serotonin receptor antagonist

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/05/18 16:16:53」(JST)

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英文文献

  • Role of spinal 5-HT5A, and 5-HT1A/1B/1D, receptors in neuropathic pain induced by spinal nerve ligation in rats.
  • Avila-Rojas SH1, Velázquez-Lagunas I1, Salinas-Abarca AB1, Barragán-Iglesias P1, Pineda-Farias JB1, Granados-Soto V2.
  • Brain research.Brain Res.2015 Oct 5;1622:377-85. doi: 10.1016/j.brainres.2015.06.043. Epub 2015 Jul 10.
  • Serotonin (5-HT) participates in pain modulation by interacting with different 5-HT receptors. The role of 5-HT5A receptor in neuropathic pain has not previously studied. The purpose of this study was to investigate: A) the role of 5-HT5A receptors in rats subjected to spinal nerve injury; B) the ex
  • PMID 26168890
  • Pharmacological profile of encounter-induced hyperactivity in isolation-reared mice.
  • Hasebe S1, Ago Y, Nishiyama S, Oka S, Hashimoto H, Takuma K, Matsuda T.
  • Behavioural pharmacology.Behav Pharmacol.2015 Oct;26(7 Spec No):681-90. doi: 10.1097/FBP.0000000000000140.
  • We have recently found that isolation-reared mice show hyperactivity during an encounter with an intruder. However, it is not known whether encounter-induced hyperactivity may model some aspects of psychiatric disorders. The present study examined the pharmacological profile of encounter-induced hyp
  • PMID 25932719
  • 5-HT3 receptors as important mediators of nausea and vomiting due to chemotherapy.
  • Navari RM1.
  • Biochimica et biophysica acta.Biochim Biophys Acta.2015 Oct;1848(10 Pt B):2738-2746. doi: 10.1016/j.bbamem.2015.03.020. Epub 2015 Mar 30.
  • Chemotherapy-induced nausea and vomiting (CINV) is associated with a significant deterioration in quality of life. The emetogenicity of the chemotherapeutic agents, repeated chemotherapy cycles, and patient risk factors significantly influence CINV. The use of a combination of a 5-hydroxytryptamine-
  • PMID 25838122

和文文献

  • Effect of the coadministration of citalopram with mirtazapine or atipamezole on rat contextual conditioned fear
  • Masuda Takahiro,Inoue Takeshi,An Yan,Takamura Naoki,Nakagawa Shin,Kitaichi Yuji,Koyama Tsukasa,Kusumi Ichiro
  • Neuropsychiatric disease and treatment 10, 289-295, 2014-02-11
  • … The addition of mirtazapine to selective serotonin reuptake inhibitors (SSRIs) is clinically suggested to be more effective for anxiety disorders. … Because mirtazapine blocks alpha(2)-adrenoreceptors, the combined effect of atipamezole, a selective alpha(2) receptor antagonist, with citalopram was also examined. …
  • NAID 120005411141
  • Industrial Info. 統合失調症治療薬
  • Endogenously released 5-HT inhibits A and C fiber-evoked synaptic transmission in the rat spinal cord by the facilitation of GABA/glycine and 5-HT release via 5-HT2A and 5-HT3 receptors
  • Iwasaki Takeyuki,Otsuguro Ken-ichi,Kobayashi Takeshi,Ohta Toshio,Ito Shigeo
  • European Journal of Pharmacology 702(1-3), 149-157, 2013-02-28
  • Serotonin (5-HT) released from descending fibers plays important roles in spinal functions such as locomotion and nociception. … The pCA-mediated inhibition was reversed by ketanserin (a 5-HT2A receptor antagonist) and tropisetron (a 5-HT3 receptor antagonist). …
  • NAID 120005228705

関連リンク

Serotonin receptors characteristics, classification and drugs that influence serotonergic transmission. Pharmacology review. ... Serotonin (5-hydroxytryptamine, 5-HT) is a key mediator in the physiology of mood, vascular function and ...
Introduction The serotonin type 3 (5-HT3) receptor antagonists are potent antiemetics used for prevention of postsurgical or chemotherapy induced nausea and vomiting and for some agents as therapy of diarrhea ...

関連画像

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★リンクテーブル★
関連記事antagonist」「receptor」「serotonin receptor」「serotonin

antagonist」

  [★] 拮抗薬

WordNet   license wordnet

「a drug that neutralizes or counteracts the effects of another drug」

WordNet   license wordnet

「a muscle that relaxes while another contracts; "when bending the elbow the triceps are the antagonist"」

PrepTutorEJDIC   license prepejdic

「対立する人,敵対者,競争相手(opponent)」


receptor」

  [★] 受容体

WordNet   license wordnet

「a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response」

PrepTutorEJDIC   license prepejdic

「=sense organ / 受信装置」


serotonin receptor」

  [★]

5-HT receptor5-HT1A receptor、5-HT1A serotonin receptor、5-HT1B receptor5-HT2A receptor5-HT2C receptor5-HT3 receptor


serotonin」

  [★] セロトニン 5-HT 5HT

WordNet   license wordnet

「a neurotransmitter involved in e.g. sleep and depression and memory」
5-hydroxytryptamine




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