WordNet

make saw-toothed or jag the edge of; "serrate the edges of the teeth"
notched like a saw with teeth pointing toward the apex (同)serrated, saw-toothed, toothed, notched
a benign epithelial tumor of glandular origin

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1. 大腸ポリープ患者に対するアプローチ approach to the patient with colonic polyps
2. 大腸癌の分子遺伝学 molecular genetics of colorectal cancer
3. 大腸癌：疫学、危険因子、および防御因子 colorectal cancer epidemiology risk factors and protective factors

Traditional serrated adenoma of the colorectum: clinicopathologic implications and endoscopic findings of the precursor lesions.

Kim MJ, Lee EJ, Suh JP, Chun SM, Jang SJ, Kim do S, Lee DH, Lee SH, Youk EG.SourceDept of Pathology, Daehang Hospital, 481-10 BangBae3-dong, Seocho-gu, 137-820, Seoul, South Korea; mjkimdoc@gmail.com.
American journal of clinical pathology.Am J Clin Pathol.2013 Dec;140(6):898-911. doi: 10.1309/AJCPDJC9VC5KTYUS.
Objectives: To investigate the clinicopathologic and endoscopic features of precursor lesions associated with traditional serrated adenomas (TSAs). Methods: Mutation studies for BRAF, KRAS, PIK3CA, and EGFR and immunohistochemical staining for Ki-67 were performed on 107 TSAs from 104 patients. Resu
PMID 24225759

Bhalla A, Zulfiqar M, Weindel M, Shidham VB.SourcePathology Department, Harper University Hospital, Detroit Medical Center, Wayne State University School of Medicine, 3990 John R Street, Detroit, MI 48201, USA.
Clinics in laboratory medicine.Clin Lab Med.2013 Dec;33(4):835-59. doi: 10.1016/j.cll.2013.10.001.
Molecular pathogenesis and classification of colorectal carcinoma are based on the adenoma-carcinoma sequence in the Vogelstein model, serrated polyp pathway, and microsatellite instability. The genetic basis for hereditary nonpolyposis colorectal cancer is based on detection of genetic mutations. G
PMID 24267189

Wallace MB.SourceDivision of Gastroenterology and Hepatology, Mayo Clinic Florida, Jacksonville, Florida, USA.
Gastrointestinal endoscopy.Gastrointest Endosc.2013 Dec;78(6):910-1. doi: 10.1016/j.gie.2013.07.053.
PMID 24237946

Mixed serrated polyp（sessile serrated adenoma/polyp and traditional serrated adenoma）に併存して発生した盲腸SM癌の1例

下立雄一,高梨訓博,和賀永里子,藤田朋紀,勝木伸一,藤田昌宏
日本消化器内視鏡学会雑誌 55(10), 3409-3415, 2013
… 郭不明瞭が見られV<SUB>I</SUB>高度不整と診断した．SM深部浸潤癌と診断して外科的治療を薦めたが，本人の強い希望でESDを施行した．病理組織結果はWell and focal moderately differentiated adenocarcinoma with mixed serrated polyp，SM（1,900μm），ly1，v0，HM0，VM0であり，後日追加腸切除を行ったが腫瘍の残存は認めなかった．癌部および鋸歯状病変部のムチンコア蛋白発現，遺伝子解析の結果から本症例の発育進展過程を考察した …
NAID 130003386580

高山哲治,高岡遠,青木秀俊,岡本耕一
日本消化器内視鏡学会雑誌 55(6), 1787-1795, 2013
… 大腸癌の前病変としては，まず腺腫（adenoma）があげられ，腺腫はadenoma-carcinoma sequenceにより癌に進展する．次いで，traditional serrated adenoma（TSA）やsessile serrated adenoma/polyp（SSA/P）などの鋸歯状ポリープがあげられ，これらの病変はserrated pathwayにより癌に進展する．腺腫，TSA, SSA/Pの担癌率はいずれも約1 …
NAID 130003375308