サル出血熱ウイルス

関: Arteriviridae、arterivirus

WordNet

a harmful or corrupting agency; "bigotry is a virus that must not be allowed to spread"; "the virus of jealousy is latent in everyone"
(virology) ultramicroscopic infectious agent that replicates itself only within cells of living hosts; many are pathogenic; a piece of nucleic acid (DNA or RNA) wrapped in a thin coat of protein
a software program capable of reproducing itself and usually capable of causing great harm to files or other programs on the same computer; "a true virus cannot spread to another computer without human assistance" (同)computer virus
a rise in the temperature of the body; frequently a symptom of infection (同)febrility, febricity, pyrexia, feverishness
intense nervous anticipation; "in a fever of resentment"
highly excited; "a fevered imagination"
relating to or resembling an ape; "simian features"
an ape or monkey
of or relating to a hemorrhage (同)haemorrhagic

PrepTutorEJDIC

ビールス,ろ過性病原体
〈U〉《しばしばa fever》(身体の異常な)『熱』,発熱 / 〈U〉『熱病』 / 〈U〉〈C〉(…に対する)『興奮』,熱狂《+『for』+『名』》
(比較変化なし)《名詞の前にのみ用いて》熱のある,熱病にかかった / 熱にうかされたような,興奮した / (憎しみなどが)異常に強い
類人猿の,猿のような / 類人猿,猿

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/09/18 00:31:13」(JST)

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[Wiki en表示]

Simian hemorrhagic fever virus or simian haemorrhagic fever virus or SHFV is a highly pathogenic virus in monkeys. It is a positive-stranded RNA virus classified in the family Arteriviridae.

Hosts

Patas are believed to be the natural host for the virus since about 50% of wild patas monkeys have antibodies for the virus, while antibodies are much less prevalent in other simian species such as vervets and baboons. In macaques, however, infection with this virus can result in acute severe disease with high mortality. Recently, red colobus monkeys and red-tailed guenons have been identified as natural hosts for SHFV.^[1]^[2]

Symptoms

Asymptomatic infection of the virus can occur in patas monkeys, vervet monkeys, and baboons, although it is observed primarily in patas monkeys. Infection has a rapid onset with animals developing a high fever, facial edema, cyanosis, anorexia, melena, and may begin to hemorrhage at the cutaneous, subcutaneous, and retrobulbar levels. Thrombocytopenia will develop soon after. Death usually occurs within 10–15 days after symptoms appear.^[3]

References

^ Lauck M, Hyeroba D, Tumukunde A, Weny G, Lank SM, et al. (2011) Novel, Divergent Simian Hemorrhagic Fever Viruses in a Wild Ugandan Red Colobus Monkey Discovered Using Direct Pyrosequencing. PLoS ONE 6(4): e19056. doi:10.1371/journal.pone.0019056
^ Lauck M, Sibley SD, Hyeroba D, Tumukunde A, Weny G, Chapman CA, Ting N, Switzer WM, Kuhn JH, Friedrich TC, O'Connor DH, Goldberg TL. (2013) Exceptional simian hemorrhagic fever virus diversity in a wild African primate community. Journal of Virology 87(1):688-91. http://www.ncbi.nlm.nih.gov/pubmed/23077302
^ Richard L. Walker, Dwight C. Hirsh, Nigel James. "Vet. Biology" Blackwell Publishing, 2004.

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English Journal

DDX19A Senses Viral RNA and Mediates NLRP3-Dependent Inflammasome Activation.

Li J1, Hu L1, Liu Y1, Huang L1, Mu Y2, Cai X1, Weng C3.
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The NLRP3 inflammasome plays a major role in innate immune responses by activating caspase-1, resulting in secretion of IL-1β and inflammatory pathologic responses. Viral RNA can induce NLRP3 inflammasome activation. However, none of the components of NLRP3 inflammasome has the ability to bind vira
PMID 26538395

Novel highly specific anti-periostin antibodies uncover the functional importance of the fascilin 1-1 domain and highlight preferential expression of periostin in aggressive breast cancer.

