WordNet
- any of various water-soluble compounds capable of turning litmus blue and reacting with an acid to form a salt and water; "bases include oxides and hydroxides of metals and ammonia" (同)alkali
- (numeration system) the positive integer that is equivalent to one in the next higher counting place; "10 is the radix of the decimal system" (同)radix
- the bottom side of a geometric figure from which the altitude can be constructed; "the base of the triangle"
- situate as a center of operations; "we will base this project in the new lab"
- a place that the runner must touch before scoring; "he scrambled to get back to the bag" (同)bag
- installation from which a military force initiates operations; "the attack wiped out our forward bases" (同)base of operations
- a support or foundation; "the base of the lamp" (同)pedestal, stand
- (electronics) the part of a transistor that separates the emitter from the collector
- a flat bottom on which something is intended to sit; "a tub should sit on its own base"
- the principal ingredient of a mixture; "glycerinated gelatin is used as a base for many ointments"; "he told the painter that he wanted a yellow base with just a hint of green"; "everything she cooked seemed to have rice as the base"
- the place where you are stationed and from which missions start and end (同)home
- (anatomy) the part of an organ nearest its point of attachment; "the base of the skull"
- the bottom or lowest part; "the base of the mountain"
- illegitimate (同)baseborn
- of low birth or station (`base is archaic in this sense); "baseborn wretches with dirty faces"; "of humble (or lowly) birth" (同)baseborn, humble, lowly
- not adhering to ethical or moral principles; "base and unpatriotic motives"; "a base, degrading way of life"; "cheating is dishonorable"; "they considered colonialism immoral"; "unethical practices in handling public funds" (同)immoral
- having or showing an ignoble lack of honor or morality; "that liberal obedience without which your army would be a base rabble"- Edmund Burke; "taking a mean advantage"; "chokd with ambition of the meaner sort"- Shakespeare; "something essentially vulgar and meanspirited in politics" (同)mean, meanspirited
- (used of metals) consisting of or alloyed with inferior metal; "base coins of aluminum"; "a base metal"
- debased; not genuine; "an attempt to eliminate the base coinage"
- used of flowers having usually only one row or whorl of petals; "single chrysanthemums resemble daisies and may have more than one row of petals"
- a base hit on which the batter stops safely at first base (同)bingle
- not divided among or brought to bear on more than one object or objective; "judging a contest with a single eye"; "a single devotion to duty"; "undivided affection"; "gained their exclusive attention" (同)undivided, exclusive
- existing alone or consisting of one entity or part or aspect or individual; "upon the hill stood a single tower"; "had but a single thought which was to escape"; "a single survivor"; "a single serving"; "a single lens"; "a single thickness"
- having uniform application; "a single legal code for all"
- hit a single; "the batter singled to left field"
- to make melodious sounds; "The nightingale was singing"
- deliver by singing; "Sing Christmas carols"
