WordNet

a substance that exerts some force or effect
a businessman who buys or sells for another in exchange for a commission (同)factor, broker
any agent or representative of a federal agency or bureau (同)federal agent
a representative who acts on behalf of other persons or organizations
an active and efficient cause; capable of producing a certain effect; "their research uncovered new disease agents"
how long something has existed; "it was replaced because of its age"
a time of life (usually defined in years) at which some particular qualification or power arises; "she was now of school age"; "tall for his eld" (同)eld
begin to seem older; get older; "The death of his wife caused him to age fast"
make older; "The death of his child aged him tremendously"

PrepTutorEJDIC

『代理人』;周旋人 / 働き(作用)を起こすもの;作用物,薬剤 / (政府機関,特にFBI,CIAなどの)部員,機関員
〈U〉(一般に)『年齢』,寿命;〈C〉(個々の)『年齢』,年 / 〈U〉成年(おとなとしての資格・権利を得る年齢;通例18または21歳) / 〈U〉『老齢』;《集合的に》老人たち / 〈U〉(人生の)『一時期』;〈C〉世代(generation) / 〈U〉〈C〉《しばしばA-》(歴史上の)『時代』 / 〈C〉《話》長い間 / 年をとる,ふける;〈物が〉古くなる / 〈年〉'を'とらせる;〈物〉'を'古びさせる

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/07/05 22:43:36」(JST)

wiki en

[Wiki en表示]

Serotonergic^{[pronunciation?]} or serotoninergic^{[pronunciation?]} means "working on the neurotransmitter serotonin". A synapse is serotonergic if it uses serotonin as its neurotransmitter. A serotonergic neuron produces serotonin. A substance is serotonergic if it produces its effects via interactions with the serotonin system.

A serotonergic, or serotonergic agent, is any chemical which functions to enhance the effects mediated by serotonin in the body. Some different types of serotonergics drugs include the following:

Serotonin receptor agonists and antagonists
Serotonin reuptake inhibitors
Serotonin releasing agents
Monoamine oxidase inhibitors

UpToDate Contents

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1. Serotonin syndrome (serotonin toxicity)
2. 悪性症候群 neuroleptic malignant syndrome
3. 成人における発熱の病態生理および治療 pathophysiology and treatment of fever in adults
4. 小児における、アデノイド切除同時施行例を含む扁桃摘出に対する麻酔 anesthesia for tonsillectomy with or without adenoidectomy in children
5. 最新の診療アップデート practice changing updates

English Journal

NMDA antagonists under investigation for the treatment of major depressive disorder.

Pochwat B1, Pałucha-Poniewiera A, Szewczyk B, Pilc A, Nowak G.
Expert opinion on investigational drugs.Expert Opin Investig Drugs.2014 May 12:1-12. [Epub ahead of print]
Introduction: Mood disorders, including depression, are becoming increasingly prevalent in the developed world. Furthermore, treatment of depression therapeutics, mainly influencing the serotonergic and adrenergic systems, is considered insufficient. The original NMDA-glutamate hypothesis mechanism
PMID 24818801

Asparagus racemosus attenuates anxiety-like behavior in experimental animal models.

Garabadu D1, Krishnamurthy S.
Cellular and molecular neurobiology.Cell Mol Neurobiol.2014 May;34(4):511-21. doi: 10.1007/s10571-014-0035-z. Epub 2014 Feb 21.
Asparagus racemosus Linn. (AR) is used worldwide as a medicinal plant. In the present study, the anxiolytic activity of standardized methanolic extract of root of AR (MAR) was evaluated in open-field test (OFT), hole-board, and elevated plus maze (EPM) tests. Rats received oral pretreatment of MAR i
PMID 24557501

Role of the 5-HT7 receptor in the effects of intrathecal nefopam in neuropathic pain in rats.

Dam LJ1, Hai L2, Ha YM3.
Neuroscience letters.Neurosci Lett.2014 Apr 30;566:50-4. doi: 10.1016/j.neulet.2014.02.021. Epub 2014 Feb 20.
Nefopam is a non-opioid analgesic drug, used widely in European countries to control postoperative pain. However, its mechanism of action remains unclear. In this study, the effects of intrathecal nefopam on spinal nerve-ligated induced neuropathic pain in rats were examined and the involvement of t
PMID 24561091

Japanese Journal

Social defeat stress induces hyperthermia through activation of thermoregulatory sympathetic premotor neurons in the medullary raphe region.

The European journal of neuroscience 34(9), 1442-1452, 2011-10-06
NAID 120005627632

Recreational drugs, 3,4-Methylenedioxymethamphetamine (MDMA), 3,4-methylenedioxyamphetamine (MDA) and diphenylprolinol, inhibit neurite outgrowth in PC12 cells

Journal of toxicological sciences 35(3), 375-381, 2010-06-01
NAID 10026469818

Decrease in the Kainate-Induced Wet Dog Shake Behavior in Genetically Epilepsy-Prone Rats : Possible Involvement of an Impaired Synaptic Transmission to the 5-HT_<2A> Receptor

Journal of pharmacological sciences 110(3), 401-404, 2009-07-20
NAID 10025738036

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★リンクテーブル★

リンク元	「5-HT agonist」「serotonin agonist」「serotonergic agonist」「セロトニン作用薬」「セロトニン性薬物」
関連記事	「agent」「age」「serotonergic」