WordNet

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 肥大型心筋症：遺伝子変異および臨床遺伝子検査 hypertrophic cardiomyopathy gene mutations and clinical genetic testing
2. 肥大型心筋症：自然経過および予後 hypertrophic cardiomyopathy natural history and prognosis
3. 孤立性左室心筋緻密化障害 isolated left ventricular noncompaction
4. 拡張型心筋症の遺伝学 genetics of dilated cardiomyopathy
5. 高血圧における左室肥大の定義および病因 definition and pathogenesis of left ventricular hypertrophy in hypertension

A Cardiomyocyte-Specific Wdr1 Knockout Demonstrates Essential Functional Roles for Actin Disassembly during Myocardial Growth and Maintenance in Mice.

Yuan B1, Wan P1, Chu D2, Nie J1, Cao Y1, Luo W1, Lu S1, Chen J3, Yang Z4.
The American journal of pathology.Am J Pathol.2014 Jul;184(7):1967-80. doi: 10.1016/j.ajpath.2014.04.007. Epub 2014 May 16.
Actin dynamics are critical for muscle development and function, and mutations leading to deregulation of actin dynamics cause various forms of heritable muscle diseases. AIP1 is a major cofactor of the actin depolymerizing factor/cofilin in eukaryotes, promoting actin depolymerizing factor/cofilin-
PMID 24840128

Gne depletion during zebrafish development impairs skeletal muscle structure and function.

Daya A1, Vatine GD2, Becker-Cohen M3, Tal-Goldberg T3, Friedmann A4, Gothilf Y5, Du SJ6, Mitrani-Rosenbaum S7.
Human molecular genetics.Hum Mol Genet.2014 Jul 1;23(13):3349-61. doi: 10.1093/hmg/ddu045. Epub 2014 Jan 31.
GNE Myopathy is a rare recessively inherited neuromuscular disorder caused by mutations in the GNE gene, which codes for the key enzyme in the metabolic pathway of sialic acid synthesis. The process by which GNE mutations lead to myopathy is not well understood. By in situ hybridization and gne prom
PMID 24488768

Remodeling of the sarcomeric cytoskeleton in cardiac ventricular myocytes during heart failure and after cardiac resynchronization therapy.

Lichter JG1, Carruth E1, Mitchell C1, Barth AS2, Aiba T2, Kass DA3, Tomaselli GF2, Bridge JH4, Sachse FB5.
Journal of molecular and cellular cardiology.J Mol Cell Cardiol.2014 Jul;72:186-95. doi: 10.1016/j.yjmcc.2014.03.012. Epub 2014 Mar 20.
Sarcomeres are the basic contractile units of cardiac myocytes. Recent studies demonstrated remodeling of sarcomeric proteins in several diseases, including genetic defects and heart failure. Here we investigated remodeling of sarcomeric α-actinin in two models of heart failure, synchronous (SHF) a
PMID 24657727

Apoptosis-Resistant Cardiac Progenitor Cells Modified With Apurinic/Apyrimidinic Endonuclease/Redox Factor 1 Gene Overexpression Regulate Cardiac Repair After Myocardial Infarction.

The myocardial regenerative potential of three-dimensional engineered cardiac tissues composed of multiple human iPS cell-derived cardiovascular cell lineages