シッカニン、シツカニン
English Journal
- Inhibitory effects of respiration inhibitors on aflatoxin production.
- Sakuda S1, Prabowo DF2, Takagi K3, Shiomi K4, Mori M4, Ōmura S5, Nagasawa H6.
- Toxins.Toxins (Basel).2014 Mar 26;6(4):1193-200. doi: 10.3390/toxins6041193.
- Aflatoxin production inhibitors, which do not inhibit the growth of aflatoxigenic fungi, may be used to control aflatoxin without incurring a rapid spread of resistant strains. A respiration inhibitor that inhibits aflatoxin production was identified during a screening process for natural, aflatoxin
- PMID 24674936
- Screening for microbial metabolites affecting phenotype of Caenorhabditis elegans.
- Yamamuro D1, Uchida R, Takahashi Y, Masuma R, Tomoda H.
- Biological & pharmaceutical bulletin.Biol Pharm Bull.2011;34(10):1619-23.
- Microbial samples, including our library of known microbial compounds (ca. 300) and microbial culture broths (ca. 9000), were screened for small molecules affecting the phenotype of Caenorhabditis elegans. As a result, seven known compounds were found to induce phenotypic abnormality of C. elegans.
- PMID 21963505
- Siccanin rediscovered as a species-selective succinate dehydrogenase inhibitor.
- Mogi T1, Kawakami T, Arai H, Igarashi Y, Matsushita K, Mori M, Shiomi K, Omura S, Harada S, Kita K.
- Journal of biochemistry.J Biochem.2009 Sep;146(3):383-7. doi: 10.1093/jb/mvp085. Epub 2009 Jun 8.
- To identify antibiotics targeting to respiratory enzymes, we carried out matrix screening of a structurally varied natural compound library with Pseudomonas aeruginosa membrane-bound respiratory enzymes. We identified a succinate dehydrogenase inhibitor, siccanin (IC(50), 0.9 microM), which is a pot
- PMID 19505951
Japanese Journal
- Screening for Microbial Metabolites Affecting Phenotype of Caenorhabditis elegans
- Yamamuro Daisuke,Uchida Ryuji,Takahashi Yoko [他],Masuma Rokuro,Tomoda Hiroshi
- Biological and Pharmaceutical Bulletin 34(10), 1619-1623, 2011
- … elegans, avermectin B1a exhibited hatching inhibition of starting eggs on day 1 at 25—100 μM and growth inhibition at 0.01—12.5 μM, siccanin and antimycin A inhibited the growth of C. …
- NAID 130001086597
- Siccanin Rediscovered as a Species-Selective Succinate Dehydrogenase Inhibitor
- Mogi Tatsushi,Kawakami Takuro,Arai Hiroyuki [他],IGARASHI Yasuo,MATSUSHITA Kazunobu,MORI Mihoko,SHIOMI Kazuro,OMURA Satoshi,HARADA Shigeharu,KITA Kiyoshi
- The journal of biochemistry 146(3), 383-387, 2009-09-01
- NAID 10026303339
- Effects of Antifungal Drugs on Proliferation Signals in Candida albicans(Microbiology)
- Matsuki Mitsuo,Kanatsu Hatsuki,Watanabe Toshihiko [他],OGASAWARA Ayako,MIKAMI Takeshi,MATSUMOTO Tatsuji
- Biological & pharmaceutical bulletin 29(5), 919-922, 2006-05-01
- … Ciclopirox olamine and siccanin were more effective under aerobic than under anaerobic conditions. …
- NAID 110005602214
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