WordNet
- detect some circumstance or entity automatically; "This robot can sense the presence of people in the room"; "particle detectors sense ionization"
- the faculty through which the external world is apprehended; "in the dark he had to depend on touch and on his senses of smell and hearing" (同)sensation, sentience, sentiency, sensory faculty
- the meaning of a word or expression; the way in which a word or expression or situation can be interpreted; "the dictionary gave several senses for the word"; "in the best sense charity is really a duty"; "the signifier is linked to the signified" (同)signified
- a general conscious awareness; "a sense of security"; "a sense of happiness"; "a sense of danger"; "a sense of self"
- a natural appreciation or ability; "a keen musical sense"; "a good sense of timing"
- comprehend; "I sensed the real meaning of his letter"
- detected by instinct or inference rather than by recognized perceptual cues; "the felt presence of an intruder"; "a sensed presence in the room raised goosebumps on her arms"; "a perceived threat" (同)perceived
- becoming aware of something via the senses (同)perception
- a fractional monetary unit of Japan and Indonesia and Cambodia; equal to one hundredth of a yen or rupiah or riel
PrepTutorEJDIC
- 〈C〉(五感による)『感覚』;(…の)感覚《+『of』+『名』》 / 〈U〉《しばしばa~》(…の)『感じ』,気持ち《+『of』+『名』》 / 〈U〉《a~,one's~》(…の)『理解』(『認識』)『力』,観念,センス《+『of』+『名』》 / 《one's senses》正常な感覚,正気 / 〈C〉《しばしば冠詩をつけないで》分別,良識 / 〈C〉(行動・発言・文などの)意義,意味(meaning)《+of(in)+名(do『ing』)》 / 〈U〉(…の)(全体的な)意向,動向《+『of』+『名』》 / …‘を'感ずる,‘に'気づく
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- 1. エボラウイルス病の治療および予防 treatment and prevention of ebola virus disease
- 2. 遺伝学およびゲノミクスのためのツール：細胞遺伝学および分子遺伝学 tools for genetics and genomics cytogenetics and molecular genetics
- 3. 原発性免疫不全症に対する遺伝子治療 gene therapy for primary immunodeficiency
- 4. クローン病の内科的マネージメントにおける試験研究治療 investigational therapies in the medical management of crohn disease
- 5. 遺伝学およびゲノミクスのためのツール：遺伝子発現プロファイリング tools for genetics and genomics gene expression profiling
English Journal
- Efficient generation of Knock-in/Knock-out marmoset embryo via CRISPR/Cas9 gene editing.
- Kumita W, Sato K, Suzuki Y, Kurotaki Y, Harada T, Zhou Y, Kishi N, Sato K, Aiba A, Sakakibara Y, Feng G, Okano H, Sasaki E.
- Scientific reports. 2019 Sep;9(1)12719.
- Genetically modified nonhuman primates (NHP) are useful models for biomedical research. Gene editing technologies have enabled production of target-gene knock-out (KO) NHP models. Target-gene-KO/knock-in (KI) efficiency of CRISPR/Cas9 has not been extensively investigated in marmosets. In this study
- PMID 31481684
- NFL is a marker of treatment response in children with SMA treated with nusinersen.
- Olsson B, Alberg L, Cullen NC, Michael E, Wahlgren L, Kroksmark AK, Rostasy K, Blennow K, Zetterberg H, Tulinius M.
- Journal of neurology. 2019 Sep;266(9)2129-2136.
- Recently, the anti-sense oligonucleotide drug nusinersen was approved for spinal muscular atrophy (SMA) and our aim was to find a response marker for this treatment. Twelve children with SMA type 1 and two copies of the SMN2 gene were included in a consecutive single-center study. The children were
- PMID 31123861
- Quantitative Fluorescence In Situ Hybridization (FISH) and Immunofluorescence (IF) of Specific Gene Products in KSHV-Infected Cells.
- Vallery TK, Steitz JA.
- Journal of visualized experiments : JoVE. 2019 Aug;(150).
- Mechanistic insight arrives from careful study and quantification of specific RNAs and proteins. The relative locations of these biomolecules throughout the cell at specific times can be captured with fluorescence in situ hybridization (FISH) and immunofluorescence (IF). During lytic herpesvirus inf
- PMID 31524859
Japanese Journal
- Design of Functional Nucleic Acid Systems for Biomolecular Analysis
- Sando Shinsuke
- Bulletin of the Chemical Society of Japan 84(2), 133-140, 2011
- … Fluorophore-labeled artificial oligonucleotide probes with target-dependent self-ligation or self-digestion functionalities can be used to sense nucleic acids in solution, on solid supports, or even in cells. …
- NAID 130004152868
- ヌクレアーゼ抵抗性化学修飾核酸の開発研究
- 松田 彰
- YAKUGAKU ZASSHI 131(2), 285-298, 2011
- … We found that siRNAs, which have 4 residues of SNs on both ends of the sense strand and 4 residues on the 3′-end of the antisense strand, were the most effective. … Since SMON duplexes were thermally more stable than unmodified ON duplexes, therefore they would be quite suitable to use for oligonucleotide therapeutics. …
- NAID 130000451463
- 我が国における動物バイオリソースの現状 ネッタイツメガエル--両生類の理想的な実験動物
- 柏木 啓子,柏木 昭彦,倉林 敦 [他],HANADA Hideki,NAKAJIMA Keisuke,OKADA Morihiro,TAKASE Minoru,YAOITA Yoshio
- Experimental Animals 59(4), 395-405, 2010
- … Since the 1950s Xenopus laevis in particular has been used by scientists in many fields for experiments, resulting in the development of various techniques such as microsurgery on early embryos, biosynthesis of gene-encoded protein in oocytes by mRNA injection, misexpression experiments by mRNA injection into embryos, gene knockdown studies by injection of morpholino anti-sense oligonucleotide into fertilized eggs, transgenesis by the I-SceI meganuclease method, and so on. …
- NAID 130000298600
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「antisense oligonucleotide」
「sense」
- n.
「sensing」
- n.
- adj.
- 感覚性の
- 関
- sensory