skeletal muscle dihydropyridine receptor gene

骨格筋ジヒドロピリジン受容体遺伝子

WordNet

1. make ones way by force; "He muscled his way into the office"
2. animal tissue consisting predominantly of contractile cells (同)muscular_tissue
3. one of the contractile organs of the body (同)musculus
4. authority or power or force (especially when used in a coercive way); "the senators used their muscle to get the party leader to resign"
5. (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors" (同)cistron, factor
6. of or relating to or forming or attached to a skeleton; "the skeletal system"; "skeletal bones"; "skeletal muscles"
7. a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
8. informal term for information; "give me the gen on your new line of computers"

PrepTutorEJDIC

1. 〈U〉(動物体の組織としての)『筋肉』,筋(きん);〈C〉(体の各部を動かす)筋肉 / 〈U〉力,(特に)筋力,腕力 / 《俗に》(…に)強引に割り込む《+『in on』(『into, through』)+『名』》
2. 遺伝子
3. 骨格に;がい骨の;がい骨のような
4. =sense organ / 受信装置

UpToDate Contents

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• 1. 悪性高熱症の易罹患性：評価およびマネージメントsusceptibility to malignant hyperthermia evaluation and management [show details]
  …families . Genes responsible for coding proteins of the calcium channel in the sarcoplasmic reticulum are most commonly affected: the ryanodine receptor (RYR1) and the closely-associated dihydropyridine (DHP) …
• 2. 悪性高熱症：診断および急性期のマネージメントmalignant hyperthermia diagnosis and management of acute crisis [show details]
  …transverse tubule system, which activates dihydropyridine (DHP) receptors located within the t-tubule membrane These receptors are coupled to ryanodine receptors (RYR1), which regulate the passage of calcium …
• 3. 薬物熱drug fever [show details]
  …children under the age of 15 years. The primary defect is a mutation in the gene for the skeletal muscle ryanodine receptor (RyR1), which is a calcium channel found in the sarcoplasmic reticulum. The neuroleptic…
• 4. 先天性ミオパシーcongenital myopathies [show details]
  … least one mutation in this gene, muscle weakness in central core disease has been attributed to an uncoupling of excitation from calcium release . Pathogenic variants in the RYR1 gene also account for more …
• 5. 駆出率低下を伴う心不全へのカルシウム拮抗薬の使用calcium channel blockers in heart failure with reduced ejection fraction [show details]
  …addition, short-term data from the Amlodipine Exercise Trial found no benefit in parameters such as exercise tolerance, quality of life, or NYHA class . Felodipine, like amlodipine, is highly selective for vascular …

English Journal

• PMID 35039355
• PMID 34770916
• PMID 34583989

Japanese Journal

• Dysferlin and Animal Models for Dysferlinopathy

• Kobayashi Kinji,Izawa Takeshi,Kuwamura Mitsuru [他],Yamate Jyoji
• Ｊｏｕｒｎａｌ　ｏｆ　Ｔｏｘｉｃｏｌｏｇｉｃ　Ｐａｔｈｏｌｏｇｙ 25(2), 135-147, 2012
• … Dysferlin (DYSF) is involved in the membrane-repair process, in the intracellular vesicle system and in T-tubule development in skeletal muscle. … It interacts with mitsugumin 53, annexins, caveolin-3, AHNAK, affixin, S100A10, calpain-3, tubulin and dihydropyridine receptor. … gene. …
• NAID 130001884601

• トランスポゾンランダム挿入法を用いた蛍光性RyR1チャネルの作製

• 村山 尚,樫山 拓,呉林 なごみ,小林 琢也,小山田 英人,小口 勝司,櫻井 隆
• 日本生理学会大会発表要旨集 2008(0), 074-074, 2008
• … Type 1 ryanodine receptor (RyR1) is a large intracellular Ca<SUP>2+</SUP> … release channels in the sarcoplasmic reticulum of skeletal muscle and plays an essential role in excitation-contraction coupling. … Although the RyR1 channel is believed to be opened via some physical interaction with dihydropyridine receptor of the T-tubule, the detailed mechanism remains still unclear. …
• NAID 130005449465

Related Links

• Dihydropyridine receptor gene expression in skeletal muscle ...

Dihydropyridine receptor gene expression in skeletal muscle from mdx and control mice Author links open overlay panel Yann Péréon a Christine Dettbarn a Javier Navarro a Jacques Noireaud b Philip T Palade a Show more Share ...

• Dihydropyridine receptor gene expression in skeletal muscle ...

T1 - Dihydropyridine receptor gene expression in skeletal muscle from mdx and control mice AU - Péréon, Yann AU - Dettbarn, Christine AU - Navarro, Javier AU - Noireaud, Jacques AU - Palade, Philip T.

• Regulation of dihydropyridine receptor gene expression in ...

This study examined dihydropyridine receptor (DHPR) gene expression in mouse skeletal muscles during physiological adaptations to disuse. Disuse was produced by three in vivo models-denervation, tenotomy, and immobilization-and DHPR alpha1s mRNA was measured by quantitative Northern blot.

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★リンクテーブル★

リンク元	「骨格筋ジヒドロピリジン受容体遺伝子」
関連記事	「skeletal」「receptor gene」「skeletal muscle」「dihydropyridine」「muscle」

「骨格筋ジヒドロピリジン受容体遺伝子」

　　[★]

英

skeletal muscle dihydropyridine receptor gene

関

骨格筋ジヒドロピリジン受容体、骨格筋、ジヒドロピリジン、ジヒドロピリジン受容体

「skeletal」

　　[★]

• adj.

• 骨格の、骸骨の(ような)

関

scaffold, skeleton

　 　

「receptor gene」

　　[★]

• 受容体遺伝子、レセプター遺伝子

「skeletal muscle」

　　[★]

関

See also Muscle; Muscle contraction

「dihydropyridine」

　　[★] ジヒドロピリジン DHP

「muscle」

　　[★]

• n.

• 筋肉