精細管内悪性胚細胞
WordNet
- small room in which a monk or nun lives (同)cubicle
- a device that delivers an electric current as the result of a chemical reaction (同)electric cell
- a room where a prisoner is kept (同)jail cell, prison cell
- (biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
- any small compartment; "the cells of a honeycomb"
- a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
- a small apparently simple structure (as a fertilized egg) from which new tissue can develop into a complete organism
- dangerous to health; characterized by progressive and uncontrolled growth (especially of a tumor)
- bearing or producing seed or semen; "seminiferous tubules"
PrepTutorEJDIC
- (刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞
- 細菌,ばい菌 / (植物の)胚(はい),幼芽;(動物の)卵子 / 原因;(発達の)初期
- 悪意のある,敵意のある / (病気が)悪性の
UpToDate Contents
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English Journal
- Evaluation of retained testes in adolescent girls and women with complete androgen insensitivity syndrome.
- Nakhal RS1, Hall-Craggs M, Freeman A, Kirkham A, Conway GS, Arora R, Woodhouse CR, Wood DN, Creighton SM.Author information 1Elizabeth Garrett Anderson UCL Institute of Women's Health, University College London Hospitals, 250 Euston Rd, London NW1 2PG, England. rola.nakhal@nhs.netAbstractPURPOSE: To evaluate the magnetic resonance (MR) imaging appearance of the testes in women with complete androgen insensitivity syndrome (CAIS), including any benign or malignant changes.
- Radiology.Radiology.2013 Jul;268(1):153-60. doi: 10.1148/radiol.13121068. Epub 2013 Mar 26.
- PURPOSE: To evaluate the magnetic resonance (MR) imaging appearance of the testes in women with complete androgen insensitivity syndrome (CAIS), including any benign or malignant changes.MATERIALS AND METHODS: This was a retrospective review of the testicular MR images and histologic reports from 25
- PMID 23533290
- CDX-2 expression in malignant germ cell tumors of the testes, intratubular germ cell neoplasia, and normal seminiferous tubules.
- Lee MJ1, Vogt AP, Hsiao W, Osunkoya AO.Author information 1Department of Pathology, Emory University School of Medicine, Room H174, 1364 Clifton Road, NE, Atlanta, GA 30322, USA.AbstractCDX-2 is a caudal-type homeobox gene, encoding a transcription factor that plays an important role in proliferation and differentiation of intestinal epithelial cells. The utility of antibodies to CDX2 in the identification of adenocarcinomas of the gastrointestinal tract, particularly colorectal adenocarcinomas, in both primary and metastatic settings is well established. It is well-known that patients with testicular tumors may occasionally lack an obvious palpable mass. However, the expression of CDX2 in malignant germ cell tumors of the testes which have metastatic potential has not been previously studied in a large series. A tissue microarray was constructed from 52 malignant germ cell tumors of the testes including: 29 cases of classic seminoma, 8 cases of embryonal carcinoma, 8 cases of yolk sac tumor, 4 cases of malignant teratoma, 2 cases of choriocarcinoma, and 1 case of spermatocytic seminoma. Ten cases of intratubular germ cell neoplasia and seven cases of benign testicles with normal seminiferous tubules were also included in tissue microarray. Immunohistochemical stains for CDX2 was performed and analyzed. Only nuclear staining was considered positive. Positive expression of CDX2 was identified in 2/2 cases (100 %) of choriocarcinoma, 4/8 cases (50 %) of teratoma, 3/8 cases (38 %) of embryonal carcinoma, 3/8 cases (38 %) of yolk sac tumor, and 1/29 cases (3 %) of classic seminoma. CDX2 was negative in all cases of intratubular germ cell neoplasia, normal seminiferous tubules, and the only case of spermatocytic seminoma. The role of CDX-2 in the differentiation of intestinal/enteric epithelial cells may contribute to the formation of trophoblastic, glandular, villous, or cystic structures in germ cell tumors of the testes. This study suggests that the expression of CDX2 in a variety of malignant germ cell tumors of the testes may be a potential pitfall in metastatic tumors of unknown primary, which are thought to be of gastrointestinal/colorectal origin but are actually from a clinically occult testicular tumor.
- Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.Tumour Biol.2012 Dec;33(6):2185-8. doi: 10.1007/s13277-012-0479-z. Epub 2012 Aug 16.
- CDX-2 is a caudal-type homeobox gene, encoding a transcription factor that plays an important role in proliferation and differentiation of intestinal epithelial cells. The utility of antibodies to CDX2 in the identification of adenocarcinomas of the gastrointestinal tract, particularly colorectal ad
- PMID 22895825
- Vanishing testes: a literature review.
- Pirgon Ö1, Dündar BN.Author information 1Süleyman Demirel University Faculty of Medicine, Department of Pediatric Endocrinology and Diabetes, Isparta, Turkey. ozgurpirgon@gmail.comAbstractVanishing testes syndrome is often referred to as testicular regression syndrome (TRS) in the recent medical literature. The most characteristic histological findings are presence of a fibrovascular nodule with associated hemosiderin-laden macrophages and dystrophic calcification. Residual testicular tubules are found in less than 10% of cases, with prevalence being unrelated to age at surgery. Presence of seminiferous tubules and viable germ cells in testicular remnant tissue has been reported in some series. TRS theoretically carries a potential for malignant degeneration in the long term and therefore removal of any remnant is a common practice to eliminate this risk. However, no case series has reported germinal dysplasia or intratubular germ cell neoplasia in any of the specimens taken from these patients.
- Journal of clinical research in pediatric endocrinology.J Clin Res Pediatr Endocrinol.2012 Sep;4(3):116-20. doi: 10.4274/Jcrpe.728.
- Vanishing testes syndrome is often referred to as testicular regression syndrome (TRS) in the recent medical literature. The most characteristic histological findings are presence of a fibrovascular nodule with associated hemosiderin-laden macrophages and dystrophic calcification. Residual testicula
- PMID 22985611
Related Links
- 精細管内悪性胚細胞の臨床 【精細管内悪性胚細胞とは】 精細管内悪性胚細胞seminiferous intratubular malignant germ cellとは、 時に男性不妊症患者の精細管から検出される、胚細胞腫瘍のごく初期の病像になります。 【精細管内悪性胚 ...
- RESEARCH ARTICLE CDX-2 expression in malignant germ cell tumors of the testes, intratubular germ cell neoplasia, and normal seminiferous tubules Michael J. Lee & Adam P. Vogt & Wayland Hsiao & Adeboye O. Osunkoya
★リンクテーブル★
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- 関
- 精細管内悪性胚細胞 seminiferous intratubular malignant germ cell
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- 英
- seminiferous intratubular malignant germ cell
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- 関
- anlage、anlagen、embryo、embryonic、germinal、microbe、microbial、microorganism、placode、primordia、primordium
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- 関
- gamete、germ line、germ-line cell
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- 関
- malignantly、pernicious
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細胞
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- 関
- intraductal