serotonm-dopamine antagonist

WordNet

a drug that neutralizes or counteracts the effects of another drug
a muscle that relaxes while another contracts; "when bending the elbow the triceps are the antagonist"
a monoamine neurotransmitter found in the brain and essential for the normal functioning of the central nervous system; as a drug (trade names Dopastat and Intropin) it is used to treat shock and hypotension (同)Dopastat, Intropin

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 制吐剤の特性 characteristics of antiemetic drugs
2. 胃不全麻痺の治療 treatment of gastroparesis
3. 悪性腫瘍関連胃不全麻痺：病態生理およびマネージメント malignancy associated gastroparesis pathophysiology and management
4. 成人における片頭痛の急性期治療 acute treatment of migraine in adults
5. 遅発性ジスキネジア：病因および疫学 tardive dyskinesia etiology and epidemiology

Smith LN1, Bachus SE2, McDonald CG2, Smith RF2.
Behavioural brain research.Behav Brain Res.2015 Aug 1;289:92-104. doi: 10.1016/j.bbr.2015.04.025. Epub 2015 Apr 20.
Adolescent cigarette use is associated with reduced quitting success and continued smoking in adulthood. Interestingly, polymorphisms of the dopamine D3 receptor (DRD3) gene have been associated with smoking behavior, and the receptor is expressed in an age- and brain region-dependent manner that su
PMID 25907750

Neuroprotection in Parkinsonian-treated mice via estrogen receptor α activation requires G protein-coupled estrogen receptor 1.

Bourque M1, Morissette M2, Di Paolo T3.
Neuropharmacology.Neuropharmacology.2015 Aug;95:343-52. doi: 10.1016/j.neuropharm.2015.04.006. Epub 2015 Apr 17.
We have previously shown that estrogen receptors (ER) α activation and G protein-coupled estrogen receptor 1 (GPER1) stimulation reproduce 17β-estradiol protection against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine induced toxicity of dopamine neurons in mice. This suggests that both ERα and GP
PMID 25892506

Serotonin6 receptors in the dorsal hippocampus regulate depressive-like behaviors in unilateral 6-hydroxydopamine-lesioned Parkinson's rats.

Liu KC1, Li JY1, Tan HH2, Du CX2, Xie W3, Zhang YM3, Ma WL1, Zhang L4.
Neuropharmacology.Neuropharmacology.2015 Aug;95:290-8. doi: 10.1016/j.neuropharm.2015.03.031. Epub 2015 Apr 9.
Preclinical studies indicate both activation and blockade of serotonin6 (5-HT6) receptors may produce antidepressant-like effects. Depression is a common symptom in Parkinson's disease (PD); however, its pathophysiology is unclear. Here we examined whether 5-HT6 receptors in the dorsal hippocampus (
PMID 25863121