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  • Determination of equilibrium constant of amino carbamate adduct formation in sisomicin by a high pH based high performance liquid chromatography.
  • Wlasichuk KB1, Tan L2, Guo Y1, Hildebrandt DJ1, Zhang H1, Karr DE1, Schmidt DE Jr3.
  • Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2015 Jul 10;111:126-30. doi: 10.1016/j.jpba.2015.03.033. Epub 2015 Apr 3.
  • Amino carbamate adduct formation from the amino group of an aminoglycoside and carbon dioxide has been postulated as a mechanism for reducing nephrotoxicity in the aminoglycoside class compounds. In this study, sisomicin was used as a model compound for amino carbamate analysis. A high pH based reve
  • PMID 25880243
  • Designer aminoglycosides prevent cochlear hair cell loss and hearing loss.
  • Huth ME, Han KH, Sotoudeh K, Hsieh YJ, Effertz T, Vu AA, Verhoeven S, Hsieh MH, Greenhouse R, Cheng AG, Ricci AJ.
  • The Journal of clinical investigation.J Clin Invest.2015 Feb;125(2):583-92. doi: 10.1172/JCI77424. Epub 2015 Jan 2.
  • Bacterial infections represent a rapidly growing challenge to human health. Aminoglycosides are widely used broad-spectrum antibiotics, but they inflict permanent hearing loss in up to ~50% of patients by causing selective sensory hair cell loss. Here, we hypothesized that reducing aminoglycoside en
  • PMID 25555219
  • Microbiological spectrum and susceptibility pattern of clinical isolates from the neonatal unit in a single medical center.
  • Nitsch-Osuch A1, Choroszy-Król I2, Kuchar E3, Korzeniewski K4, Życińska K1, Wardyn K1.
  • Advances in clinical and experimental medicine : official organ Wroclaw Medical University.Adv Clin Exp Med.2015 Jan-Feb;24(1):15-22. doi: 10.17219/acem/38170.
  • BACKGROUND: Infections are a frequent and significant cause of morbidity and mortality in neonatal units. The bacterial pathogens and their susceptibility patterns should be monitored in hospital settings. The aim of the study was to describe the distribution of the bacterial agents and their antibi
  • PMID 25923082


  • Identification of gntK, a gene required for the methylation of purpurosamine C-6′ in gentamicin biosynthesis
  • The Journal of General and Applied Microbiology 58(5), 349-356, 2012
  • NAID 130004449342
  • Development of a non-derivatization high-performance liquid chromatography method with resonance Rayleigh scattering detection for the detection of sisomicin in rat serum
  • Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 877(31), 4022-4026, 2009-12-01
  • NAID 10028029661
  • Simple and sensitive method for quantification of low tobramycin concentrations in human plasma using HPLC-MS/MS
  • Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 862(1), 257-262, 2008-02-01
  • NAID 10024543203


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sisomicin, sissomicin an aminoglycoside antibiotic similar to gentamicin produced by cultures of Micromonospora inyoensis. Used as the sulfate. ... Disclaimer All content on this website, including dictionary, thesaurus, literature ...



拡張検索sisomicin sulfate



硫酸シソマイシン sisomicin sulfate

sisomicin sulfate」