- produce tones with the voice; "She was singing while she was cooking"; "My brother sings very well"
- the act of putting one thing or person in the place of another: "he sent Smith in for Jones but the substitution came too late to help" (同)exchange, commutation
- an event in which one thing is substituted for another; "the replacement of lost blood by a transfusion of donor blood" (同)permutation, transposition, replacement, switch
- having a base; "firmly based ice"
- having a base of operations (often used as a combining form); "a locally based business"; "an Atlanta-based company"; "carrier-based planes"
PrepTutorEJDIC
- 《文》(人や人の行動・孝えが)『卑しい』,下劣な / (金属が)質の劣った;(貨幣が)粗悪な
- 『基礎』,根拠 / 『基部』,基底,土台 / 『根拠地』,基地 / (野球の)塁,ベース / 主成分;塩基(酸と反応シテ塩(官)を生じる化合物) / (数学で図形の)底;底辺;基線 / (…に)…‘の'『基礎をおく』《+『名』+『on』(『upon』)+『名』》
- 《名詞の前にのみ用いて》『たった一つ』(『一人』)『の』,単独の;《否定文で》ただ一つ(一人)(もない) / 《名詞の前にのみ用いて》『一人用の』・『独身の』・《名詞の前にのみ用いて》個々の,別々の / 単一の,単式の;(花が)一重咲きの,単弁の / 《英》(切符が)片道の / 〈C〉一人,1個;独身者 / 〈C〉《話》(ホテルの部屋,船室,列車寝台などの)一人用 / 〈C〉(野球で)シングルヒット,単打 / 《複数形で》(テニスなどの)シングルスの試合,単試合 / 《英》片道切符 / 《複数形で》《話》1ドル(ポンド)札 / …‘を'1人(1個)だけ選び出す《+『out』+『名,』+『名』+『out』》 / (野球で)シングルヒットを打つ
- 『歌う』;(…に)歌って聞かせる《+『to』(『for』)+『名』》;(楽器に合わせて)歌う《+『to』+『名』》・〈小鳥・虫などが〉『鳴く』,さえずる / 《文》(…を)詩(歌)にする,(詩(歌)を詠んで)賛美する《+『of』+『名』》・〈小川・風・弾丸・湯沸かし・耳などが〉歌うように鳴る・《米語》自白する;密告する・〈歌〉‘を'歌う・《副詞[句]を伴って》歌って…‘を'(…に)する・…‘を'唱える,詠唱する・《文》…‘を'詩(歌)にする,(詩(歌)に詠んで)賛美する・合唱の集い
- (…の)『代用』,代理,置き換え《+for+名》
UpToDate Contents
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- 1. 臍帯血酸塩基分析 umbilical cord blood acid base analysis
- 2. 遺伝性疾患の基本原則 basic principles of genetic disease
- 3. 胎児の酸塩基の生理学 fetal acid base physiology
- 4. 単純性および混合性酸塩基障害 simple and mixed acid base disorders
- 5. 妊娠時のブプレノルフィン補充療法 buprenorphine substitution therapy in pregnancy
English Journal
- Entropy Beacon: A Hairpin-Free DNA Amplification Strategy for Efficient Detection of Nucleic Acids.
- Lv Y1, Cui L1, Peng R1, Zhao Z1, Qiu L2, Chen H1, Jin C1, Zhang XB1, Tan W1,2.
- Analytical chemistry.Anal Chem.2015 Dec 1;87(23):11714-20. doi: 10.1021/acs.analchem.5b02654. Epub 2015 Nov 17.
- Here, we propose an efficient strategy for enzyme- and hairpin-free nucleic acid detection called an entropy beacon (abbreviated as Ebeacon). Different from previously reported DNA hybridization/displacement-based strategies, Ebeacon is driven forward by increases in the entropy of the system, inste
- PMID 26505212
- Transition State Charge Stabilization and Acid-Base Catalysis of mRNA Cleavage by the Endoribonuclease RelE.
- Dunican BF1, Hiller DA1, Strobel SA1.
- Biochemistry.Biochemistry.2015 Dec 1;54(47):7048-57. doi: 10.1021/acs.biochem.5b00866. Epub 2015 Nov 12.
- The bacterial toxin RelE is a ribosome-dependent endoribonuclease. It is part of a type II toxin-antitoxin system that contributes to antibiotic resistance and biofilm formation. During amino acid starvation, RelE cleaves mRNA in the ribosomal A-site, globally inhibiting protein translation. RelE is
- PMID 26535789
- Variant c.2262A>C in DOCK9 Leads to Exon Skipping in Keratoconus Family.
- Karolak JA1, Rydzanicz M2, Ginter-Matuszewska B1, Pitarque JA3, Molinari A3, Bejjani BA4, Gajecka M1.
- Investigative ophthalmology & visual science.Invest Ophthalmol Vis Sci.2015 Dec 1;56(13):7687-7690. doi: 10.1167/iovs.15-17538.
