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serine proteinase inhibitors

serine proteinase inhibitors

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/03/19 06:23:07」(JST)

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  • Polyphenols and their components in experimental allergic asthma.
  • Joskova M, Sadlonova V, Nosalova G, Novakova E, Franova S.SourceDepartment of Pharmacology, Comenius University, Martin, Slovakia.
  • Advances in experimental medicine and biology.Adv Exp Med Biol.2013;756:91-8. doi: 10.1007/978-94-007-4549-0_12.
  • The aim of the study was to investigate the potential anti-inflammatory effects in -experimental allergic asthma of natural polyphenolic compounds or their single major components. The experiment was performed after 21-days sensitization of guinea pigs with ovalbumin suspension. Changes in airway re
  • PMID 22836623
  • L-arginine supplementation and experimental airway hyperreactivity.
  • Antosova M, Strapkova A.SourceDepartment of Pharmacology, Comenius University, Martin, Slovakia.
  • Advances in experimental medicine and biology.Adv Exp Med Biol.2013;756:81-9. doi: 10.1007/978-94-007-4549-0_11.
  • The interest in L-arginine metabolism was triggered primarily by the discovery of nitric oxide (NO) synthesis in mammals and its remarkable biological roles. The real role of L-arginine in the airway hyperreactivity (AHR) has not been established yet. Therefore, we studied whether supplementation of
  • PMID 22836622
  • Effects of selective inhibition of PDE4 and PDE7 on airway reactivity and cough in healthy and ovalbumin-sensitized guinea pigs.
  • Mokry J, Joskova M, Mokra D, Christensen I, Nosalova G.SourceDepartment of Pharmacology, Comenius University, Martin, Slovakia.
  • Advances in experimental medicine and biology.Adv Exp Med Biol.2013;756:57-64. doi: 10.1007/978-94-007-4549-0_8.
  • Phosphodiesterases (PDEs) are enzymes responsible for degradation of cAMP and cGMP in cells. Thus, PDE inhibitors may have significant clinical benefit in respiratory diseases associated with inflammation. The aim of the present study was to evaluate the effects of selective PDE4 (rolipram, ROL) and
  • PMID 22836619


  • Structure and function of serpins involved in the regulation of blood coagulation and fibrinolysis
  • 林 辰弥,鈴木 宏治
  • 日本血栓止血学会誌 23(5), 481-493, 2012
  • NAID 130002077003
  • Molecular collaborations between serpins and trefoil factor promote endodermal cell growth and gastrointestinal differentiation in budding tunicates
  • Kawamura Kazuo,Kariya Yuko,Ono Yoshie [他],MURAMOTO Akira,OHTA Kyoko,FUJIWARA Shigeki
  • Development, growth & differentiation 48(5), 309-322, 2006-06-01
  • NAID 10019256791
  • A rat model of human FENIB (familial encephalopathy with neuroserpin inclusion bodies)
  • Takano Katsura,Kitao Yasuko,Inagi Reiko,Momoi Takashi,Matsuyama Tomohiro,Miyata Toshi,Yoneda Yukio,Iso Hiroyuki,Stern David M.,Hori Osamu,Ogawa Satoshi
  • Biochemical and Biophysical Research Communications 346(3), 1040-1047, 2006-04-00
  • … Tg meg rats provide a novel model of FENIB, where accumulation of serpins in the ER induces selective dysfunction/loss of specific neuronal populations. …
  • NAID 120000809734


Genes in the SERPIN gene superfamily provide instructions for making proteins called serine peptidase inhibitors or serpins. Most serpins help control certain chemical reactions by blocking (inhibiting) the function of ...
プロテアーゼからの保護 我々の細胞はこの破壊的機械を制御するため、機械の活動を阻害し危険を取り除く多くのタンパク質も作っている。セルピン(serpins)はこのような分子の中の一グループで、特定のセリンプロテアーゼ(serine ...



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