Field S1,2, Uyttenhove C3,4, Stroobant V3, Cheou P4, Donckers D4, Coutelier JP4, Simpson PT5,6,7, Cummings MC5,8,7, Saunus JM5,6, Reid LE5,6, Kutasovic JR5,6, McNicol AM5,7, Kim BR9,10, Kim JH9,10,11, Lakhani SR5,8,7, Neville AM12, Van Snick J3,4, Jat PS2,13.
International journal of cancer. Journal international du cancer.Int J Cancer.2015 Dec 1. doi: 10.1002/ijc.29946. [Epub ahead of print]
Periostin (POSTN), a secreted homodimeric protein that binds integrins αvβ3, αvβ5 and α6β4, was originally found to be expressed in fetal tissues and in the adult upon injury particularly bone fractures due to its role in remodelling and repair. Recently it was found to be over-expressed in hu
PMID 26619948

The nonstructural protein 11 of porcine reproductive and respiratory syndrome virus inhibits NF-κB signaling by means of its deubiquitinating activity.

Wang D1, Fan J1, Fang L1, Luo R1, Ouyang H1, Ouyang C1, Zhang H1, Chen H1, Li K2, Xiao S3.
Molecular immunology.Mol Immunol.2015 Dec;68(2 Pt A):357-66. doi: 10.1016/j.molimm.2015.08.011. Epub 2015 Sep 3.
Since its emergence in the late 1980s, porcine reproductive and respiratory syndrome (PRRS) has been devastating the swine industry worldwide. The causative agent is an Arterivirus, referred to as PRRS virus (PRRSV). The pathogenic mechanisms of PRRS are poorly understood, but are believed to correl
PMID 26342881

Japanese Journal

Lelystad virus belongs to a new virus family, comprising lactate dehydrogenase-elevating virus, equine arteritis virus, and simian hemorrhagic fever virus.

Arch. Virol. 9, 441-448, 1994
NAID 10005162104

「Arteriviridae」

Simian hemorrhagic fever virus
Virus classification
Group:	Group IV ((+)ssRNA)
Order:	Nidovirales
Family:	Arteriviridae
Genus:	Arterivirus
Species:	Simian hemorrhagic fever virus

　　[★]

アルテリウイルス科

ルテリウイルス科

関: arterivirus、simian hemorrhagic fever virus

「サル出血熱ウイルス」

　　[★]

英: simian hemorrhagic fever virus
関: アルテリウイルス、アルテリウイルス科

「arterivirus」

　　[★]

アルテリウイルス

関: Arteriviridae、simian hemorrhagic fever virus

「hemorrhagic」

　　[★]

adj.

出血性の、易出血性の

関: haemophilic、haemorrhagic、hemophilic

「simian」

　　[★]

サルの

関: monkey

「hemorrhagic fever」

　　[★] 出血熱

関: haemorrhagic fever

「virus」

　　[★] ウイルス

[1] Lauck M, Hyeroba D, Tumukunde A, Weny G, Lank SM, et al. (2011) Novel, Divergent Simian Hemorrhagic Fever Viruses in a Wild Ugandan Red Colobus Monkey Discovered Using Direct Pyrosequencing. PLoS ONE 6(4): e19056. doi:10.1371/journal.pone.0019056

[2] Lauck M, Sibley SD, Hyeroba D, Tumukunde A, Weny G, Chapman CA, Ting N, Switzer WM, Kuhn JH, Friedrich TC, O'Connor DH, Goldberg TL. (2013) Exceptional simian hemorrhagic fever virus diversity in a wild African primate community. Journal of Virology 87(1):688-91. http://www.ncbi.nlm.nih.gov/pubmed/23077302

[3] Richard L. Walker, Dwight C. Hirsh, Nigel James. "Vet. Biology" Blackwell Publishing, 2004.

リンク元	「Arteriviridae」「サル出血熱ウイルス」「arterivirus」
関連記事	「hemorrhagic」「simian」「hemorrhagic fever」「virus」

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案内

案内

simian hemorrhagic fever virus