secretory IgA deficiency

分泌型IgA欠損症

WordNet

1. the 9th letter of the Roman alphabet (同)i
2. of or relating to or producing a secretion; " a secretory cell"

PrepTutorEJDIC

1. 〈U〉〈C〉(…の)(量・額などの)不足,欠乏《+『of』(『in』)+『名』》 / 〈C〉不足分,不足量,不足額 / 〈C〉(精神・肉体などの)欠陥
2. 『私は』私が
3. iodineの化学記号

UpToDate Contents

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• 1. 選択的IgA欠損症：臨床症状、病態生理、および診断 selective iga deficiency clinical manifestations pathophysiology and diagnosis
• 2. 選択的IgA欠損症：管理および予後 selective iga deficiency management and prognosis
• 3. 原発性の体液性免疫不全：概要 primary humoral immunodeficiencies an overview
• 4. Approach to the diagnosis of chronic diarrhea in children in resource-rich countries
• 5. IgGの構造および生物学的機能 structure and biologic functions of iga

English Journal

• Secretory IgA from submucosal glands does not compensate for its airway surface deficiency in chronic obstructive pulmonary disease.

• Du RH1, Richmond BW1, Blackwell TS Jr1, Cates JM2, Massion PP1,3,4, Ware LB1,2, Lee JW5, Kononov AV6, Lawson WE1,4, Blackwell TS1,7,3,4, Polosukhin VV8.
• Virchows Archiv : an international journal of pathology.Virchows Arch.2015 Dec;467(6):657-665. Epub 2015 Oct 2.
• Secretory immunoglobulin A (SIgA) reaches the airway lumen by local transcytosis across airway epithelial cells or with tracheobronchial submucosal gland secretions. In chronic obstructive pulmonary disease (COPD), deficiency of SIgA on the airway surface has been reported. However, reduction of SIg
• PMID 26432569

• Enhanced differentiation of intraepithelial lymphocytes in the intestine of polymeric immunoglobulin receptor-deficient mice.

• Kato-Nagaoka N1, Shimada S1, Yamakawa Y2, Tsujibe S1, Naito T1, Setoyama H1, Watanabe Y1, Shida K1, Matsumoto S1, Nanno M1.
• Immunology.Immunology.2015 Sep;146(1):59-69. doi: 10.1111/imm.12480. Epub 2015 Jun 26.
• To clarify the effect of secretory IgA (sIgA) deficiency on gut homeostasis, we examined intraepithelial lymphocytes (IELs) in the small intestine (SI) of polymeric immunoglobulin receptor-deficient (pIgR(-/-) ) mice. The pIgR(-/-) mice exhibited the accumulation of CD8αβ(+) T-cell receptor (TCR)-
• PMID 25967857

• IL-1β in eosinophil-mediated small intestinal homeostasis and IgA production.

• Jung Y1, Wen T2, Mingler MK2, Caldwell JM2, Wang YH2, Chaplin DD3, Lee EH4, Jang MH5, Woo SY6, Seoh JY6, Miyasaka M7, Rothenberg ME2.
• Mucosal immunology.Mucosal Immunol.2015 Jul;8(4):930-42. doi: 10.1038/mi.2014.123. Epub 2015 Jan 7.
• Eosinophils are multifunctional leukocytes that reside in the gastrointestinal (GI) lamina propria, where their basal function remains largely unexplored. In this study, by examining mice with a selective deficiency of systemic eosinophils (by lineage ablation) or GI eosinophils (eotaxin-1/2 double
• PMID 25563499

Japanese Journal

• ヒトIgAに対するイムノクロマトグラフィーの開発

• 京都女子大学食物学会誌 (70), 1-6, 2015-12
• NAID 120005825082

• MyD88 Deficiency Alters Expression of Antimicrobial Factors in Mouse Salivary Glands

• PLOS one 9(11), e113333, 2014-11-21
• NAID 120005540298

• 介護実習における唾液中分泌型IgAレベルおよび気分、不安感情の変動 : 実習に初めて参加する大学生を対象として

• 保健福祉学研究 2, 13-22, 2004-03-31
• NAID 110004708712

Related Links

• Selective IgA Deficiency | Immune Deficiency Foundation

Secretory IgA is made of two IgA antibody molecules joined together by a protein called the J chain (“J” for “joining”). (See chapter titled ...

• Selective IgA Deficiency | Primary Immunodeficiency (PI)

... which is why IgA is known as a secretory antibody. Because the area of a person's mucosal surfaces is equal to 1.5 tennis courts, the importance of IgA in protecting these surfaces cannot be overstated. Although people with ...

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★リンクテーブル★

リンク元	「分泌型IgA欠損症」
関連記事	「deficiency」「IgA」「I」「secretory」「Ig」

「分泌型IgA欠損症」

　　[★]

英

secretory IgA deficiency

「deficiency」

　　[★]

• n.

• 不足、欠乏、欠失、欠如、欠損、不十分。栄養不足、栄養素欠乏、欠乏症。(遺伝子)(染色体内の)遺伝子欠失
• 欠けているもの、不足している物。不足分。不完全なもの、欠点のあるもの

関

absence, agenesis, dearth, defect, defective, deficient, deficit, delete, deletion, deletional, depletion, deprivation, deprive, lack, miss, missing, morphological defect, paucity, scarce, scarcity, starve

　

「IgA」

　　[★]

英

immunoglobulin A

同

免疫グロブリンA γA gamma A

関

免疫グロブリン Ig

概念

• 免疫グロブリンクラスの1つ。

基準値

• 110-410 mg/dl (臨床検査法提要第32版)

臨床関連

• IgA欠損症

• 選択的IgA欠損症

• ヘノッホ・シェーンライン紫斑病
• IgA腎症
• 血清IgAの上昇：アルコール性肝障害　→　小腸のパイエル板におけるリンパ球の活動が亢進？？？

「I」

　　[★]

• イソロイシン isoleucine
• イノシン inosine
• 阻害剤 inhibitor
• iodine
• ヨード iodide
• I因子 factor I

　 　 　

「secretory」

　　[★]

• adj.

• 分泌性の、分泌型の

　

「Ig」

　　[★] 免疫グロブリン immunoglobulin