. Despite retreatment, two of those patients developed metastases. Recurrence-free survival after primary therapy was achieved: (a) in three patients with stage I and II MCC treated surgically with excision margins <2 cm combined with RT or wide excision >2 cm alone and (b) in two patients with stage III MCC treated with wide excision and LAD combined with local and regional RT. A review of the literature supports the following recommendations: (a) excision with adequate margins combined with RT; (b) LAD with regional RT in cases of lymph node involvement; and (c) sentinel lymph node biopsy in patients without clinically suspicious lymph nodes.
The Journal of dermatological treatment.J Dermatolog Treat.2014 Oct;25(5):409-14. doi: 10.3109/09546634.2012.756969. Epub 2013 Aug 13.
Herein, the authors describe the experience with the treatment of Merkel cell carcinoma (MCC) and review the literature regarding MCC treatment regimens. Nine patients underwent treatment due to stage I, II, or III MCC. The median follow up was 39 months. In five cases, tumors were excised with skin
PMID 23216365

Repair of the donor areas defects after split-thickness skin grafts utilizing an advanced epithelialization dressing.

Fanti PA, Dika E, Vaccari S, Misciali C, Ismaili A, Barisani A, Patrizi A.Author information Department of Internal Medicine, Division of Dermatology, Geriatric Diseases and Nephrology, University of Bologna , Bologna , Italy.AbstractIntroduction: The management of surgical wounds of the donor areas for split-thickness skin grafts might be difficult in terms of pain, risk of infection, and delayed healing. Materials and methods: In the period from September 2011 to June 2012, 12 patients affected by large ulcerated basal cell carcinoma (BCC) of the lower legs, 2 patients affected by squamous cell carcinoma (SCC), and 1 patient presenting malignant melanoma located on the scalp, with split-thickness skin grafts were treated. In the 12 BCC patients, the donor site areas were situated on the anterior or lateral site of the contralateral thigh and in 3 other patients on the forearms. Immediately after dermatome skin removal of 0.3 mm layer of epidermis, the donor sites were treated by applying an advanced epithelialization dressing consisting of pure cellulose film in all patients. The wound surfaces were covered by the cellulose dressing with 1 cm of excess. Bleeding was controlled with slight compression with sterile gauzes before the medication was applied. Multiple small cuts of the cellulose dressing, with a No. 11 surgical blade were made, in order to avoid hematoma formation or fluid accumulation. A mild compression bandage was used in all patients. The patients were visited after 7, 14, and 21 days. The bandage was removed after 1 week and the medical device was left at the site for other 7 days. Results: After 2 weeks, the medical device was partially detached on the underlying areas showing almost completely reepithelialization. Almost no pain was referred by the patients. In the authors' experience, this medical device markedly reduces the level of pain especially at the time of dressing application, after the surgical procedure, and during the healing process. No infections were observed. The healing process was fast and produced good aesthetic results. Conclusions: The use of Cuticell® Epigraft BSN medical device simplifies the management and healing of the donor areas for split-thickness skin grafts.
The Journal of dermatological treatment.J Dermatolog Treat.2014 Oct;25(5):434-7. doi: 10.3109/09546634.2012.757286. Epub 2013 Feb 24.
Introduction: The management of surgical wounds of the donor areas for split-thickness skin grafts might be difficult in terms of pain, risk of infection, and delayed healing. Materials and methods: In the period from September 2011 to June 2012, 12 patients affected by large ulcerated basal cell ca
PMID 23215535

Reconstruction of a large nasal defect.

Goulão J.Author information Dermatology Department, Garcia de Orta Hospital , Almada , Portugal.AbstractA 77-year-old man was referred for treatment of a biopsy-proven multirecurrence basal cell carcinoma on the dorsum of the nose. The lesion was removed and the resulting surgical defect involved the full thickness of the nasal skin leaving intact the underlying perichondrium and cartilages of the whole nasal dorsum including both sidewalls (Figure 1). The authors performed a reconstruction of a surgical defect greater than two-thirds of the nose using a single-staged bilateral Burow's wedge flap and a full-thickness skin graft from the glabella. All scars were camouflaged in the natural facial boundaries and the surgical reconstruction was performed in a single stage. The final nasal contour, symmetry and function were still good when the patient was seen 1 year after surgery.
The Journal of dermatological treatment.J Dermatolog Treat.2014 Oct;25(5):444-5. doi: 10.3109/09546634.2012.755257. Epub 2013 Feb 3.
A 77-year-old man was referred for treatment of a biopsy-proven multirecurrence basal cell carcinoma on the dorsum of the nose. The lesion was removed and the resulting surgical defect involved the full thickness of the nasal skin leaving intact the underlying perichondrium and cartilages of the who
PMID 23210844

Japanese Journal

Prevention of esophageal strictures after endoscopic submucosal dissection

Kobayashi Shinichiro,Kanai Nobuo,Ohki Takeshi,Takagi Ryo,Yamaguchi Naoyuki,Isomoto Hajime,Kasai Yoshiyuki,Hosoi Takahiro,Nakao Kazuhiko,Eguchi Susumu,Yamamoto Masakazu,Yamato Masayuki,Okano Teruo
World Journal of Gastroenterology 20(41), 15098, 2014-11-07
… Endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) have recently been accepted as less invasive methods for treating patients with early esophageal cancers such as squamous cell carcinoma and dysplasia of Barrett's esophagus. … Fabricated autologous oral mucosal epithelial cell sheets to cover the defective mucosa similarly to how commercially available skin products fabricated from epidermal cells are used for skin defects or in cases of intractable ulcers. …
NAID 120005525303

Preferential Expression of OVOL1 in Inner Root Sheath of Hair, Sebaceous Gland, Eccrine Duct and their Neoplasms in Human Skin

Mitoma Chikage,Nakahara Takeshi,Uchi Hiroshi,Ito Takamichi,Inatomi Yusuke,Ide Takatoshi,Jinnai Shunichi,Jinnai Naomi,Iwasaki Nahoko,Sakamoto Keiko,Kimura Nanae,Maeda Ayami,Kuma Yuki,Maehara Eriko,Tsutsumi Midori,Nakahara Makiko,Kido Makiko,Hirota Tomomitsu,Tamari Mayumi,Furue Masutaka
Fukuoka Acta Medica 105(8), 166-173, 2014-08-25
… Although it is known to be expressed in murine skin and hair follicles, no investigations have focused on its localization in human skin. … In the present study, we thus immunolocalized the expression of OVOL1 in normal and diseased human skin. … In normal human skin, OVOL1 was preferentially expressed in the suprabasal layer of the epidermis, inner root sheath of hair, mature sebocytes and the ductal portion of the eccrine glands. …
NAID 120005511933