WordNet

any of several plant glycoproteins that act like specific antibodies but are not antibodies in that they are not evoked by an antigenic stimulus

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Overlapping and unique signatures in the proteomic and transcriptomic responses of the nematode Caenorhabditis elegans toward pathogenic Bacillus thuringiensis.

Yang W1, Dierking K1, Esser D2, Tholey A3, Leippe M4, Rosenstiel P2, Schulenburg H5.
Developmental and comparative immunology.Dev Comp Immunol.2015 Jul;51(1):1-9. doi: 10.1016/j.dci.2015.02.010. Epub 2015 Feb 23.
Pathogen infection can activate multiple signaling cascades that ultimately alter the abundance of molecules in cells. This change can be measured both at the transcript and protein level. Studies analyzing the immune response at both levels are, however, rare. Here, we compare transcriptome and pro
PMID 25720978

REG3A accelerates pancreatic cancer cell growth under IL-6-associated inflammatory condition: Involvement of a REG3A-JAK2/STAT3 positive feedback loop.

Liu X1, Wang J2, Wang H3, Yin G1, Liu Y4, Lei X4, Xiang M5.
Cancer letters.Cancer Lett.2015 Jun 28;362(1):45-60. doi: 10.1016/j.canlet.2015.03.014. Epub 2015 Mar 14.
Regenerating gene protein (REG) 3A is a 19 kD secretory pancreas protein with pro-growth function. Previously we demonstrated that overexpression of REG3A, acting as a key molecule for up-regulation of the JAK2/STAT3 pathway, contributed to inflammation-related pancreatic cancer (PaC) development. H
PMID 25779676

Nabi IR1, Shankar J2, Dennis JW3.
Journal of cell science.J Cell Sci.2015 Jun 19. pii: jcs.151159. [Epub ahead of print]
Galectins are a family of widely expressed β-galactoside-binding lectins in metazoans. The 15 mammalian galectins have either one or two conserved carbohydrate recognition domains (CRDs), with galectin-3 being able to pentamerize; they form complexes that crosslink glycosylated ligands to form a dy
PMID 26092931

Gabius Hans-Joachim
Trends in glycoscience and glycotechnology 23(132), 168-177, 2011-11-30
… They are translated into biological responses by first binding to lectins, this recognition process thereupon triggering ensuing post-binding signaling. … This review dissects the different ways Ca2+ functions as an integral component of various lectins' carbohydrate-binding domains. …
NAID 10030388716

Extra- and intracellular signaling pathways regulating nodule formation by hemocytes of the silkworm, Bombyx mori(Lepidoptera: Bombicidae)

Suzuki Asahi,Yoshizawa Yasutaka,Tanaka Shiho,Kitami Madoka,Sato Ryoichi
Journal of Insect Biotechnology and Sericology 80(2), 2_049-2_056, 2011
… It has been suggested that early defense mechanisms of the silkworm Bombyx mori, which can clear 106 bacterial cells from the hemolymph within 30minutes, largely depend on pathogen recognition mediated by dual-carbohydrate recognition domain (CRD) C-type lectins and nodule formation by hemocytes. … These results suggested that dual-CRD C-type lectins were required as pathogen-recognition receptors for nodule formation. …
NAID 130004464180

Intracellular Lectins Involved in Folding and Transport in the Endoplasmic Reticulum

Yamamoto Kazuo
Biological and Pharmaceutical Bulletin 32(5), 767-773, 2009
… The first is the role of glycosylation in the extracellular environment, where a variety of sugar chains participate in protein secretion and stability, cell–cell adhesion and signaling, innate immunity, embryogenesis, and morphogenesis. … Here, I focus on the intracellular lectins that participate in these processes and discuss the role of glycosylation based on the structural differences of N-glycans. …
NAID 130000117136