- Purpose: Keratoconus (KTCN) is a degenerative disorder of the eye that is characterized by a conical shape and thinning of the cornea, resulting in impaired visual function. Previously, we identified heterozygous single base-pair substitutions in DOCK9, IPO5, and STK24, showing concurrent 100% segre
- PMID 26641546
Japanese Journal
- 頸部血管の異常蛇行と脳皮質下出血を示したMarfan症候群：FBN1遺伝子イントロン変異をみとめた症例
- 音成 秀一郎,竹島 慎一,姫野 隆洋,吉本 武史,高松 和弘,森崎 裕子,栗山 勝
- 臨床神経学 54(11), 897-902, 2014
- 症例は39歳男性である．Marfan症候群と診断され，22歳で大動脈拡張と心臓弁の手術後，ワルファリン内服中に，左前頭葉皮質下出血で入院した．頭部画像検査で，皮質下出血の原因となる異常血管はみとめず，多発微小出血および異常に蛇行した頸部血管をみとめた．遺伝子解析ではフィブリリン1（FBN1）遺伝子解析で第29イントロン部-3位に1塩基置換変異をみとめた．同変異は両親にはみとめず，Marfan症候群 …
- NAID 130004706048
- 痙攣と精神運動遅滞を主訴としたhypoxanthine-guanine phosphoribosyltransferase部分欠損症の1例
- 吉本 武史,姫野 隆洋,竹島 慎一,音成 秀一郎,山田 憲一郎,山田 裕一,栗山 勝
- 臨床神経学 54(11), 892-896, 2014
- 症例は18歳の男性である．幼少時より知的障害，12歳で注意欠陥・多動性障害を指摘され，18歳で痙攣をきたした．精神遅滞，腱反射亢進をみとめるが，不随意運動，自傷行為はない．高尿酸血症があり，赤血球hypoxanthine-guanine phosphribosyltransferase（HPRT）の部分低下（残存活性57.4％）をみとめ，HPRT遺伝子解析では，第3エクソンで，1塩基置換（c.17 …
- NAID 130004706047
- Comparative Studies of Human UDP-glucuronosyltransferase 1A8 and 1A9 Proximal Promoters Using Single Base Substitutions
- XIAO Zhang,NUNOME Kana,YAHARA Taemi,INOUE Emi,NABESHIMA Masakazu,TSUCHIDA Shirou,HAMAUE Naoya,AOKI Takashi
- Drug Metabolism and Pharmacokinetics 29(1), 90-93, 2014
- … In extra-hepatic cells, Caco2, the activity of UGT1A9 proximal promoter increased to 73.4 ± 8.5% of that of the UGT1A8 proximal promoter with only 4 base changes: −160C, −152A, −62T, and −59G. … Therefore, the cause of the low activity of the UGT1A9 proximal promoter may be not only 4 base changes, but also the truncation of T repeats. …
- NAID 130004463340
Related Links
- Possible involvement in oncogenesis of a single base mutation in an internal ribosome entry site of Epstein,Barr nuclear antigen 1 mRNA JOURNAL OF MEDICAL VIROLOGY, Issue 4 2004 Rika Endo Abstract It has been reported ...
- Indole in DNA: Comparison of a Nucleosidic with a Non-Nucleosidic DNA Base Substitution EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 3 2009 Janez Barbaric Abstract The synthetic incorporation of indole as an ...
Related Pictures
★リンクテーブル★
| リンク元 | 「一塩基置換」「single nucleotide substitution」 |
| 関連記事 | 「base」「single」「sing」「single base」 |
「一塩基置換」
「single nucleotide substitution」
「base」
- n.
- 関
- basal、base、basement、basic、basis、element、elementary、evidence、foundation、fundamental、fundamentals、fundus、ground、infrastructure、reason
「single」
- adj.
- 単一の、一回の、単、(薬物投与)単回の
- n.
- 個人、選抜する
「sing」
- v.
- 過去sang-過去分詞sung